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Sudha K. Shenoy

Sudha K. Shenoy

D-Index & Metrics

Biology and Biochemistry

D-Index
46
Citations
18238
World Ranking
18816
National Ranking
7685

Overview

Sudha K. Shenoy is affiliated with Duke University in the United States and conducts research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work encompasses molecular biology, physiology, oncology, cell biology, and surgery, with a predominant focus on molecular biology.

The main research topics addressed in their publications include:

  • Receptor Mechanisms and Signaling
  • Ubiquitin and proteasome pathways
  • Peptidase Inhibition and Analysis
  • Cellular transport and secretion
  • Pancreatic function and diabetes
  • Eicosanoids and Hypertension Pharmacology
  • Adenosine and Purinergic Signaling

Shenoy has contributed multiple articles to various scientific journals, with the most frequent publication venues being:

  • Journal of Biological Chemistry (5 publications)
  • Cell (1 publication)
  • Current Opinion in Physiology (1 publication)
  • Nature Communications (1 publication)
  • American Journal of Physiology-Heart and Circulatory Physiology (1 publication)

Recent notable papers include:

  • "SnapShot: β-Arrestin Functions," 2020, published in Cell
  • "Agonist-activated glucagon receptors are deubiquitinated at early endosomes by two distinct deubiquitinases to facilitate Rab4a-dependent recycling," 2020, published in Journal of Biological Chemistry
  • "An insulin-regulated arrestin domain protein controls hepatic glucagon action," 2023, published in Journal of Biological Chemistry
  • "Phosphorylation of USP20 on Ser334 by IRAK1 promotes IL-1β-evoked signaling in vascular smooth muscle cells and vascular inflammation," 2023, published in Journal of Biological Chemistry
  • "How carvedilol does not activate β2-adrenoceptors," 2023, published in Nature Communications

The scientist frequently collaborates with colleagues such as Suneet Kaur, Bipradas Roy, Jiao-Hui Wu, Pierre-Yves Jean-Charles, and Neil J. Freedman, with these collaborators appearing multiple times across Shenoy's body of work.

Best Publications

  • Transduction of receptor signals by beta-arrestins.

    Robert J. Lefkowitz;Sudha K. Shenoy;Sudha K. Shenoy

  • β-Arrestins and Cell Signaling

    Scott M. DeWire;Seungkirl Ahn;Robert J. Lefkowitz;Sudha K. Shenoy

  • Regulation of Receptor Fate by Ubiquitination of Activated β2-Adrenergic Receptor and β-Arrestin

    Sudha K. Shenoy;Patricia H. McDonald;Trudy A. Kohout;Robert J. Lefkowitz

  • β-arrestin-mediated receptor trafficking and signal transduction

    Sudha K. Shenoy;Robert J. Lefkowitz;Robert J. Lefkowitz

  • β-Arrestin-dependent, G Protein-independent ERK1/2 Activation by the β2 Adrenergic Receptor

    Sudha K. Shenoy;Matthew T. Drake;Christopher D. Nelson;Daniel A. Houtz

  • A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling

    James W. Wisler;Scott M. DeWire;Erin J. Whalen;Jonathan D. Violin

  • Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2

    Huijun Wei;Seungkirl Ahn;Sudha K. Shenoy;Sadashiva S. Karnik

  • Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor

    Seungkirl Ahn;Sudha K. Shenoy;Huijun Wei;Robert J. Lefkowitz;Robert J. Lefkowitz

  • Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin.

    Kelly N. Nobles;Kunhong Xiao;Seungkirl Ahn;Arun K. Shukla;Arun K. Shukla

  • Multifaceted roles of β-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling

    Sudha K. Shenoy;Robert J. Lefkowitz

  • Functional specialization of β-arrestin interactions revealed by proteomic analysis

    Kunhong Xiao;Daniel B. McClatchy;Arun K. Shukla;Yang Zhao

  • A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1.

    Makoto R. Hara;Jeffrey J. Kovacs;Erin J. Whalen;Sudarshan Rajagopal

  • Trafficking of G Protein–Coupled Receptors

    Matthew T. Drake;Sudha K. Shenoy;Robert J. Lefkowitz

  • Trafficking Patterns of β-Arrestin and G Protein-coupled Receptors Determined by the Kinetics of β-Arrestin Deubiquitination

    Sudha K. Shenoy;Robert J. Lefkowitz;Robert J. Lefkowitz

  • β-Arrestin-biased Agonism at the β2-Adrenergic Receptor

    Matthew T. Drake;Jonathan D. Violin;Erin J. Whalen;James W. Wisler

  • GPCR desensitization: Acute and prolonged phases

    Sudarshan Rajagopal;Sudha K. Shenoy;Sudha K. Shenoy

  • Distinct conformational changes in β-arrestin report biased agonism at seven-transmembrane receptors

    Arun K. Shukla;Jonathan D. Violin;Erin J. Whalen;Diane Gesty-Palmer

  • Introduction to Special Section on β-Arrestins

    Robert Lefkowitz

  • A unique mechanism of -blocker action: Carvedilol stimulates -arrestin signaling

    James W. Wisler;Scott M. DeWire;Erin J. Whalen;Jonathan D. Violin

  • Compartmentation of Cyclic Nucleotide Signaling in the Heart: The Role of Cyclic Nucleotide Phosphodiesterases

    Matthew T. Drake;Sudha K. Shenoy;Robert J. Lefkowitz

Frequent Co-Authors

Robert J. Lefkowitz
Robert J. Lefkowitz Duke University
Seungkirl Ahn
Seungkirl Ahn Duke University
Linda Yu
Linda Yu Oklahoma State University
Louis M. Luttrell
Louis M. Luttrell Medical University of South Carolina
Howard A. Rockman
Howard A. Rockman Duke University
Eric Reiter
Eric Reiter François Rabelais University
Larry S. Barak
Larry S. Barak Duke University
Elizabeth R. Hauser
Elizabeth R. Hauser Duke University
Richard T. Premont
Richard T. Premont University Hospitals of Cleveland
Johann Deisenhofer
Johann Deisenhofer The University of Texas Southwestern Medical Center

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