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D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
32795
World Ranking
3260
National Ranking
1650

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Louis M. Luttrell is affiliated with the Medical University of South Carolina in the United States. Their research spans primary fields such as Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on subfields including Molecular Biology, Oncology, Biochemistry, Computational Theory and Mathematics, and Cellular and Molecular Neuroscience.

The main topics covered in their work include Receptor Mechanisms and Signaling, Eicosanoids and Hypertension Pharmacology, Computational Drug Discovery Methods, Neuropeptides and Animal Physiology, Coagulation, Bradykinin, Polyphosphates, and Angioedema, as well as Apelin-related biomedical research and GDF15 and Related Biomarkers.

Notable recent publications include:

  • SnapShot: β-Arrestin Functions, 2020, Cell
  • β-Arrestin2 is a critical component of the GPCR-eNOS signalosome, 2020, Proceedings of the National Academy of Sciences
  • Aging-related modifications to G protein-coupled receptor signaling diversity, 2020, Pharmacology & Therapeutics
  • Longitudinal Plasma Kallikrein Levels and Their Association With the Risk of Cardiovascular Disease Outcomes in Type 1 Diabetes in DCCT/EDIC, 2020, Diabetes
  • DPP4-Truncated CXCL12 Alters CXCR4/ACKR3 Signaling, Osteogenic Cell Differentiation, Migration, and Senescence, 2022, ACS Pharmacology & Translational Science

Frequent co-authors in Luttrell's research include Songling Liu, Richard T. Premont, Don C. Rockey, Seungkirl Ahn, and Sudha K. Shenoy.

Their work has been published multiple times in key venues such as Proceedings of the National Academy of Sciences, Cell, Pharmacology & Therapeutics, Diabetes, and ACS Pharmacology & Translational Science.

Louis M. Luttrell is recognized as a Member of the Association of American Physicians.

Best Publications

  • Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes.

    L. M. Luttrell;S. S. G. Ferguson;Y. Daaka;W. E. Miller

  • Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A.

    Yehia Daaka;Louis M. Luttrell;Robert J. Lefkowitz

  • The role of β-arrestins in the termination and transduction of G-protein-coupled receptor signals

    Louis M. Luttrell;Robert J. Lefkowitz;Robert J. Lefkowitz

  • Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds.

    Louis M. Luttrell;Francine L. Roudabush;Eric W. Choy;William E. Miller

  • Regulation of tyrosine kinase cascades by G-protein-coupled receptors.

    Louis M Luttrell;Yehia Daaka;Robert J Lefkowitz

  • Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway

    T van Biesen;B E Hawes;D K Luttrell;K M Krueger

  • Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2

    Huijun Wei;Seungkirl Ahn;Sudha K. Shenoy;Sadashiva S. Karnik

  • Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases

    Louis M. Luttrell;Brian E. Hawes;Tim van Biesen;Deirdre K. Luttrell

  • Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase

    Yehia Daaka;Louis M. Luttrell;Seungkirl Ahn;Gregory J. Della Rocca

  • Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor A SCAFFOLD FOR G PROTEIN-COUPLED RECEPTOR-MEDIATED Ras ACTIVATION

    Louis M. Luttrell;Gregory J. Della Rocca;Tim van Biesen;Deirdre K. Luttrell

  • Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors CONVERGENCE OF Gi- AND Gq-MEDIATED PATHWAYS ON CALCIUM/CALMODULIN, Pyk2, AND Src KINASE

    Gregory J. Della Rocca;Tim van Biesen;Yehia Daaka;Deirdre K. Luttrell

  • Mitogenic Signaling via G Protein-Coupled Receptors

    T van Biesen;LM Luttrell;BE Hawes;RJ Lefkowitz

  • Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy.

    Shahab A. Akhter;Louis M. Luttrell;Howard A. Rockman;Guido Iaccarino

  • New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades.

    Kristen L Pierce;Kristen L Pierce;Louis M Luttrell;Robert J Lefkowitz;Robert J Lefkowitz

  • Phosphatidylinositol 3-Kinase Is an Early Intermediate in the Gβγ-mediated Mitogen-activated Protein Kinase Signaling Pathway

    Brian E. Hawes;Louis M. Luttrell;Tim van Biesen;Robert J. Lefkowitz

  • Distinct pathways of Gi- and Gq-mediated mitogen-activated protein kinase activation

    Brian E. Hawes;Tim van Biesen;Walter J. Koch;Louis M. Luttrell

  • β-Arrestin Scaffolding of the ERK Cascade Enhances Cytosolic ERK Activity but Inhibits ERK-mediated Transcription following Angiotensin AT1a Receptor Stimulation

    Akira Tohgo;Kristen L. Pierce;Eric W. Choy;Robert J. Lefkowitz

  • Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling.

    W.J. Koch;B.E. Hawes;J. Inglese;L.M. Luttrell

  • The β2-Adrenergic Receptor Mediates Extracellular Signal-regulated Kinase Activation via Assembly of a Multi-receptor Complex with the Epidermal Growth Factor Receptor

    Stuart Maudsley;Kristen L. Pierce;A.Musa Zamah;William E. Miller

  • Distinct β-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation

    Diane Gesty-Palmer;Minyong Chen;Eric Reiter;Seungkirl Ahn

Frequent Co-Authors

Robert J. Lefkowitz
Robert J. Lefkowitz Duke University
Maria F. Lopes-Virella
Maria F. Lopes-Virella Medical University of South Carolina
Seungkirl Ahn
Seungkirl Ahn Duke University
John R. Raymond
John R. Raymond Medical College of Wisconsin
Yehia Daaka
Yehia Daaka University of Florida
Walter J. Koch
Walter J. Koch Temple University
Howard A. Rockman
Howard A. Rockman Duke University
Stephen S. G. Ferguson
Stephen S. G. Ferguson University of Ottawa
John M. Lachin
John M. Lachin George Washington University
Lina M. Obeid
Lina M. Obeid Stony Brook University

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