Yehia Daaka spends much of his time researching Cell biology, G protein-coupled receptor, G protein-coupled receptor kinase, Receptor tyrosine kinase and Biochemistry. His study in Tyrosine phosphorylation, Mitogen-activated protein kinase kinase, Phosphorylation, Heterotrimeric G protein and SH3 domain are all subfields of Cell biology. His G protein-coupled receptor study is concerned with Receptor in general.
His Receptor research focuses on Signal transduction and how it relates to Agonist. His study looks at the intersection of G protein-coupled receptor kinase and topics like Beta adrenergic receptor kinase with Protein kinase A. His Receptor tyrosine kinase research integrates issues from Proto-oncogene tyrosine-protein kinase Src, MAPK/ERK pathway and Dynamin.
Yehia Daaka mainly investigates Cell biology, Cancer research, Receptor, Signal transduction and Prostate cancer. His study in Cell biology is interdisciplinary in nature, drawing from both Biochemistry and Endocytosis. His Cancer research study combines topics from a wide range of disciplines, such as Cancer, Prostate, Metastasis, Tyrosine kinase and MAPK/ERK pathway.
His Receptor research incorporates elements of Stimulation and Pharmacology. His Prostate cancer research incorporates themes from Tumor progression, Endocrinology and G protein. His Receptor tyrosine kinase study incorporates themes from Proto-oncogene tyrosine-protein kinase Src and Tyrosine phosphorylation.
His scientific interests lie mostly in Cancer research, Prostate cancer, Androgen receptor, Cell biology and Metastasis. Yehia Daaka interconnects Prostate, Cancer cell, Intravasation, Receptor and Signal transduction in the investigation of issues within Cancer research. His research in Receptor intersects with topics in Progressive disease, Carcinoma and MAPK/ERK pathway.
In general Androgen receptor, his work in Castration Resistance is often linked to Transcriptional regulation and Transactivation linking many areas of study. His research on Cell biology frequently links to adjacent areas such as Cofilin. Yehia Daaka has included themes like Cell and Heterotrimeric G protein in his Metastasis study.
Yehia Daaka mainly focuses on Cell biology, Prostate cancer, G protein-coupled receptor kinase, Cancer research and Internal medicine. His research in Cell biology intersects with topics in Cofilin and Small interfering RNA. His research integrates issues of Metastasis and Kinase, Kinase activity in his study of Prostate cancer.
His studies deal with areas such as Arrestin, Cell, Cell signaling and Heterotrimeric G protein as well as G protein-coupled receptor kinase. His Cancer research study combines topics in areas such as Cell growth, Fatty acid synthase, Signal transducing adaptor protein and Gene knockdown. His research in the fields of Androgen receptor, Mediator and Internalization overlaps with other disciplines such as Amyloid precursor protein secretase.
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Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes.
L. M. Luttrell;S. S. G. Ferguson;Y. Daaka;W. E. Miller.
Science (1999)
Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A.
Yehia Daaka;Louis M. Luttrell;Robert J. Lefkowitz.
Nature (1997)
Regulation of tyrosine kinase cascades by G-protein-coupled receptors.
Louis M Luttrell;Yehia Daaka;Robert J Lefkowitz.
Current Opinion in Cell Biology (1999)
Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors CONVERGENCE OF Gi- AND Gq-MEDIATED PATHWAYS ON CALCIUM/CALMODULIN, Pyk2, AND Src KINASE
Gregory J. Della Rocca;Tim van Biesen;Yehia Daaka;Deirdre K. Luttrell.
Journal of Biological Chemistry (1997)
Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase
Yehia Daaka;Louis M. Luttrell;Seungkirl Ahn;Gregory J. Della Rocca.
Journal of Biological Chemistry (1998)
Molecular Basis for Interactions of G Protein βγ Subunits with Effectors
Carolyn E. Ford;Nikolai P. Skiba;Hyunsu Bae;Yehia Daaka.
Science (1998)
The β2-Adrenergic Receptor Mediates Extracellular Signal-regulated Kinase Activation via Assembly of a Multi-receptor Complex with the Epidermal Growth Factor Receptor
Stuart Maudsley;Kristen L. Pierce;A.Musa Zamah;William E. Miller.
Journal of Biological Chemistry (2000)
The Role of Sequestration in G Protein-coupled Receptor Resensitization REGULATION OF β2-ADRENERGIC RECEPTOR DEPHOSPHORYLATION BY VESICULAR ACIDIFICATION
Kathleen M. Krueger;Yehia Daaka;Julie A. Pitcher;Robert J. Lefkowitz.
Journal of Biological Chemistry (1997)
G Protein-coupled Receptors Mediate Two Functionally Distinct Pathways of Tyrosine Phosphorylation in Rat 1a Fibroblasts Shc PHOSPHORYLATION AND RECEPTOR ENDOCYTOSIS CORRELATE WITH ACTIVATION OF Erk KINASES
Louis M. Luttrell;Yehia Daaka;Gregory J. Della Rocca;Robert J. Lefkowitz.
Journal of Biological Chemistry (1997)
Src-mediated Tyrosine Phosphorylation of Dynamin Is Required for β2-Adrenergic Receptor Internalization and Mitogen-activated Protein Kinase Signaling
Seungkirl Ahn;Stuart Maudsley;Louis M. Luttrell;Robert J. Lefkowitz.
Journal of Biological Chemistry (1999)
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