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Immunology

D-Index
41
Citations
5875
World Ranking
4918
National Ranking
217

Overview

Mirella Profita is affiliated with the National Research Council (CNR) in Italy. Their research primarily focuses on the intersection of medicine, biochemistry, genetics, and molecular biology, with a strong emphasis on pulmonary and respiratory medicine.

Profita's work spans several main fields of study including:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields within their research include:

  • Pulmonary and Respiratory Medicine
  • Molecular Biology
  • Health, Toxicology and Mutagenesis
  • Cancer Research
  • Surgery

The scientist's main topics of investigation cover a diverse range of areas related to both respiratory health and cellular processes:

  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Hydrogen's biological and therapeutic effects
  • Asthma and respiratory diseases
  • Air Quality and Health Impacts
  • Autophagy in Disease and Therapy
  • Allergic Rhinitis and Sensitization
  • Cancer-related molecular mechanisms research

Profita has contributed numerous papers to scientific literature, with recent publications including:

  • "Overview of the Mechanisms of Oxidative Stress: Impact in Inflammation of the Airway Diseases" (2022), published in Antioxidants
  • "Impact of Air Pollution in Airway Diseases: Role of the Epithelial Cells (Cell Models and Biomarkers)" (2022), published in International Journal of Molecular Sciences
  • "Autophagy/Mitophagy in Airway Diseases: Impact of Oxidative Stress on Epithelial Cells" (2023), published in Biomolecules
  • "PBDEs affect inflammatory and oncosuppressive mechanisms via the EZH2 methyltransferase in airway epithelial cells" (2021), published in Life Sciences
  • "Endotyping Seasonal Allergic Rhinitis in Children: A Cluster Analysis" (2022), published in Frontiers in Medicine

The scientist has published frequently in the following journals:

  • International Journal of Molecular Sciences
  • Life Sciences
  • Immunobiology
  • Antioxidants
  • Biomolecules

Frequent collaborators include:

  • Angela Marina Montalbano
  • Giusy Daniela Albano
  • Rosalia Gagliardo
  • Giulia Anzalone
  • Caterina Di Sano

Best Publications

  • Sputum Metalloproteinase-9/Tissue Inhibitor of Metalloproteinase-1 Ratio Correlates with Airflow Obstruction in Asthma and Chronic Bronchitis

    Antonio M. Vignola;Loredana Riccobono;Angela Mirabella;Mirella Profita

  • Evaluation of apoptosis of eosinophils, macrophages, and T lymphocytes in mucosal biopsy specimens of patients with asthma and chronic bronchitis.

    Antonio M. Vignola;Pascal Chanez;Giuseppina Chiappara;Liboria Siena

  • Muscarinic receptors, leukotriene B4 production and neutrophilic inflammation in COPD patients

    M. Profita;R. Di Giorgi;A. Sala;A. Bonanno

  • Increased Levels of Elastase and α1-Antitrypsin in Sputum of Asthmatic Patients

    Antonio M. Vignola;Anna Bonanno;Angela Mirabella;Loredana Riccobono

  • Circulating hematopoietic progenitor cells in runners.

    Maria R. Bonsignore;Giuseppe Morici;Alessandra Santoro;Maria Pagano

  • Leptin and leptin receptor expression in asthma

    Andreina Bruno;Elisabetta Pace;Pascal Chanez;Delphine Gras

  • Airway inflammation in nonasthmatic amateur runners

    Maria R. Bonsignore;Giuseppe Morici;Loredana Riccobono;Giuseppe Insalaco

  • Identification of IL-17F/frequent exacerbator endotype in asthma

    Fabio Luigi Massimo Ricciardolo;Valentina Sorbello;Anna Folino;Fabio Gallo

  • Acetylcholine mediates the release of IL-8 in human bronchial epithelial cells by a NFkB/ERK-dependent mechanism

    Mirella Profita;Anna Bonanno;Liboria Siena;Maria Ferraro;Maria Ferraro

  • Increased prostaglandin E2 concentrations and cyclooxygenase-2 expression in asthmatic subjects with sputum eosinophilia.

    Mirella Profita;Angelo Sala;Anna Bonanno;Loredana Riccobono

  • Chronic obstructive pulmonary disease and neutrophil infiltration: role of cigarette smoke and cyclooxygenase products.

    Mirella Profita;Angelo Sala;Anna Bonanno;Loredana Riccobono

  • Increased airway inflammatory cells in endurance athletes: what do they mean?

    Maria R. Bonsignore;G. Morici;A. M. Vignola;L. Riccobono

  • Interleukin-8 induces lymphocyte chemotaxis into the pleural space. Role of pleural macrophages.

    Elisabetta Pace;Mark Gjomarkaj;Mario Melis;Mirella Profita

  • IL-33/ST2 axis controls Th2/IL-31 and Th17 immune response in allergic airway diseases.

    Lavinia Vocca;Caterina Di Sano;Carina G. Uasuf;Angelo Sala

  • Bronchial epithelial damage after a half-marathon in nonasthmatic amateur runners

    Laura Chimenti;Giuseppe Morici;Giuseppe Morici;Alessandra Paternò;Roberta Santagata

  • Smoke, Choline Acetyltransferase, Muscarinic Receptors, and Fibroblast Proliferation in Chronic Obstructive Pulmonary Disease

    Mirella Profita;Anna Bonanno;Liboria Siena;Andreina Bruno

  • Airway cells after swimming outdoors or in the sea in nonasthmatic athletes.

    Maria R. Bonsignore;Giuseppe Morici;Loredana Riccobono;Mirella Profita

  • Noninvasive methods for the detection of upper and lower airway inflammation in atopic children.

    Mirella Profita;Stefania La Grutta;Elisiana Carpagnano;Loredana Riccobono

  • 15(S)-HETE modulates LTB4 production and neutrophil chemotaxis in chronic bronchitis

    Mirella Profita;Angelo Sala;Loredana Riccobono;Elisabetta Pace

  • Biochemical interaction between effects of beclomethasone dipropionate and salbutamol or formoterol in sputum cells from mild to moderate asthmatics

    M. Profita;R. Gagliardo;R. Di Giorgi;F. Pompeo

  • Cytotoxic and genotoxic effects of the flame retardants (PBDE-47, PBDE-99 and PBDE-209) in human bronchial epithelial cells.

    Angela Marina Montalbano;Giusy Daniela Albano;Giulia Anzalone;Monica Moscato

Frequent Co-Authors

Pascal Chanez
Pascal Chanez Aix-Marseille University
Jean Bousquet
Jean Bousquet University of Montpellier
Giovanni Rolla
Giovanni Rolla University of Turin
Giorgio Ciprandi
Giorgio Ciprandi University of Genoa
Sally E. Wenzel
Sally E. Wenzel University of Pittsburgh
Peter M. Henson
Peter M. Henson National Jewish Health
Ugo Testa
Ugo Testa Istituto Superiore di Sanità
Robert C. Murphy
Robert C. Murphy University of Colorado Denver
Gert Folkerts
Gert Folkerts Utrecht University
Galen B. Toews
Galen B. Toews University of Michigan–Ann Arbor

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