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Immunology

D-Index
63
Citations
14487
World Ranking
3024
National Ranking
1417

Overview

Thomas W. Klein is affiliated with the University of South Florida in the United States. Their research primarily focuses on the field of medicine, with a specific emphasis on endocrinology, diabetes, and metabolism. Additional subfields include surgery, molecular biology, oncology, and infectious diseases.

The scientist's work encompasses several main topics, including:

  • Diabetes Treatment and Management
  • Pancreatic function and diabetes
  • Peptidase Inhibition and Analysis
  • Neuropeptides and Animal Physiology
  • COVID-19 Clinical Research Studies
  • Pancreatitis Pathology and Treatment
  • Regulation of Appetite and Obesity

Thomas W. Klein has contributed publications to various scientific venues. Frequent publication outlets for their work include:

  • Diabetes
  • Biomedicine & Pharmacotherapy
  • International Journal of Molecular Sciences
  • Scientific Reports
  • ChemMedChem

Recent papers authored by Thomas W. Klein cover a range of topics related to inflammation, diabetes, kidney function, and genetics. Selected publications include:

  • Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and Fibrosis, 2022, Cellular and Molecular Gastroenterology and Hepatology
  • SGLT2 Inhibitor Empagliflozin and DPP4 Inhibitor Linagliptin Reactivate Glomerular Autophagy in db/db Mice, a Model of Type 2 Diabetes, 2020, International Journal of Molecular Sciences
  • Renoprotective effects of empagliflozin are linked to activation of the tubuloglomerular feedback mechanism and blunting of the complement system, 2023, American Journal of Physiology-Cell Physiology
  • Empagliflozin reduces kidney fibrosis and improves kidney function by alternative macrophage activation in rats with 5/6-nephrectomy, 2022, Biomedicine & Pharmacotherapy
  • Mutations and variants of ONECUT1 in diabetes, 2021, Nature Medicine

The scientist has collaborated frequently with other researchers. Regular co-authors include:

  • Denis Delić
  • Berthold Hocher
  • Bernhard K. Krämer
  • Ahmed A. Hasan
  • Mohamed M. S. Gaballa

Best Publications

  • Cannabinoid-based drugs as anti-inflammatory therapeutics

    Thomas W. Klein

  • The cannabinoid system and immune modulation

    Thomas W. Klein;Cathy Newton;Kellie Larsen;Lily Lu

  • Randomized controlled trial of mindfulness-based stress reduction (MBSR) for survivors of breast cancer

    Cecile A. Lengacher;Versie Johnson-Mallard;Janice Post-White;Manolete S. Moscoso

  • Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation.

    Jared Ehrhart;Demian Obregon;Takashi Mori;Takashi Mori;Huayan Hou

  • Microbial Infections, Immunomodulation, and Drugs of Abuse

    Herman Friedman;Catherine Newton;Thomas W. Klein

  • Cannabinoid receptors and immunity

    Thomas W Klein;Cathy Newton;Herman Friedman

  • Involvement of Nicotinic Acetylcholine Receptors in Suppression of Antimicrobial Activity and Cytokine Responses of Alveolar Macrophages to Legionella pneumophila Infection by Nicotine

    Kazuto Matsunaga;Thomas W. Klein;Herman Friedman;Yoshimasa Yamamoto

  • The Cannabinoid System and Cytokine Network

    Thomas W. Klein;Brian Lane;Catherine A. Newton;Herman Friedman

  • Growth of Legionella pneumophila in thioglycolate-elicited peritoneal macrophages from A/J mice.

    Y Yamamoto;T W Klein;C A Newton;R Widen

  • Addictive drugs and their relationship with infectious diseases.

    Herman Friedman;Susan Pross;Thomas W. Klein

  • Marijuana, immunity and infection

    Thomas W Klein;Herman Friedman;Steven Specter

  • Bacterial heat shock proteins directly induce cytokine mRNA and interleukin-1 secretion in macrophage cultures.

    C Retzlaff;Y Yamamoto;P S Hoffman;H Friedman

  • Involvement of mannose receptor in cytokine interleukin-1beta (IL-1beta), IL-6, and granulocyte-macrophage colony-stimulating factor responses, but not in chemokine macrophage inflammatory protein 1beta (MIP-1beta), MIP-2, and KC responses, caused by attachment of Candida albicans to macrophages.

    Y Yamamoto;T W Klein;H Friedman

  • Spatial Learning Impairment in Mice Infected with Legionella pneumophila or Administered Exogenous Interleukin-1-β

    Unknown

  • Cannabinoid-Induced Immune Suppression and Modulation of Antigen-Presenting Cells

    Thomas W. Klein;Guy A. Cabral

  • Delta 9-tetrahydrocannabinol treatment suppresses immunity and early IFN-gamma, IL-12, and IL-12 receptor beta 2 responses to Legionella pneumophila infection.

    Thomas W. Klein;Catherine A. Newton;Noryia Nakachi;Herman Friedman

  • Secondary immunity to Legionella pneumophila and Th1 activity are suppressed by delta-9-tetrahydrocannabinol injection.

    C A Newton;T W Klein;H Friedman

  • Protective effects of tumor necrosis factor in experimental Legionella pneumophila infections of mice via activation of PMN function

    D K Blanchard;J Y Djeu;T W Klein;H Friedman

  • Delta9-tetrahydrocannabinol induces apoptosis in macrophages and lymphocytes: involvement of Bcl-2 and caspase-1.

    Weigang Zhu;Herman Friedman;Thomas W. Klein

  • Interferon-gamma induction by lipopolysaccharide: dependence on interleukin 2 and macrophages.

    D K Blanchard;J Y Djeu;T W Klein;H Friedman

  • The effect of delta-9-tetrahydrocannabinol and 11-hydroxy-delta-9-tetrahydrocannabinol on T-lymphocyte and B-lymphocyte mitogen responses.

    T. W. Klein;C. A. Newton;R. Widen;H. Friedman

Frequent Co-Authors

Herman Friedman
Herman Friedman University of South Florida
Harvey M. Friedman
Harvey M. Friedman University of Pennsylvania
Julie Y. Djeu
Julie Y. Djeu University of South Florida
Yehia Daaka
Yehia Daaka University of Florida
Andreas Daiber
Andreas Daiber Johannes Gutenberg University of Mainz
Yutaka Kawakami
Yutaka Kawakami International University Of Health And Welfare Atami Hospital
Kevin E. Kip
Kevin E. Kip University of South Florida
Charles E. Cox
Charles E. Cox University of South Florida
Josef Pfeilschifter
Josef Pfeilschifter Goethe University Frankfurt
Hideyo Yamaguchi
Hideyo Yamaguchi Teikyo University

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