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David J. Shapiro

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
9831
World Ranking
12802
National Ranking
5455

David J. Shapiro publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where David J. Shapiro sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 154 publications — 29th percentile

29% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

David J. Shapiro D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where David J. Shapiro sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 59 D-Index — 38th percentile

38% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

David J. Shapiro is a researcher affiliated with the University of Illinois at Urbana-Champaign in the United States. Their work primarily focuses on areas within biochemistry, genetics, molecular biology, and medicine, with a significant emphasis on molecular biology, genetics, cell biology, oncology, and cancer research.

The scientist has contributed to several notable research topics including:

  • Estrogen and related hormone effects
  • Endoplasmic reticulum stress and disease
  • Cholesterol and lipid metabolism
  • Cancer, lipids, and metabolism
  • Cancer, hypoxia, and metabolism
  • Advanced breast cancer therapies
  • Ferroptosis and cancer prognosis

Frequent publication venues for their work include:

  • Cancer Research
  • Journal of the Endocrine Society
  • UNC Libraries
  • Cancer Letters
  • Cancer Immunology Research

Recent research papers authored or co-authored by David J. Shapiro comprise:

  • "27-Hydroxycholesterol acts on myeloid immune cells to induce T cell dysfunction, promoting breast cancer progression" (2020, Cancer Letters)
  • "First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure" (2024, Cell)
  • "A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice" (2021, Science Translational Medicine)
  • "Plasma Membrane Channel TRPM4 Mediates Immunogenic Therapy-Induced Necrosis" (2023, Cancer Research)
  • "Targeting Metabolic Adaptations in the Breast Cancer-Liver Metastatic Niche Using Dietary Approaches to Improve Endocrine Therapy Efficacy" (2022, Molecular Cancer Research)

David J. Shapiro has collaborated frequently with a number of researchers, including:

  • Paul J. Hergenrother
  • Erik R. Nelson
  • Matthew W. Boudreau
  • Chengjian Mao
  • Darjan Duraki

Best Publications

  • A high-efficiency HeLa cell nuclear transcription extract.

    David J. Shapiro;Phillip A. Sharp;Walter W. Wahli;Martha J. Keller

  • Estrogen stabilizes vitellogenin mRNA against cytoplasmic degradation

    Martin L. Brock;David J. Shapiro

  • Regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol synthesis.

    David J. Shapiro;Victor W. Rodwell

  • The immune system and inflammation in breast cancer.

    Xinguo Jiang;David J. Shapiro

  • 3-Hydroxy-3-methylglutaryl-coenzyme A reductase is present in peroxisomes in normal rat liver cells

    Gilbert-A. Keller;Michelle C. Barton;David J. Shapiro;S. J. Singer

  • The Xenopus laevis estrogen receptor: sequence homology with human and avian receptors and identification of multiple estrogen receptor messenger ribonucleic acids.

    Ivan Jeanne Weiler;Denise Lew;David J. Shapiro

  • Insights into hormonal control of messenger RNA stability.

    David A. Nielsen;David J. Shapiro

  • Preparation of capped RNA transcripts using T7 RNA polymerase

    David A. Nielsen;David J. Shapiro

  • Regulation of messenger RNA stability in eukaryotic cells

    David J. Shapiro;John E. Blume;David A. Nielsen

  • Powerful dominant negative mutants of the human estrogen receptor.

    B. A. Ince;Yao Zhuang;C. K. Wrenn;D. J. Shapiro

  • Kinetics of estrogen induction of Xenopus laevis vitellogenin messenger RNA as measured by hybridization to complementary DNA.

    H. J. Baker;David J. Shapiro

  • Influence of whole body protein turnover rate on resting energy expenditure in patients with cancer.

    Kenneth C. H. Fearon;Douglas T. Hansell;Thomas Preston;Jane A. Plumb

  • A highly sensitive, mixed-phase assay for chloramphenicol acetyltransferase activity in transfected cells

    David A. Nielsen;Tsu Chung Chang;David J. Shapiro

  • Vigilin, a ubiquitous protein with 14 K homology domains, is the estrogen-inducible vitellogenin mRNA 3'-untranslated region-binding protein.

    Robin E. Dodson;David J. Shapiro

  • Anticipatory Estrogen Activation of the Unfolded Protein Response is Linked to Cell Proliferation and Poor Survival in Estrogen Receptor α Positive Breast Cancer

    Neal Andruska;Xiaobin Zheng;Xujuan Yang;William G. Helferich

  • Estrogen regulates the absolute rate of transcription of the Xenopus laevis vitellogenin genes.

    M. L. Brock;David J. Shapiro

  • A Novel IMP1 Inhibitor, BTYNB, Targets c-Myc and Inhibits Melanoma and Ovarian Cancer Cell Proliferation

    Lily Mahapatra;Neal Andruska;Chengjian Mao;Jeremy Le

  • Estrogen receptor-dependent and estrogen receptor-independent pathways for tamoxifen and 4-hydroxytamoxifen-induced programmed cell death

    Maria Obrero;David V. Yu;David J. Shapiro

  • HMG-1 stimulates estrogen response element binding by estrogen receptor from stably transfected HeLa cells.

    Cheng Cheng Zhang;Sacha Krieg;David J. Shapiro

  • Activation of the p38 mitogen-activated protein kinase pathway by estrogen or by 4-hydroxytamoxifen is coupled to estrogen receptor-induced apoptosis.

    Cheng Cheng Zhang;David J. Shapiro

Frequent Co-Authors

Benita S. Katzenellenbogen
Benita S. Katzenellenbogen University of Illinois at Urbana-Champaign
Paul J. Hergenrother
Paul J. Hergenrother University of Illinois at Urbana-Champaign
David A. Nielsen
David A. Nielsen Baylor College of Medicine
Michelle Craig Barton
Michelle Craig Barton The University of Texas MD Anderson Cancer Center
William G. Helferich
William G. Helferich University of Illinois at Urbana-Champaign
Elizabeth M. Wilson
Elizabeth M. Wilson University of North Carolina at Chapel Hill
Cheng Cheng Zhang
Cheng Cheng Zhang The University of Texas Southwestern Medical Center
Geoffrey L. Greene
Geoffrey L. Greene University of Chicago
Yoshiaki Ito
Yoshiaki Ito National University of Singapore
Walter Wahli
Walter Wahli University of Lausanne

External Links

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Best Scientists Citing David J. Shapiro

Benita S. Katzenellenbogen

Benita S. Katzenellenbogen

University of Illinois at Urbana-Champaign

Publications: 53

Jamshed R. Tata

Jamshed R. Tata

Medical Research Council

Publications: 29

Antonin de Fougerolles

Antonin de Fougerolles

Alnylam Pharmaceuticals (United States)

Publications: 26

Farzad Pakdel

Farzad Pakdel

University of Rennes

Publications: 23

John A. Katzenellenbogen

John A. Katzenellenbogen

University of Illinois at Urbana-Champaign

Publications: 22

Walter Wahli

Walter Wahli

University of Lausanne

Publications: 22

Jan-Åke Gustafsson

Jan-Åke Gustafsson

University of Houston

Publications: 20

Carolyn M. Klinge

Carolyn M. Klinge

University of Louisville

Publications: 17

Geoffrey L. Greene

Geoffrey L. Greene

University of Chicago

Publications: 15

Dean P. Edwards

Dean P. Edwards

Baylor College of Medicine

Publications: 15

Roscoe O. Brady

Roscoe O. Brady

Beth Israel Deaconess Medical Center

Publications: 14

Gerhart U. Ryffel

Gerhart U. Ryffel

University of Duisburg-Essen

Publications: 13

Taisen Iguchi

Taisen Iguchi

National Institute for Basic Biology

Publications: 12

Donald W. Pfaff

Donald W. Pfaff

Rockefeller University

Publications: 11

Russell Hilf

Russell Hilf

University of Rochester

Publications: 11

Werner Kloas

Werner Kloas

Leibniz Association

Publications: 11

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