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Biology and Biochemistry

D-Index
54
Citations
14645
World Ranking
15420
National Ranking
6436

Overview

William G. Helferich is affiliated with the University of Illinois at Urbana-Champaign in the United States. Their research primarily focuses on the field of Medicine, with key subfields including Health, Toxicology and Mutagenesis, Molecular Biology, Pharmacology, Reproductive Medicine, and Physiology.

The scientist has contributed to several topics, notably:

  • Effects and risks of endocrine disrupting chemicals
  • Pharmacological Effects of Natural Compounds
  • Endometriosis Research and Treatment
  • Gut microbiota and health
  • Diet and metabolism studies
  • Nutritional Studies and Diet
  • Birth, Development, and Health

Frequent publication venues for this researcher include:

  • Scientific Reports
  • Nutrients
  • Hormones and Behavior
  • Molecular Nutrition & Food Research
  • Current Developments in Nutrition

Frequent co-authors collaborating with Helferich are:

  • Sarabjit Kaur
  • Jessica A. Kinkade
  • Jiude Mao
  • A. Katrin Schenk
  • Nathan J. Bivens

Notable recent papers authored include:

  • "Developmental exposure of California mice to endocrine disrupting chemicals and potential effects on the microbiome-gut-brain axis at adulthood," 2020, Scientific Reports
  • "Genistein Reduces the Risk of Local Mammary Cancer Recurrence and Ameliorates Alterations in the Gut Microbiota in the Offspring of Obese Dams," 2021, Nutrients
  • "Disruption of global hypothalamic microRNA (miR) profiles and associated behavioral changes in California mice (Peromyscus californicus) developmentally exposed to endocrine disrupting chemicals," 2020, Hormones and Behavior
  • "Isoliquiritigenin Decreases Bone Resorption and Osteoclast Differentiation," 2022, Molecular Nutrition & Food Research
  • "Author Correction: Developmental exposure of California mice to endocrine disrupting chemicals and potential effects on the microbiome-gut-brain axis at adulthood," 2020, Scientific Reports

Best Publications

  • Immune evasion in cancer: Mechanistic basis and therapeutic strategies

    Dass S. Vinay;Elizabeth P. Ryan;Graham Pawelec;Wamidh H. Talib

  • Broad targeting of resistance to apoptosis in cancer.

    Ramzi M. Mohammad;Irfana Muqbil;Leroy Lowe;Clement Yedjou

  • Estrogenic Effects of Genistein on the Growth of Estrogen Receptor-positive Human Breast Cancer (MCF-7) Cells in Vitro and in Vivo

    Ching Yi Hsieh;Ross C. Santell;Sandra Z. Haslam;William G. Helferich

  • Investigating the optimal size of anticancer nanomedicine

    Li Tang;Xujuan Yang;Qian Yin;Kaimin Cai

  • Equol, a natural estrogenic metabolite from soy isoflavones: convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors alpha and beta.

    Rajeev S Muthyala;Young H Ju;Shubin Sheng;Lee D Williams

  • Tissue invasion and metastasis: Molecular, biological and clinical perspectives.

    Wen Guo Jiang;Andrew James Sanders;M. Katoh;H. Ungefroren

  • Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy

    Karson S. Putt;Grace W. Chen;Jennifer M. Pearson;Joseph S. Sandhorst

  • Cancer prevention and therapy through the modulation of the tumor microenvironment.

    Stephanie C. Casey;Amedeo Amedei;Katia Aquilano;Asfar S. Azmi

  • Physiological concentrations of dietary genistein dose-dependently stimulate growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in athymic nude mice.

    Young H. Ju;Clinton D. Allred;Kimberly F. Allred;Kimberly L. Karko

  • Designing a broad-spectrum integrative approach for cancer prevention and treatment

    Keith I. Block;Charlotte Gyllenhaal;Leroy Lowe;Amedeo Amedei

  • Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition

    Lynnette R. Ferguson;Helen Chen;Andrew R. Collins;Marisa Connell

  • The phytoestrogen genistein induces thymic and immune changes: A human health concern?

    Srikanth Yellayi;Afia Naaz;Melissa A. Szewczykowski;Tomomi Sato;Tomomi Sato

  • Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice

    Young H. Ju;Daniel R. Doerge;Kimberly F. Allred;Clinton D. Allred

  • Dietary genistin stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with genistein

    Clinton D. Allred;Young H. Ju;Kimberly F. Allred;Jongsoo Chang

  • Estrogen Receptors α and β as Determinants of Gene Expression: Influence of Ligand, Dose, and Chromatin Binding

    Edmund C. Chang;Tze Howe Charn;Sung Hee Park;William G Helferich

  • β-Sitosterol, β-Sitosterol Glucoside, and a Mixture of β-Sitosterol and β-Sitosterol Glucoside Modulate the Growth of Estrogen-Responsive Breast Cancer Cells In Vitro and in Ovariectomized Athymic Mice

    Young H. Ju;Laura M. Clausen;Kimberly F. Allred;Anthony L. Almada

  • Phytoestrogens and breast cancer: a complex story.

    W. G. Helferich;J. E. Andrade;M. S. Hoagland

  • Effects of dietary daidzein and its metabolite, equol, at physiological concentrations on the growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in ovariectomized athymic mice

    Young H. Ju;Jodi Fultz;Kimberly F. Allred;Kimberly F. Allred;Daniel R. Doerge

  • Selective Delivery of an Anticancer Drug with Aptamer-Functionalized Liposomes to Breast Cancer Cells in Vitro and in Vivo.

    Hang Xing;Li Tang;Xujuan Yang;Kevin Hwang

  • Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis.

    Rita S. Strakovsky;Huan Wang;Nicki J. Engeseth;Jodi A. Flaws

Frequent Co-Authors

Daniel R. Doerge
Daniel R. Doerge United States Food and Drug Administration
Jodi A. Flaws
Jodi A. Flaws University of Illinois at Urbana-Champaign
Donna L. Korol
Donna L. Korol Syracuse University
Russell T. Turner
Russell T. Turner Oregon State University
John A. Katzenellenbogen
John A. Katzenellenbogen University of Illinois at Urbana-Champaign
Benita S. Katzenellenbogen
Benita S. Katzenellenbogen University of Illinois at Urbana-Champaign
Ikhlas A. Khan
Ikhlas A. Khan University of Mississippi
Amr Amin
Amr Amin University of Sharjah
Katia Aquilano
Katia Aquilano University of Rome Tor Vergata
Jianjun Cheng
Jianjun Cheng University of Illinois at Urbana-Champaign

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