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Chemistry

D-Index
58
Citations
9883
World Ranking
10820
National Ranking
69

Overview

Ronald Micura is affiliated with the University of Innsbruck in Austria and has contributed significantly to the field of Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on Molecular Biology, with key contributions spanning Oncology, Genetics, Organic Chemistry, and Public Health, Environmental and Occupational Health.

The areas of study that define Micura's work include:

  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • RNA Research and Splicing
  • Advanced biosensing and bioanalysis techniques
  • DNA and Nucleic Acid Chemistry
  • Genomics and Chromatin Dynamics
  • Biochemical and Molecular Research

Micura has published extensively, including recent papers such as:

  • Fundamental studies of functional nucleic acids: aptamers, riboswitches, ribozymes and DNAzymes (2020) in Chemical Society Reviews
  • Conformation of sister chromatids in the replicated human genome (2020) in Nature
  • Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol (2022) in Nature Structural & Molecular Biology
  • Time-resolved single-cell RNA-seq using metabolic RNA labelling (2022) in Nature Reviews Methods Primers
  • Machine learning of reverse transcription signatures of variegated polymerases allows mapping and discrimination of methylated purines in limited transcriptomes (2020) in Nucleic Acids Research

The most frequent publication venues where Micura's research appears include:

  • Nucleic Acids Research
  • Angewandte Chemie International Edition
  • Beilstein Journal of Organic Chemistry
  • Angewandte Chemie
  • bioRxiv (Cold Spring Harbor Laboratory)

Collaboration forms a notable aspect of Micura's scientific work. Frequent co-authors include:

  • Laurin Flemmich
  • Alexandra Lusser
  • Raphael Bereiter
  • Kathrin Breuker
  • Eric Ennifar

Best Publications

  • Structural Basis for Discriminative Regulation of Gene Expression by Adenine- and Guanine-Sensing mRNAs

    Alexander Serganov;Yu Ren Yuan;Olga Pikovskaya;Anna Polonskaia

  • Distinct 5-methylcytosine profiles in poly(A) RNA from mouse embryonic stem cells and brain

    Thomas Amort;Dietmar Rieder;Alexandra Wille;Daria Khokhlova-Cubberley

  • Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I.

    Yanli Wang;Janos Ludwig;Christine Schuberth;Marion Goldeck

  • Pyranosyl-RNA: chiroselective self-assembly of base sequences by ligative oligomerization of tetra nucleotide-2′,3′-cyclophosphates (with a commentary concerning the origin of biomolecular homochirality)

    Martin Bolli;Martin Bolli;Ronald Micura;Albert Eschenmoser;Albert Eschenmoser

  • Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation

    Alexander Serganov;Sonja Keiper;Lucy Malinina;Valentina Tereshko

  • Fundamental studies of functional nucleic acids: aptamers, riboswitches, ribozymes and DNAzymes

    Ronald Micura;Claudia Höbartner

  • Ligand-induced folding of the adenosine deaminase A-riboswitch and implications on riboswitch translational control.

    Renate Rieder;Kathrin Lang;Dagmar Graber;Ronald Micura

  • Escherichia coli ribosomal protein S1 unfolds structured mRNAs onto the ribosome for active translation initiation.

    Mélodie Duval;Alexey Korepanov;Alexey Korepanov;Olivier Fuchsbauer;Pierre Fechter

  • Conformational capture of the SAM-II riboswitch

    Andrea Haller;Ulrike Rieder;Michaela Aigner;Scott C Blanchard

  • The dynamic nature of RNA as key to understanding riboswitch mechanisms.

    Andrea Haller;Marie F. Soulière;Ronald Micura

  • Ligand-induced folding of the thiM TPP riboswitch investigated by a structure-based fluorescence spectroscopic approach

    Kathrin Lang;Renate Rieder;Ronald Micura

  • Long non-coding RNAs as targets for cytosine methylation

    Thomas Amort;Marie F. Soulière;Alexandra Wille;Xi-Yu Jia

  • Nascent peptide in the ribosome exit tunnel affects functional properties of the A-site of the peptidyl transferase center.

    Haripriya Ramu;Nora Vázquez-Laslop;Dorota Klepacki;Qing Dai

  • 2'-Azido RNA, a versatile tool for chemical biology: synthesis, X-ray structure, siRNA applications, click labeling.

    Katja Fauster;Markus Hartl;Tobias Santner;Michaela Aigner

  • Folding and ligand recognition of the TPP riboswitch aptamer at single-molecule resolution

    Andrea Haller;Roger B. Altman;Marie F. Soulière;Scott C. Blanchard

  • Small interfering RNAs and their chemical synthesis.

    Ronald Micura

  • Folding of a transcriptionally acting PreQ1 riboswitch

    Ulrike Rieder;Christoph Kreutz;Ronald Micura

  • Methylation of the nucleobases in RNA oligonucleotides mediates duplex–hairpin conversion

    Ronald Micura;Werner Pils;Claudia Höbartner;Karl Grubmayr

  • Chemical synthesis of selenium-modified oligoribonucleotides and their enzymatic ligation leading to an U6 SnRNA stem-loop segment.

    Claudia Höbartner;Ronald Micura

  • Syntheses of RNAs with up to 100 nucleotides containing site-specific 2'-methylseleno labels for use in X-ray crystallography

    Claudia Höbartner;Renate Rieder;Christoph Kreutz;Barbara Puffer

  • Molecular insights into protein synthesis with proline residues.

    Sergey Melnikov;Sergey Melnikov;Justine Mailliot;Justine Mailliot;Lukas Rigger;Sandro Neuner

  • Structural basis for Diels-Alder ribozyme catalyzed carbon-carbon bond formation

    A. Jaschke;A. Serganov;S. Keiper;L. Malinina

Frequent Co-Authors

Dinshaw J. Patel
Dinshaw J. Patel Memorial Sloan Kettering Cancer Center
Heinz Falk
Heinz Falk Johannes Kepler University of Linz
Scott C. Blanchard
Scott C. Blanchard St. Jude Children's Research Hospital
Andreas Marx
Andreas Marx University of Konstanz
Anh Tuân Phan
Anh Tuân Phan Nanyang Technological University
Daniel N. Wilson
Daniel N. Wilson Universität Hamburg
Robert Konrat
Robert Konrat University of Vienna
Alexander S. Mankin
Alexander S. Mankin University of Illinois at Chicago
Eric Westhof
Eric Westhof University of Strasbourg

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