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Chemistry

D-Index
42
Citations
6325
World Ranking
17547
National Ranking
120

Overview

Robert Konrat is affiliated with the Max F. Perutz Laboratories in Austria. Their research primarily centers on biochemistry, genetics, and molecular biology, with a substantial number of publications also covering the field of chemistry. The scientific subfields they focus on include molecular biology, spectroscopy, materials chemistry, organic chemistry, and cellular and molecular neuroscience.

The scientist's research topics include protein structure and dynamics, advanced NMR techniques and applications, enzyme structure and function, NMR spectroscopy and applications, molecular spectroscopy and chirality, computational drug discovery methods, and click chemistry and applications.

Robert Konrat has published several papers in notable scientific journals. Recent publications include:

  • PI by NMR: Probing CH-π Interactions in Protein-Ligand Complexes by NMR Spectroscopy, 2020, Angewandte Chemie International Edition
  • Osteopontin regulates biomimetic calcium phosphate crystallization from disordered mineral layers covering apatite crystallites, 2020, Scientific Reports
  • Membrane Interactions of α-Synuclein Revealed by Multiscale Molecular Dynamics Simulations, Markov State Models, and NMR, 2021, The Journal of Physical Chemistry B
  • Sensitivity-enhanced three-dimensional and carbon-detected two-dimensional NMR of proteins using hyperpolarized water, 2020, Journal of Biomolecular NMR
  • Hyperphosphorylation of Human Osteopontin and Its Impact on Structural Dynamics and Molecular Recognition, 2021, Biochemistry

Frequent coauthors collaborating with Robert Konrat include Roman J. Lichtenecker, Gerald Platzer, Thomas C. Schwarz, Moriz Mayer, and Andreas Beier.

Key publication venues for this scientist encompass the Journal of Biomolecular NMR, bioRxiv (Cold Spring Harbor Laboratory), ChemPhysChem, ChemBioChem, and Research Square.

Best Publications

  • BEST-TROSY experiments for time-efficient sequential resonance assignment of large disordered proteins

    Zsofia Solyom;Melanie Schwarten;Melanie Schwarten;Leonhard Geist;Robert Konrat

  • NMR contributions to structural dynamics studies of intrinsically disordered proteins.

    Robert Konrat

  • Direct Evidence for the Conformational Deformation of the Corrin Ring by the Nucleotide Base in Vitamin B12: Synthesis and Solution Spectroscopic and Crystal Structure Analysis of Co.beta.-Cyanoimidazolylcobamide

    Bernhard Kraeutler;Robert Konrat;Erhard Stupperich;Gerald Faerber

  • Accurate Structural Data Demystify B-12 - High-Resolution Solid-State Structure of Aquocobalamin Perchlorate and Structure-Analysis of the Aquocobalamin Ion in Solution

    Christoph Kratky;Gerald Farber;Karl Gruber;Keith Wilson

  • Structure, function, and dynamics of the dimerization and DNA-binding domain of oncogenic transcription factor v-Myc.

    Wolfgang Fieber;Martin L. Schneider;Theresia Matt;Bernhard Kräutler

  • Direct observation of the dynamic process underlying allosteric signal transmission.

    Sven Brüschweiler;Paul Schanda;Karin Kloiber;Bernhard Brutscher

  • A Multidimensional NMR Experiment for Measurement of the Protein Dihedral Angle ψ Based on Cross-Correlated Relaxation between 1Hα−13Cα Dipolar and 13C‘ (Carbonyl) Chemical Shift Anisotropy Mechanisms

    Daiwen Yang;Robert Konrat;Lewis E. Kay

  • Cooperative unfolding of compact conformations of the intrinsically disordered protein osteopontin.

    Dennis Kurzbach;Gerald Platzer;Thomas C. Schwarz;Morkos A. Henen;Morkos A. Henen

  • Differential multiple-quantum relaxation arising from cross-correlated time-modulation of isotropic chemical shifts.

    Karin Kloiber;Robert Konrat

  • An (H)C(CO)NH-TOCSY pulse scheme for sequential assignment of protonated methyl groups in otherwise deuterated (15)N, (13)C-labeled proteins.

    Kevin H. Gardner;Robert Konrat;Robert Konrat;Michael K. Rosen;Lewis E. Kay

  • High-Affinity Binding of the Staphylococcal HarA Protein to Haptoglobin and Hemoglobin Involves a Domain with an Antiparallel Eight-Stranded β-Barrel Fold

    Agnieszka Dryla;Bernd Hoffmann;Dieter Gelbmann;Carmen Giefing

  • 5-Fluoro pyrimidines: labels to probe DNA and RNA secondary structures by 1D 19F NMR spectroscopy.

    Barbara Puffer;Christoph Kreutz;Ulrike Rieder;Marc-Olivier Ebert

  • Ribose 2'-F labeling : A simple tool for the characterization of RNA secondary structure equilibria by 19F NMR spectroscopy

    Christoph Kreutz;Hanspeter Kählig;Robert Konrat;Ronald Micura

  • The metastasis-associated extracellular matrix protein osteopontin forms transient structure in ligand interaction sites.

    Gerald Platzer;Andreas Schedlbauer;Angela Chemelli;Przemyslaw Ozdowy

  • Identification of the gene encoding alkylglycerol monooxygenase defines a third class of tetrahydrobiopterin-dependent enzymes

    Katrin Watschinger;Markus A. Keller;Georg Golderer;Martin Hermann

  • A general approach for the identification of site-specific RNA binders by 19F NMR spectroscopy: proof of concept.

    Christoph Kreutz;Hanspeter Kählig;Robert Konrat;Ronald Micura

  • The Ambivalent Role of Proline Residues in an Intrinsically Disordered Protein: From Disorder Promoters to Compaction Facilitators.

    Borja Mateos;Clara Conrad-Billroth;Marco Schiavina;Andreas Beier

  • An Organometallic B12-Rotaxane and a B12-Dimer, Relaxed and Loaded Forms of a Molecular Spring

    Renate B. Hannak;Gerald Färber;Robert Konrat;Bernhard Kräutler

  • Simplification of protein NOESY spectra using bioorganic precursor synthesis and NMR spectral editing.

    Roman Lichtenecker;Martin L Ludwiczek;Walther Schmid;Robert Konrat

  • Coherence transfer in nuclear magnetic resonance by selective homonuclear Hartmann-Hahn correlation spectroscopy

    Robert Konrat;Irene Burghardt;Geoffrey Bodenhausen

  • How a protein prepares for B12 binding: structure and dynamics of the B12-binding subunit of glutamate mutase from Clostridium tetanomorphum

    Martin Tollinger;Robert Konrat;Brent H Hilbert;E Neil G Marsh

Frequent Co-Authors

Bernhard Kräutler
Bernhard Kräutler University of Innsbruck
Geoffrey Bodenhausen
Geoffrey Bodenhausen École Normale Supérieure
Ralf Weiskirchen
Ralf Weiskirchen RWTH Aachen University
Bettina Warscheid
Bettina Warscheid University of Freiburg
Paul Schanda
Paul Schanda Institute of Science and Technology Austria
Eliezer Masliah
Eliezer Masliah National Institutes of Health
Karl Gruber
Karl Gruber University of Graz
Dmitri I. Svergun
Dmitri I. Svergun European Bioinformatics Institute
Herbert Lindner
Herbert Lindner Innsbruck Medical University
Roberta Pierattelli
Roberta Pierattelli University of Florence

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