World's Best Scientists 2026 revealed!
Martin Blackledge

Martin Blackledge

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Chemistry
France
2025

D-Index & Metrics

Chemistry

D-Index
82
Citations
21129
World Ranking
3147
National Ranking
82

Research.com Recognitions

  • 2025 - Research.com Chemistry in France Leader Award
  • 2022 - Research.com Chemistry in France Leader Award

Overview

Martin Blackledge is affiliated with Grenoble Alpes University in France and has contributed extensively to the field of Biochemistry, Genetics and Molecular Biology, with a specific focus on Molecular Biology. Their research spans several subfields including Epidemiology, Ecology, Evolution, Behavior and Systematics, Spectroscopy, and Infectious Diseases.

The researcher's work centers on diverse topics such as RNA Research and Splicing, Protein Structure and Dynamics, RNA and protein synthesis mechanisms, RNA modifications and cancer, Enzyme Structure and Function, interferon and immune responses, and Tardigrade Biology and Ecology.

Among their recent publications are:

  • Measles virus nucleo- and phosphoproteins form liquid-like phase-separated compartments that promote nucleocapsid assembly (2020, Science Advances)
  • Conformational Dynamics of Intrinsically Disordered Proteins Regulate Biomolecular Condensate Chemistry (2022, Chemical Reviews)
  • PED in 2021: a major update of the protein ensemble database for intrinsically disordered proteins (2020, Nucleic Acids Research)
  • NMR Provides Unique Insight into the Functional Dynamics and Interactions of Intrinsically Disordered Proteins (2022, Chemical Reviews)
  • The intrinsically disordered SARS-CoV-2 nucleoprotein in dynamic complex with its viral partner nsp3a (2022, Science Advances)

Frequent co-authors in Blackledge's research include Damien Maurin, Nicola Salvi, Malene Ringkjøbing Jensen, Aldo R. Camacho-Zarco, and Serafima Guseva.

Their work has been regularly published in several venues, notably bioRxiv (Cold Spring Harbor Laboratory), Journal of the American Chemical Society, Nature Communications, Science Advances, and Proceedings of the National Academy of Sciences.

Best Publications

  • Structural Characterization of Flexible Proteins Using Small-Angle X-ray Scattering

    Pau Bernado;Efstratios Mylonas;Maxim V. Petoukhov;Martin Blackledge

  • Efficient analysis of macromolecular rotational diffusion from heteronuclear relaxation data.

    Patrice Dosset;Jean-Christophe Hus;Martin Blackledge;Dominique Marion

  • A structural model for unfolded proteins from residual dipolar couplings and small-angle x-ray scattering

    Pau Bernadó;Laurence Blanchard;Peter Timmins;Dominique Marion

  • Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain

    Mark Wells;Henning Tidow;Trevor J. Rutherford;Phineus Markwick

  • Flexible-meccano

    Valéry Ozenne;Frédéric Bauer;Loïc Salmon;Jie-rong Huang

  • Targeting the disordered C-terminus of PTP1B with an allosteric inhibitor

    Navasona Krishnan;Dorothy Koveal;Daniel H Miller;Bin Xue

  • NMR characterization of long-range order in intrinsically disordered proteins.

    Loïc Salmon;Gabrielle Nodet;Valéry Ozenne;Guowei Yin

  • Recent progress in the study of biomolecular structure and dynamics in solution from residual dipolar couplings

    Martin Blackledge

  • Exploring free-energy landscapes of intrinsically disordered proteins at atomic resolution using NMR spectroscopy.

    Malene Ringkjøbing Jensen;Markus Zweckstetter;Jie Rong Huang;Jie Rong Huang;Martin Blackledge

  • What's in a name? Why these proteins are intrinsically disordered: Why these proteins are intrinsically disordered.

    A Keith Dunker;M Madan Babu;Elisar Barbar;Martin Blackledge

  • Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors

    Sigrid Milles;Davide Mercadante;Iker Valle Aramburu;Malene Ringkjøbing Jensen;Malene Ringkjøbing Jensen

  • A novel interactive tool for rigid-body modeling of multi-domain macromolecules using residual dipolar couplings.

    Patrice Dosset;Jean-Christophe Hus;Dominique Marion;Martin Blackledge

  • Defining Long-Range Order and Local Disorder in Native α-Synuclein Using Residual Dipolar Couplings

    Pau Bernado;Carlos W. Bertoncini;Christian Griesinger;Markus Zweckstetter

  • Direct observation of hierarchical protein dynamics

    Józef R. Lewandowski;Meghan E. Halse;Martin Blackledge;Lyndon Emsley;Lyndon Emsley

  • Identification of slow correlated motions in proteins using residual dipolar and hydrogen-bond scalar couplings

    Guillaume Bouvignies;Pau Bernadó;Sebastian Meier;Kyuil Cho

  • Describing intrinsically disordered proteins at atomic resolution by NMR.

    Malene Ringkjøbing Jensen;Rob W H Ruigrok;Martin Blackledge

  • Highly populated turn conformations in natively unfolded tau protein identified from residual dipolar couplings and molecular simulation.

    M. D. Mukrasch;P. Markwick;J. Biernat;M. von. Bergen

  • pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins

    Mihaly Varadi;Simone Kosol;Pierre Lebrun;Erica Valentini

  • Domain conformation of tau protein studied by solution small-angle X-ray scattering.

    Efstratios Mylonas;Antje Hascher;Pau Bernadó;Martin Blackledge

  • Quantitative description of backbone conformational sampling of unfolded proteins at amino acid resolution from NMR residual dipolar couplings.

    Gabrielle Nodet;Loïc Salmon;Valéry Ozenne;Sebastian Meier

  • Intrinsic disorder in measles virus nucleocapsids

    Malene Ringkjøbing Jensen;Guillaume Communie;Euripedes Almeida Ribeiro;Nicolas Martinez

Frequent Co-Authors

Pau Bernadó
Pau Bernadó University of Montpellier
Markus Zweckstetter
Markus Zweckstetter German Center for Neurodegenerative Diseases
Rob W.H. Ruigrok
Rob W.H. Ruigrok Grenoble Alpes University
Lyndon Emsley
Lyndon Emsley École Polytechnique Fédérale de Lausanne
Stephan Grzesiek
Stephan Grzesiek University of Basel
Christian Griesinger
Christian Griesinger Max Planck Society
Sebastian Meier
Sebastian Meier Technical University of Denmark
Guy Schoehn
Guy Schoehn Grenoble Alpes University
Jacek Biernat
Jacek Biernat German Center for Neurodegenerative Diseases
Eckhard Mandelkow
Eckhard Mandelkow German Center for Neurodegenerative Diseases

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