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Chemistry

D-Index
50
Citations
9264
World Ranking
14348
National Ranking
1048

Overview

Frank Löhr is affiliated with Goethe University Frankfurt in Germany and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Their research primarily focuses on Molecular Biology, Infectious Diseases, Computational Theory and Mathematics, Epidemiology, and Oncology.

The scientist's main topics of study include:

  • RNA and protein synthesis mechanisms
  • SARS-CoV-2 and COVID-19 Research
  • Computational Drug Discovery Methods
  • Ubiquitin and proteasome pathways
  • Autophagy in Disease and Therapy
  • Viral gastroenteritis research and epidemiology
  • Epigenetics and DNA Methylation

Among the recent papers featuring Frank Löhr's contributions are:

  • Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy, 2020, Nucleic Acids Research
  • Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders, 2021, Journal of Medicinal Chemistry
  • Ubiquitination in the ERAD Process, 2020, International Journal of Molecular Sciences
  • Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications, 2021, Frontiers in Molecular Biosciences
  • p63 uses a switch-like mechanism to set the threshold for induction of apoptosis, 2020, Nature Chemical Biology

Frequent collaborators include Christian Richter, Harald Schwalbe, Volker Dötsch, Boris Fürtig, and Nadide Altincekic.

The following venues have frequently published Frank Löhr's research:

  • Biomolecular NMR Assignments
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • International Journal of Molecular Sciences
  • Angewandte Chemie International Edition

Best Publications

  • Nix is a selective autophagy receptor for mitochondrial clearance

    Ivana Novak;Vladimir Kirkin;David G McEwan;Ji Zhang

  • High level cell-free expression and specific labeling of integral membrane proteins

    Christian Klammt;Frank Löhr;Birgit Schäfer;Winfried Haase

  • Ubiquitin binding mediates the NF-κB inhibitory potential of ABIN proteins

    S. Wagner;I. Carpentier;V. Rogov;M. Kreike

  • Solution NMR structure of proteorhodopsin.

    Sina Reckel;Daniel Gottstein;Jochen Stehle;Frank Löhr

  • Conformational Switches Modulate Protein Interactions in Peptide Antibiotic Synthetases

    Alexander Koglin;Mohammad R. Mofid;Frank Löhr;Birgit Schäfer

  • Cell-free expression as an emerging technique for the large scale production of integral membrane protein

    Christian Klammt;Daniel Schwarz;Frank Löhr;Birgit Schneider

  • The parallel G-quadruplex structure of vertebrate telomeric repeat sequences is not the preferred folding topology under physiological conditions

    Robert Hänsel;Frank Löhr;Silvie Foldynová-Trantírková;Ernst Bamberg

  • Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy.

    Anna Wacker;Julia E. Weigand;Sabine R. Akabayov;Nadide Altincekic

  • Structural and functional analysis of the GABARAP interaction motif (GIM)

    Vladimir V Rogov;Alexandra Stolz;Arvind C Ravichandran;Diana O Rios‐Szwed

  • Structural basis for the selectivity of the external thioesterase of the surfactin synthetase

    Alexander Koglin;Alexander Koglin;Frank Löhr;Frank Bernhard;Vladimir V. Rogov

  • Investigating macromolecules inside cultured and injected cells by in-cell NMR spectroscopy

    Zach Serber;Philipp Selenko;Robert Hänsel;Sina Reckel

  • Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex.

    Susanne Stefer;Simon Reitz;Fei Wang;Klemens Wild

  • Self-consistent 3J coupling analysis for the joint calibration of Karplus coefficients and evaluation of torsion angles.

    Jürgen M. Schmidt;Markus Blümel;Frank Löhr;Heinz Rüterjans

  • Bovine beta-lactoglobulin: interaction studies with palmitic acid.

    L. Ragona;F. Fogolari;L. Zetta;D. M. Pérez

  • Maturation of an Escherichia coli Ribosomal Peptide Antibiotic by ATP-Consuming N−P Bond Formation in Microcin C7

    Rebecca F Roush;Elizabeth M Nolan;Frank Löhr;Christopher T Walsh

  • The structure of the cytochrome p450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography.

    Yoshitaka Hiruma;Mathias A.S. Hass;Yuki Kikui;Wei-Min Liu

  • High-resolution insight into G-overhang architecture.

    Robert Hänsel;Frank Löhr;Lukáš Trantirek;Lukáš Trantirek;Volker Dötsch

  • In‐Cell NMR Spectroscopy

    Unknown

  • Binding of a designed substrate analogue to diisopropyl fluorophosphatase: implications for the phosphotriesterase mechanism.

    Marc-Michael Blum;Frank Löhr;Andre Richardt;Heinz Ruterjans

  • Structural evolution of C-terminal domains in the p53 family.

    Horng Der Ou;Horng Der Ou;Frank Löhr;Vitali Vogel;Werner Mäntele

  • Characterization of the Interaction of GABARAPL-1 with the LIR Motif of NBR1

    Alexis Rozenknop;Vladimir V. Rogov;Natalia Yu. Rogova;Frank Löhr

Frequent Co-Authors

Volker Dötsch
Volker Dötsch Goethe University Frankfurt
Heinz Rüterjans
Heinz Rüterjans Goethe University Frankfurt
Peter Güntert
Peter Güntert ETH Zurich
Harald Schwalbe
Harald Schwalbe Goethe University Frankfurt
Ivan Dikic
Ivan Dikic Goethe University Frankfurt
Stefan Knapp
Stefan Knapp Goethe University Frankfurt
Soichi Wakatsuki
Soichi Wakatsuki Stanford University
Thomas Sommer
Thomas Sommer Max Delbrück Center for Molecular Medicine
Masatsune Kainosho
Masatsune Kainosho Tokyo Metropolitan University
Mohamed A. Marahiel
Mohamed A. Marahiel Philipp University of Marburg

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