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Biology and Biochemistry

D-Index
60
Citations
12232
World Ranking
12007
National Ranking
5152

Overview

Soichi Wakatsuki is affiliated with Stanford University in the United States, contributing extensively to the fields of biochemistry, genetics, and molecular biology. Their research has a strong focus on molecular biology, materials chemistry, genetics, insect science, and structural biology, with a total of 64 publications across these areas.

The scientist's work encompasses several main research topics, including enzyme structure and function, microbial metabolic engineering and bioproduction, bacterial genetics and biotechnology, RNA and protein synthesis mechanisms, advanced electron microscopy techniques and applications, antibiotic resistance in bacteria, and neonatal health and biochemistry.

Wakatsuki's recent significant papers include:

  • Exosomes From Induced Pluripotent Stem Cell-Derived Cardiomyocytes Promote Autophagy for Myocardial Repair (2020), Journal of the American Heart Association
  • Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2 (2023), Nature Communications
  • Time-resolved crystallography captures light-driven DNA repair (2023), Science
  • Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter (2023), Nature Communications
  • Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency (2021), Proceedings of the National Academy of Sciences

Frequent co-authors in Wakatsuki's publications include Hasan DeMİRÇİ, Yasuo Yoshikuni, Bradley B. Tolar, Christopher Francis, and Irimpan I. Mathews. These collaborations reflect a range of expertise contributing to their research output.

The scientist has published predominantly in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • arXiv (Cornell University)
  • Research Square (Research Square)
  • Acta Crystallographica Section A Foundations and Advances

The scope of Wakatsuki's research touches on various aspects of enzyme mechanisms and structural biology, often employing advanced crystallography and electron microscopy techniques. Their work also engages with areas of microbial metabolic pathways and genetic engineering that interface with bioproduction processes and antibiotic resistance studies.

Best Publications

  • Ubiquitin-binding domains — from structures to functions

    Ivan Dikic;Ivan Dikic;Soichi Wakatsuki;Kylie J. Walters

  • Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation

    Simin Rahighi;Simin Rahighi;Fumiyo Ikeda;Masato Kawasaki;Masato Kawasaki;Masato Akutsu;Masato Akutsu;Masato Akutsu

  • PLEKHM1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC3/GABARAP Proteins.

    David G. McEwan;Doris Popovic;Andrea Gubas;Seigo Terawaki;Seigo Terawaki;Seigo Terawaki

  • Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide

    Norio Kudo;Keigo Kumagai;Nario Tomishige;Toshiyuki Yamaji

  • The crystal structure of cyclin A

    NR Brown;Mem Noble;JA Endicott;EF Garman

  • Crystal structure of troponin C in complex with troponin I fragment at 2.3-Å resolution

    Dmitry G. Vassylyev;Soichi Takeda;Soichi Wakatsuki;Kayo Maeda

  • Crystal Structure of the Human Cytosolic Sialidase Neu2: EVIDENCE FOR THE DYNAMIC NATURE OF SUBSTRATE RECOGNITION

    Leonard M.G. Chavas;Leonard M.G. Chavas;Cristina Tringali;Paola Fusi;Bruno Venerando

  • Eap45 in Mammalian ESCRT-II Binds Ubiquitin via a Phosphoinositide-interacting GLUE Domain

    Thomas Slagsvold;Rein Aasland;Satoshi Hirano;Kristi G. Bache

  • Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins.

    Vladimir V. Rogov;Hironori Suzuki;Mija Marinković;Verena Lang

  • Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting.

    Satoshi Hirano;Masato Kawasaki;Hideaki Ura;Ryuichi Kato

  • High-intensity double-pulse X-ray free-electron laser

    A. Marinelli;D. Ratner;A.A. Lutman;J. Turner

  • The linac coherent light source single particle imaging road map

    A. Aquila;A. Aquila;A. Barty;C. Bostedt;S. Boutet

  • Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.

    Irina Artsimovitch;Marina N. Vassylyeva;Dmitri Svetlov;Vladimir Svetlov

  • Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes

    Yasunori Uchida;Junya Hasegawa;Daniel Chinnapen;Takao Inoue

  • Structural basis of transcription inhibition by antibiotic streptolydigin.

    Dmitry Temiakov;Nikolay Zenkin;Marina N. Vassylyeva;Anna Perederina

  • Structural basis for recognition of acidic-cluster dileucine sequence by GGA1

    Tomoo Shiba;Hiroyuki Takatsu;Terukazu Nogi;Naohiro Matsugaki

  • Structural and functional analysis of the GABARAP interaction motif (GIM)

    Vladimir V Rogov;Alexandra Stolz;Arvind C Ravichandran;Diana O Rios‐Szwed

  • Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport.

    Tomoo Shiba;Masato Kawasaki;Hiroyuki Takatsu;Terukazu Nogi;Terukazu Nogi

  • Structural Basis of the Catalytic Reaction Mechanism of Novel 1,2-α-L-Fucosidase from Bifidobacterium bifidum

    Masamichi Nagae;Atsuko Tsuchiya;Takane Katayama;Kenji Yamamoto

  • Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1.

    Tomoo Shiba;Hiroshi Koga;Hye-Won Shin;Masato Kawasaki

Frequent Co-Authors

Ivan Dikic
Ivan Dikic Goethe University Frankfurt
Kazuhisa Nakayama
Kazuhisa Nakayama Kyoto University
Lucy Shapiro
Lucy Shapiro Stanford University
Mikio Kataoka
Mikio Kataoka Nara Institute of Science and Technology
Ken Sato
Ken Sato Gunma University
Koichi Kato
Koichi Kato National Institutes of Natural Sciences
Masatoshi Maki
Masatoshi Maki Nagoya University
Isao Tanaka
Isao Tanaka Hokkaido University
Atsushi Nakagawa
Atsushi Nakagawa Osaka University

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