2026 James H. Hurley: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	102	488	438	273	241	289	53125

Overview

James H. Hurley is affiliated with the University of California, Berkeley in the United States. Their research spans multiple fields, primarily within biochemistry, genetics, and molecular biology, with significant contributions also in medicine. Their work is concentrated in key subfields such as molecular biology, cell biology, epidemiology, physiology, and immunology.

The main topics of James H. Hurley's research include:

Autophagy in Disease and Therapy
Cellular transport and secretion
Calcium signaling and nucleotide metabolism
Endoplasmic Reticulum Stress and Disease
Lysosomal Storage Disorders Research
HIV Research and Treatment
Parkinson's Disease Mechanisms and Treatments

Some of Hurley's recent papers highlight advances in structural and cellular biology, including:

Structure of SARS-CoV-2 ORF8, a rapidly evolving immune evasion protein, 2020, Proceedings of the National Academy of Sciences
Autophagosome biogenesis comes out of the black box, 2021, Nature Cell Biology
Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex, 2023, Nature
Clathrin-associated AP-1 controls termination of STING signalling, 2022, Nature
A PI3K-WIPI2 positive feedback loop allosterically activates LC3 lipidation in autophagy, 2020, The Journal of Cell Biology

Frequent coauthors collaborating with Hurley include:

Xuefeng Ren
Adam L. Yokom
Chunmei Chang
Liv Jensen
Michael Lazarou

Hurley's work has been published in various scientific venues with a focus on both preprints and peer-reviewed journals. Notable publication venues with multiple contributions are:

bioRxiv (Cold Spring Harbor Laboratory)
Biophysical Journal
Proceedings of the National Academy of Sciences
Zenodo (CERN European Organization for Nuclear Research)
Science Advances

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

10661
Citations
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

8488
Citations
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

895
Citations
Molecular mechanism of multivesicular body biogenesis by ESCRT complexes

Thomas Wollert;James H. Hurley

860
Citations
Crystal structure of the Cys2 activator-binding domain of protein kinase Cδ in complex with phorbol ester

Gongyi Zhang;Marcelo G Kazanietz;Peter M Blumberg;James H Hurley

857
Citations
Membrane budding and scission by the ESCRT machinery: it's all in the neck

James H. Hurley;Phyllis I. Hanson

811
Citations
Ubiquitin-binding domains

James H. Hurley;Sangho Lee;Gali Prag

785
Citations
ESCRTs are everywhere

James H Hurley;James H Hurley

738
Citations
Membrane scission by the ESCRT-III complex

Thomas Wollert;Christian Wunder;Jennifer Lippincott-Schwartz;James H. Hurley

720
Citations
The ESCRT complexes: structure and mechanism of a membrane-trafficking network.

James H. Hurley;Scott D. Emr

661
Citations
Structure and lipid transport mechanism of a StAR-related domain.

Yosuke Tsujishita;James H. Hurley

621
Citations
Mechanisms of Autophagy Initiation.

James H. Hurley;Lindsey N. Young

595
Citations
ESCRT complexes and the biogenesis of multivesicular bodies

James H Hurley

547
Citations
Structure of the adenylyl cyclase catalytic core.

Gongyi Zhang;Yu Liu;Arnold E. Ruoho;James H. Hurley

506
Citations
Taxonomy and function of C1 protein kinase C homology domains.

James H. Hurley;Alexandra C. Newton;Peter J. Parker;Peter M. Blumberg

467
Citations
Structural mechanism for sterol sensing and transport by OSBP-related proteins

Young Jun Im;Sumana Raychaudhuri;William A. Prinz;James H. Hurley

458
Citations
Dynamics of endosomal sorting complex required for transport (ESCRT) machinery during cytokinesis and its role in abscission

Natalie Elia;Rachid Sougrat;Tighe A. Spurlin;James H. Hurley

414
Citations
Reverse-topology membrane scission by the ESCRT proteins

Johannes Schöneberg;Il Hyung Lee;Janet H. Iwasa;James H. Hurley;James H. Hurley

406
Citations
Structure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptor.

Yew‐Seng J. Ho;Lisa M. Burden;James H. Hurley

396
Citations
The ESCRT Complexes

James H. Hurley

393
Citations

Frequent Co-Authors

Juan S. Bonifacino National Institutes of Health

Gerhard Hummer Max Planck Society

Roberto Zoncu University of California, Berkeley

Sascha Martens University of Vienna

Rodolfo Ghirlando National Institutes of Health

Boris Zhivotovsky Karolinska Institute

Evelina Gatti Aix-Marseille University

Sergio Lavandero University of Chile

Tamotsu Yoshimori Osaka University

Beth Levine The University of Texas Southwestern Medical Center

External Links

Wikipedia of James H. Hurley Personal website of James H. Hurley

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