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Wesley I. Sundquist

Wesley I. Sundquist

D-Index & Metrics

Biology and Biochemistry

D-Index
93
Citations
36019
World Ranking
2081
National Ranking
1132

Research.com Recognitions

  • 2014 - Member of the National Academy of Sciences
  • 2011 - Fellow of the American Academy of Arts and Sciences

Overview

Wesley I. Sundquist is affiliated with the University of Utah in the United States. Their primary research spans multiple intersecting fields including Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. Within these fields, Sundquist's work focuses particularly on subfields such as Cell Biology, Virology, Molecular Biology, Immunology, and Infectious Diseases.

The scientist has contributed significantly to research topics such as:

  • Cellular transport and secretion
  • HIV Research and Treatment
  • Mosquito-borne diseases and control
  • Cytomegalovirus and herpesvirus research
  • Lysosomal Storage Disorders Research
  • Interferon and immune responses
  • HIV/AIDS drug development and treatment

Notable recent publications by Sundquist include:

  • Clinical targeting of HIV capsid protein with a long-acting small molecule, 2020, Nature
  • Reconstitution and visualization of HIV-1 capsid-dependent replication and integration in vitro, 2020, Science
  • Membrane constriction and thinning by sequential ESCRT-III polymerization, 2020, Nature Structural & Molecular Biology
  • Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission, 2022, eLife
  • Vaccinia virus hijacks ESCRT-mediated multivesicular body formation for virus egress, 2021, Life Science Alliance

Frequent collaborators in Sundquist's research include Douglas R. Mackay, Katharine S. Ullman, John McCullough, Elliott L. Paine, and Lara Rheinemann. These coauthors have contributed across numerous joint publications demonstrating recurring research partnerships.

Key publication venues where Sundquist's work frequently appears are bioRxiv (Cold Spring Harbor Laboratory), eLife, Nature Structural & Molecular Biology, Current Biology, and Nature.

Wesley I. Sundquist has received several recognitions including being named a Member of the National Academy of Sciences in 2014 and a Fellow of the American Academy of Arts and Sciences in 2011.

Best Publications

  • Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding.

    Jennifer E. Garrus;Uta K. von Schwedler;Owen W. Pornillos;Scott G. Morham

  • Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops

    Wesley I. Sundquist;Aaron Klug

  • HIV-1 Assembly, Budding, and Maturation

    Wesley I. Sundquist;Hans Georg Kräusslich

  • The Protein Network of HIV Budding

    Uta K. Von Schwedler;Melissa Stuchell;Barbara Müller;Diane M. Ward

  • Assembly and Analysis of Conical Models for the HIV-1 Core

    Barbie K. Ganser;Su Li;Victor Y. Klishko;John T. Finch

  • Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5α restriction factor

    Matthew Stremlau;Michel Perron;Mark Lee;Yuan Li

  • Crystal Structure of Human Cyclophilin A Bound to the Amino-Terminal Domain of HIV-1 Capsid

    Theresa R Gamble;Felix F Vajdos;Sanghee Yoo;David K Worthylake

  • Global landscape of HIV-human protein complexes

    Stefanie Jäger;Peter Cimermancic;Peter Cimermancic;Natali Gulbahce;Natali Gulbahce;Jeffrey R. Johnson;Jeffrey R. Johnson;Jeffrey R. Johnson

  • Structure of the Carboxyl-Terminal Dimerization Domain of the HIV-1 Capsid Protein

    Theresa R. Gamble;Sanghee Yoo;Felix F. Vajdos;Uta K. von Schwedler

  • Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis

    Eiji Morita;Virginie Sandrin;Hyo Young Chung;Scott G. Morham

  • The structural biology of HIV assembly.

    Barbie K Ganser-Pornillos;Mark Yeager;Mark Yeager;Mark Yeager;Wesley I Sundquist

  • CRYSTAL STRUCTURES OF THE TRIMERIC HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 MATRIX PROTEIN : IMPLICATIONS FOR MEMBRANE ASSOCIATION AND ASSEMBLY

    Christopher P. Hill;David Worthylake;Daniel P. Bancroft;Allyson M. Christensen

  • Image reconstructions of helical assemblies of the HIV-1 CA protein

    Su Li;Christopher P. Hill;Wesley I. Sundquist;John T. Finch

  • Formation of a Human Immunodeficiency Virus Type 1 Core of Optimal Stability Is Crucial for Viral Replication

    Brett M. Forshey;Uta von Schwedler;Wesley I. Sundquist;Christopher Aiken

  • Virus Budding and the ESCRT Pathway

    Jörg Votteler;Wesley I. Sundquist

  • X-Ray Structures of the Hexameric Building Block of the HIV Capsid

    Owen Pornillos;Barbie K. Ganser-Pornillos;Barbie K. Ganser-Pornillos;Brian N. Kelly;Yuanzi Hua

  • Structure of the Amino-Terminal Core Domain of the HIV-1 Capsid Protein

    Rossitza K. Gitti;Brian M. Lee;Jill Walker;Michael F. Summers

  • Functional Surfaces of the Human Immunodeficiency Virus Type 1 Capsid Protein

    Uta K. von Schwedler;Kirsten M. Stray;Jennifer E. Garrus;Wesley I. Sundquist

  • The molecular mechanism of hepcidin-mediated ferroportin down-regulation

    Ivana De Domenico;Diane Mc Vey Ward;Charles Langelier;Michael B. Vaughn

  • ESCRT-III recognition by VPS4 ATPases

    Melissa D. Stuchell-Brereton;Jack J. Skalicky;Collin David Kieffer;Mary Anne Karren

Frequent Co-Authors

Christopher P. Hill
Christopher P. Hill University of Utah
Mark Yeager
Mark Yeager University of Miami
David G. Myszka
David G. Myszka University of Utah
Michael F. Summers
Michael F. Summers University of Maryland, Baltimore County
Howard Robinson
Howard Robinson Brookhaven National Laboratory
Grant J. Jensen
Grant J. Jensen California Institute of Technology
Diane M. Ward
Diane M. Ward University of Utah
Jerry Kaplan
Jerry Kaplan University of Utah
Pamela J. Bjorkman
Pamela J. Bjorkman California Institute of Technology

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