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Winfried Weissenhorn

Winfried Weissenhorn

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
14872
World Ranking
10179
National Ranking
366

Overview

Winfried Weissenhorn is affiliated with Grenoble Alpes University in France and has contributed extensively to the fields of biochemistry, genetics, molecular biology, medicine, immunology, and microbiology. Their research encompasses a variety of subfields such as infectious diseases, molecular biology, virology, immunology, and cell biology.

The scientist has focused on several key topics including HIV research and treatment, SARS-CoV-2 and COVID-19 research, cellular transport and secretion, lipid membrane structure and behavior, RNA and protein synthesis mechanisms, enzyme structure and function, and monoclonal and polyclonal antibodies research.

Winfried Weissenhorn has published multiple papers, some of the recent ones include:

  • Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation, 2020, Nature Communications
  • Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage, 2023, Nature Structural & Molecular Biology
  • The ESCRT-III isoforms CHMP2A and CHMP2B display different effects on membranes upon polymerization, 2021, BMC Biology
  • Neutralizing Antibodies Targeting HIV-1 gp41, 2020, Viruses
  • Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies, 2021, eLife

Frequent co-authors in their work include Delphine Guilligay, Guidenn Sulbarán, Nicola De Franceschi, Wouter H. Roos, and Patricia Bassereau.

The majority of their publications appear in venues such as bioRxiv (Cold Spring Harbor Laboratory), Viruses, Nature Communications, Nature Structural & Molecular Biology, and BMC Biology.

Best Publications

  • Atomic structure of the ectodomain from HIV-1 gp41

    W. Weissenhorn;A. Dessen;S. C. Harrison;S. C. Harrison;J. J. Skehel

  • Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain.

    Winfried Weissenhorn;Andrea Carfí;Kon-Ho Lee;John J. Skehel

  • Analysis of Memory B Cell Responses and Isolation of Novel Monoclonal Antibodies with Neutralizing Breadth from HIV-1-Infected Individuals

    Davide Corti;Johannes P. M. Langedijk;Andreas Hinz;Michael S. Seaman

  • Structural basis for membrane fusion by enveloped viruses

    W Weissenhorn;A Dessen;L J Calder;S C Harrison

  • Helical Structures of ESCRT-III Are Disassembled by VPS4

    Suman Lata;Guy Schoehn;Ankur Jain;Ricardo Pires

  • Crystal Structure of the Rabies Virus Nucleoprotein-RNA Complex

    Aurélie A. V. Albertini;Amy K. Wernimont;Tadeusz Muziol;Raimond B. G. Ravelli

  • Crystal structure of HIV-1 gp41 including both fusion peptide and membrane proximal external regions.

    Victor Buzon;Ganesh Natrajan;David J Schibli;Felix Campelo

  • Lassa Virus Z Protein Is a Matrix Protein Sufficient for the Release of Virus-Like Particles

    Thomas Strecker;Robert Eichler;Jan ter Meulen;Winfried Weissenhorn

  • Structural Basis for Budding by the ESCRT-III Factor CHMP3

    Tadeusz Muzioł;Estela Pineda-Molina;Raimond B. Ravelli;Alessia Zamborlini

  • Virus membrane fusion

    Winfried Weissenhorn;Andreas Hinz;Yves Gaudin

  • Ebola virus matrix protein VP40 interaction with human cellular factors Tsg101 and Nedd4.

    Joanna Timmins;Guy Schoehn;Sylvie Ricard-Blum;Sandra Scianimanico

  • Vesicular release of ebola virus matrix protein VP40.

    Joanna Timmins;Sandra Scianimanico;Guy Schoehn;Winfried Weissenhorn

  • Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements

    Marc Ferrer;Tarun M. Kapoor;Tim Strassmaier;Winfried Weissenhorn;Winfried Weissenhorn

  • In Vitro Dissection of the Membrane and RNP Binding Activities of Influenza Virus M1 Protein

    Florence Baudin;Isabelle Petit;Winfried Weissenhorn;Rob W.H. Ruigrok

  • A soluble domain of the membrane-anchoring chain of influenza virus hemagglutinin (HA2) folds in Escherichia coli into the low-pH-induced conformation.

    Jue Chen;Stephen A. Wharton;Winfried Weissenhorn;Lesley J. Calder

  • Crystal structure of the matrix protein VP40 from Ebola virus

    Andréa Dessen;Viktor Volchkov;Olga Dolnik;Hans‐Dieter Klenk

  • Structural characterization and membrane binding properties of the matrix protein VP40 of Ebola virus.

    Rob W.H Ruigrok;Guy Schoehn;Andréa Dessen;Eric Forest

  • Structural basis for the Golgi membrane recruitment of Sly1p by Sed5p

    Andreas Bracher;Winfried Weissenhorn

  • The ectodomain of HIV-1 env subunit gp41 forms a soluble, alpha-helical, rod-like oligomer in the absence of gp120 and the N-terminal fusion peptide.

    W. Weissenhorn;S. A. Wharton;L. J. Calder;P. L. Earl

  • Oligomerization of type III secretion proteins PopB and PopD precedes pore formation in Pseudomonas.

    Guy Schoehn;Anne Marie Di Guilmi;David Lemaire;Ina Attree

Frequent Co-Authors

Guy Schoehn
Guy Schoehn Grenoble Alpes University
Patricia Bassereau
Patricia Bassereau Institute Curie
Don C. Wiley
Don C. Wiley Harvard University
Heinrich G. Göttlinger
Heinrich G. Göttlinger University of Massachusetts Chan Medical School
Stephen C. Harrison
Stephen C. Harrison Harvard University
Rob W.H. Ruigrok
Rob W.H. Ruigrok Grenoble Alpes University
Andreas Bracher
Andreas Bracher Max Planck Society
Andréa Dessen
Andréa Dessen Brazilian Biosciences National Laboratory
Heinrich Betz
Heinrich Betz Max Planck Society
Hans-Dieter Klenk
Hans-Dieter Klenk Philipp University of Marburg

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