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Microbiology
Germany
2023

D-Index & Metrics

Microbiology

D-Index
128
Citations
58868
World Ranking
86
National Ranking
4

Medicine

D-Index
128
Citations
58740
World Ranking
2720
National Ranking
134

Research.com Recognitions

  • 2023 - Research.com Microbiology in Germany Leader Award
  • 2022 - Research.com Microbiology in Germany Leader Award
  • 2006 - Robert Koch Gold Medal
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Hans-Dieter Klenk was affiliated with Philipp University of Marburg in Germany. Their research primarily focused on Medicine, with significant contributions in Epidemiology, Agronomy and Crop Science, Infectious Diseases, Public Health, Environmental and Occupational Health, and Immunology.

Their work encompassed several main topics, including:

  • Influenza Virus Research Studies
  • Animal Disease Management and Epidemiology
  • Respiratory viral infections research
  • SARS-CoV-2 and COVID-19 Research
  • Mosquito-borne diseases and control
  • Interferon and immune responses

Among their recent papers were:

  • TMPRSS2 and furin are both essential for proteolytic activation and spread of SARS-CoV-2 in human airway epithelial cells and provide promising drug targets (2020, bioRxiv (Cold Spring Harbor Laboratory))
  • Characterization of changes in the hemagglutinin that accompanied the emergence of H3N2/1968 pandemic influenza viruses (2021, PLoS Pathogens)
  • Characterization of changes in the hemagglutinin that accompanied the emergence of H3N2/1968 pandemic influenza viruses (2021, bioRxiv (Cold Spring Harbor Laboratory))
  • New filovirus disease classification and nomenclature (2020, UNC Libraries)

Frequent co-authors in their publications included Johanna West, Tatyana Matrosovich, Jana Beicht, Jan Baumann, and Nancy Mounogou Kouassi.

The scientist published regularly in venues such as bioRxiv (Cold Spring Harbor Laboratory), PLoS Pathogens, and UNC Libraries.

Hans-Dieter Klenk received recognitions including the Robert Koch Gold Medal in 2006 and was a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Identification of a novel coronavirus in patients with severe acute respiratory syndrome.

    Christian Drosten;Stephan Günther;Wolfgang Preiser;Sylvie van der Werf

  • Activation of influenza A viruses by trypsin treatment

    Hans-Dieter Klenk;Rudolf Rott;Michaela Orlich;Jochen Blödorn

  • Human and avian influenza viruses target different cell types in cultures of human airway epithelium

    Mikhail N. Matrosovich;Tatyana Y. Matrosovich;Thomas Gray;Noel A. Roberts

  • Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease.

    A. Stieneke-Gröber;M. Vey;H. Angliker;E. Shaw

  • Functional balance between haemagglutinin and neuraminidase in influenza virus infections

    Ralf Wagner;Mikhail Matrosovich;Mikhail Matrosovich;Hans-Dieter Klenk

  • Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses.

    Steven M. Jones;Heinz Feldmann;Heinz Feldmann;Ute Ströher;Ute Ströher;Joan B. Geisbert

  • Neuraminidase Is Important for the Initiation of Influenza Virus Infection in Human Airway Epithelium

    Mikhail N. Matrosovich;Tatyana Y. Matrosovich;Thomas Gray;Noel A. Roberts

  • The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host

    G. Gabriel;B. Dauber;T. Wolff;Oliver Planz

  • TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells.

    Dorothea Bestle;Miriam Ruth Heindl;Hannah Limburg;Thuy van Lam van

  • Proteolytic cleavage of the viral glycoproteins and its significance for the virulence of Newcastle disease virus.

    Yoshiyuki Nagai;Hans-Dieter Klenk;Rudolf Rott

  • Processing of the Ebola virus glycoprotein by the proprotein convertase furin

    Viktor E. Volchkov;Heinz Feldmann;Valentina A. Volchkova;Hans-Dieter Klenk

  • Host cell proteases controlling virus pathogenicity

    Hans-Dieter Klenk;Wolfgang Garten

  • SARS — beginning to understand a new virus

    Konrad Stadler;Vega Masignani;Markus Eickmann;Stephan Becker

  • The Ebola virus VP35 protein functions as a type I IFN antagonist.

    Christopher F. Basler;Xiuyan Wang;Elke Mühlberger;Victor Volchkov

  • Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gpl60

    Unknown

  • Proteolytic Activation of Influenza Viruses by Serine Proteases TMPRSS2 and HAT from Human Airway Epithelium

    Eva Böttcher;Tatyana Matrosovich;Michaela Beyerle;Hans-Dieter Klenk

  • The Ebola Virus VP35 Protein Inhibits Activation of Interferon Regulatory Factor 3

    Christopher F. Basler;Andrea Mikulasova;Luis Martinez-Sobrido;Jason Paragas

  • Comparison of the Transcription and Replication Strategies of Marburg Virus and Ebola Virus by Using Artificial Replication Systems

    Elke Mühlberger;Michael Weik;Viktor E. Volchkov;Hans-Dieter Klenk

  • New low-viscosity overlay medium for viral plaque assays

    Mikhail Matrosovich;Tatyana Matrosovich;Wolfgang Garten;Hans Dieter Klenk

  • Interaction of Polymerase Subunit PB2 and NP with Importin α1 Is a Determinant of Host Range of Influenza A Virus

    Gülsah Gabriel;Astrid Herwig;Hans Dieter Klenk

  • GP mRNA of Ebola virus is edited by the Ebola virus polymerase and by T7 and vaccinia virus polymerases.

    Viktor E. Volchkov;Stephan Becker;Valentina A. Volchkova;Vladimir A. Ternovoj

Frequent Co-Authors

Wolfgang Garten
Wolfgang Garten Philipp University of Marburg
Mikhail Matrosovich
Mikhail Matrosovich Philipp University of Marburg
Heinz Feldmann
Heinz Feldmann National Institutes of Health
Stephan Becker
Stephan Becker Philipp University of Marburg
Elke Mühlberger
Elke Mühlberger Boston University
Rudolf Rott
Rudolf Rott University of Giessen
Viktor E. Volchkov
Viktor E. Volchkov École Normale Supérieure de Lyon
Markus Eickmann
Markus Eickmann Philipp University of Marburg
Larissa Kolesnikova
Larissa Kolesnikova Philipp University of Marburg
Rudolf Geyer
Rudolf Geyer University of Giessen

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