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62
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Overview

Mikhail Matrosovich is affiliated with Philipp University of Marburg in Germany. Their research primarily focuses on influenza virus studies within the field of Medicine, with significant contributions to Epidemiology, Infectious Diseases, Immunology, and Molecular Biology.

The scientist's recent publications include:

  • Second sialic acid-binding site of influenza A virus neuraminidase: binding receptors for efficient release (2020, FEBS Journal)
  • Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells (2021, Journal of Virology)
  • Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses (2023, PLoS Pathogens)
  • Diversity and Reassortment Rate of Influenza A Viruses in Wild Ducks and Gulls (2021, Viruses)
  • Characterization of changes in the hemagglutinin that accompanied the emergence of H3N2/1968 pandemic influenza viruses (2021, PLoS Pathogens)

Frequent co-authors collaborating with Matrosovich include Alexandra Gambaryan, Ron A. M. Fouchier, Yulia Postnikova, Anastasia Treshchalina, and Elizaveta Boravleva.

The scientist often publishes in venues such as PLoS Pathogens, Viruses, bioRxiv (Cold Spring Harbor Laboratory), FEBS Journal, and the Journal of Virology.

Main areas of study in Matrosovich's work encompass:

  • Influenza Virus Research Studies
  • Respiratory viral infections research
  • Virology and Viral Diseases
  • Animal Disease Management and Epidemiology
  • Immune Response and Inflammation
  • Diabetes and associated disorders
  • HIV Research and Treatment

The body of work reflects a focus on the molecular and epidemiological aspects of influenza viruses, including investigation into hemagglutinin and neuraminidase functions, viral diversity, host-virus interactions, and mutational effects on virus phenotypes. The combination of topics related to immune response and infection pathways indicates an interdisciplinary approach to infectious disease research."

Best Publications

  • Early Alterations of the Receptor-Binding Properties of H1, H2, and H3 Avian Influenza Virus Hemagglutinins after Their Introduction into Mammals

    Mikhail Matrosovich;Alexander Tuzikov;Nikolai Bovin;Alexandra Gambaryan

  • Human and avian influenza viruses target different cell types in cultures of human airway epithelium

    Mikhail N. Matrosovich;Tatyana Y. Matrosovich;Thomas Gray;Noel A. Roberts

  • The Surface Glycoproteins of H5 Influenza Viruses Isolated from Humans, Chickens, and Wild Aquatic Birds Have Distinguishable Properties

    Mikhail Matrosovich;Nannan Zhou;Yoshihiro Kawaoka;Robert Webster;Robert Webster

  • Functional balance between haemagglutinin and neuraminidase in influenza virus infections

    Ralf Wagner;Mikhail Matrosovich;Mikhail Matrosovich;Hans-Dieter Klenk

  • Neuraminidase Is Important for the Initiation of Influenza Virus Infection in Human Airway Epithelium

    Mikhail N. Matrosovich;Tatyana Y. Matrosovich;Thomas Gray;Noel A. Roberts

  • H9N2 Influenza A Viruses from Poultry in Asia Have Human Virus-like Receptor Specificity

    Mikhail N. Matrosovich;Mikhail N. Matrosovich;Scott Krauss;Robert G. Webster

  • Proteolytic Activation of Influenza Viruses by Serine Proteases TMPRSS2 and HAT from Human Airway Epithelium

    Eva Böttcher;Tatyana Matrosovich;Michaela Beyerle;Hans-Dieter Klenk

  • New low-viscosity overlay medium for viral plaque assays

    Mikhail Matrosovich;Tatyana Matrosovich;Wolfgang Garten;Hans Dieter Klenk

  • BALANCED HEMAGGLUTININ AND NEURAMINIDASE ACTIVITIES ARE CRITICAL FOR EFFICIENT REPLICATION OF INFLUENZA A VIRUS

    Lyndon J. Mitnaul;Mikhail N. Matrosovich;Mikhail N. Matrosovich;Maria R. Castrucci;Alexander B. Tuzikov

  • Avian influenza A viruses differ from human viruses by recognition of sialyloligosaccharides and gangliosides and by a higher conservation of the HA receptor-binding site.

    M.N. Matrosovich;A.S. Gambaryan;S. Teneberg;V.E. Piskarev

  • Evidence for Zanamivir Resistance in an Immunocompromised Child Infected with Influenza B Virus

    Larisa V. Gubareva;Mikhail N. Matrosovich;Malcolm K. Brenner;Richard C. Bethell

  • Overexpression of the α-2,6-Sialyltransferase in MDCK Cells Increases Influenza Virus Sensitivity to Neuraminidase Inhibitors

    Mikhail Matrosovich;Tatyana Matrosovich;Jackie Carr;Noel A. Roberts

  • Receptor-binding specificity of pandemic influenza A (H1N1) 2009 virus determined by carbohydrate microarray

    Robert A Childs;Angelina S Palma;Steve Wharton;Tatyana Matrosovich

  • Selection of influenza virus mutants in experimentally infected volunteers treated with oseltamivir.

    Larisa V. Gubareva;Laurent Kaiser;Mikhail N. Matrosovich;Mikhail N. Matrosovich;Yee Soo-Hoo

  • The Role of Influenza A Virus Hemagglutinin Residues 226 and 228 in Receptor Specificity and Host Range Restriction

    Angela Vines;Krisna Wells;Krisna Wells;Mikhail Matrosovich;Maria R. Castrucci

  • Specification of Receptor-Binding Phenotypes of Influenza Virus Isolates from Different Hosts Using Synthetic Sialylglycopolymers: Non-Egg-Adapted Human H1 and H3 Influenza A and Influenza B Viruses Share a Common High Binding Affinity for 6′-Sialyl(N-acetyllactosamine)

    A.S. Gambaryan;A.B. Tuzikov;V.E. Piskarev;S.S. Yamnikova

  • Identification, Characterization, and Natural Selection of Mutations Driving Airborne Transmission of A/H5N1 Virus

    Martin Linster;Sander van Boheemen;Miranda de Graaf;Eefje J.A. Schrauwen

  • Sialic Acid Receptors of Viruses

    Mikhail Matrosovich;Georg Herrler;Hans Dieter Klenk

  • Neuraminidase Inhibitor-Resistant Influenza Viruses May Differ Substantially in Fitness and Transmissibility

    Hui-Ling Yen;Hui-Ling Yen;Louise M. Herlocher;Erich Hoffmann;Mikhail N. Matrosovich

  • Effects of egg-adaptation on the receptor-binding properties of human influenza A and B viruses.

    A.S. Gambaryan;J.S. Robertson;M.N. Matrosovich;M.N. Matrosovich

Frequent Co-Authors

Hans-Dieter Klenk
Hans-Dieter Klenk Philipp University of Marburg
Robert G. Webster
Robert G. Webster St. Jude Children's Research Hospital
Yoshihiro Kawaoka
Yoshihiro Kawaoka University of Tokyo
Nicolai V. Bovin
Nicolai V. Bovin Russian Academy of Sciences
Wolfgang Garten
Wolfgang Garten Philipp University of Marburg
Markus Eickmann
Markus Eickmann Philipp University of Marburg
Philip R. Dormitzer
Philip R. Dormitzer Pfizer (United States)
Stephan Becker
Stephan Becker Philipp University of Marburg
Peter W. Mason
Peter W. Mason Novartis (Switzerland)
Ron A. M. Fouchier
Ron A. M. Fouchier Erasmus University Rotterdam

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