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D-Index & Metrics

Biology and Biochemistry

D-Index
89
Citations
47066
World Ranking
2498
National Ranking
15

Overview

Mikko Hiltunen is affiliated with the University of Eastern Finland in Finland. Their research spans multiple fields within medicine and related disciplines, with a focus on neurological and molecular biology topics.

The main fields of study for Mikko Hiltunen include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

More specifically, their subfields of study consist of:

  • Neurology
  • Molecular Biology
  • Physiology
  • Cellular and Molecular Neuroscience
  • Genetics

The primary research topics covered by their work include:

  • Alzheimer's disease research and treatments
  • Cerebrospinal fluid and hydrocephalus
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Genomics and Rare Diseases
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Dementia and Cognitive Impairment Research

Mikko Hiltunen has contributed to various publications across multiple venues. The most frequent venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Alzheimer s Disease
  • Nature Communications
  • Alzheimer s & Dementia
  • Fluids and Barriers of the CNS

Among recent papers, some notable works are:

  • FinnGen provides genetic insights from a well-phenotyped isolated population, 2023, Nature
  • FinnGen: Unique genetic insights from combining isolated population and national health register data, 2022, bioRxiv (Cold Spring Harbor Laboratory)
  • Characterising the loss-of-function impact of 5' untranslated region variants in 15,708 individuals, 2020, Nature Communications
  • Early Alzheimer's disease pathology in human cortex involves transient cell states, 2023, Cell
  • Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes, 2020, Nature Communications

The scientist often collaborates with frequent co-authors who have contributed to multiple papers with them. These co-authors include:

  • Ville Leinonen
  • Hilkka Soininen
  • Tuomas Rauramaa
  • Jaakko Kaprio
  • Valtteri Julkunen

Best Publications

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Genome-wide association study indentifies variants at CLU and CR1 associated with Alzheimer’s disease

    J Lambert;S Heath;G Even;D Campion

  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

    Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • A structural variation reference for medical and population genetics

    Ryan L Collins;Ryan L Collins;Harrison Brand;Harrison Brand;Konrad J Karczewski;Konrad J Karczewski;Xuefang Zhao;Xuefang Zhao

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • APOE and Alzheimer disease: a major gene with semi-dominant inheritance

    E Genin;D Hannequin;D Wallon;K Sleegers

  • Depletion of GGA3 Stabilizes BACE and Enhances β-Secretase Activity

    Giuseppina Tesco;Young Ho Koh;Eugene L. Kang;Andrew N. Cameron

  • Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome.

    Antero Salminen;Kai Kaarniranta;Anu Kauppinen;Johanna Ojala

  • Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype.

    Antero Salminen;Johanna Ojala;Kai Kaarniranta;Annakaisa Haapasalo

  • Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease

    Stacy Steinberg;Hreinn Stefansson;Thorlakur Jonsson;Hrefna Johannsdottir

  • Altered Insulin Signaling in Alzheimer's Disease Brain - Special Emphasis on PI3K-Akt Pathway.

    Sami Gabbouj;Simo Ryhänen;Mikael Marttinen;Rebekka Wittrahm

  • Lipoprotein-Associated Phospholipase A2, Platelet-Activating Factor Acetylhydrolase, Is Expressed by Macrophages in Human and Rabbit Atherosclerotic Lesions

    Tomi Häkkinen;Jukka S. Luoma;Mikko O. Hiltunen;Colin H. Macphee

  • PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease.

    Minna Oksanen;Andrew J. Petersen;Nikolay Naumenko;Katja Puttonen

  • DNA hypomethylation and methyltransferase expression in atherosclerotic lesions

    Mikko O Hiltunen;Mikko P Turunen;Tomi P Häkkinen;Juha Rutanen

  • A novel Alzheimer disease locus located near the gene encoding tau protein

    G. Jun;C. A. Ibrahim-Verbaas;M. Vronskaya;J-C Lambert;J-C Lambert;J-C Lambert

  • Catheter-Mediated Vascular Endothelial Growth Factor Gene Transfer to Human Coronary Arteries after Angioplasty

    Marja Laitinen;Juha Hartikainen;Mikko O. Hiltunen;Jaakko Eranen

  • Age-Related Macular Degeneration (AMD): Alzheimer's Disease in the Eye?

    Kai Kaarniranta;Antero Salminen;Annakaisa Haapasalo;Hilkka Soininen

  • Family-Based Association between Alzheimer's Disease and Variants in UBQLN1

    Lars Bertram;Mikko Hiltunen;Michele Parkinson;Martin Ingelsson

  • Hypermethylation of the APC (adenomatous polyposis coli) gene promoter region in human colorectal carcinoma

    Mikko O. Hiltunen;Leena Alhonen;Jari Koistinaho;Sanna Myöhänen

Frequent Co-Authors

Hilkka Soininen
Hilkka Soininen University of Eastern Finland
Seppo Ylä-Herttuala
Seppo Ylä-Herttuala University of Eastern Finland
Irina Alafuzoff
Irina Alafuzoff Uppsala University
Arto Mannermaa
Arto Mannermaa University of Eastern Finland
Sanna-Kaisa Herukka
Sanna-Kaisa Herukka University of Eastern Finland
Heikki Tanila
Heikki Tanila University of Eastern Finland
Mitja I. Kurki
Mitja I. Kurki Broad Institute
Benjamin Grenier-Boley
Benjamin Grenier-Boley Institut Pasteur
Vincent Chouraki
Vincent Chouraki University of Lille

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