D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 68 Citations 23,943 284 World Ranking 4847 National Ranking 39

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Enzyme

Mikko Hiltunen mainly investigates Genetics, Disease, Genome-wide association study, Alzheimer's disease and Pathology. Many of his studies involve connections with topics such as Apolipoprotein E and Genetics. His research in Apolipoprotein E intersects with topics in Odds ratio, Allele and Single-nucleotide polymorphism, Genetic association, Genotype.

His research in Genome-wide association study focuses on subjects like Case-control study, which are connected to Late onset, Molecular genetics and Human genetics. His work focuses on many connections between Alzheimer's disease and other disciplines, such as Dementia, that overlap with his field of interest in Amyloid, Brain biopsy, Biopsy and Lumbar. His biological study spans a wide range of topics, including SORL1 and Age of onset.

His most cited work include:

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease (2614 citations)
  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease (1387 citations)
  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease (1242 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Internal medicine, Disease, Genetics, Endocrinology and Alzheimer's disease. His Internal medicine research incorporates themes from Oncology and Cardiology. His Disease study incorporates themes from Immunology, Pathogenesis, Bioinformatics, Neuroscience and Cohort.

His study in Genetics concentrates on Haplotype, Single-nucleotide polymorphism, Genotype, Allele and Gene. The study incorporates disciplines such as Odds ratio and Preeclampsia in addition to Genotype. His Alzheimer's disease research is multidisciplinary, incorporating elements of Genome-wide association study and Degenerative disease.

He most often published in these fields:

  • Internal medicine (27.54%)
  • Disease (21.97%)
  • Genetics (21.64%)

What were the highlights of his more recent work (between 2018-2021)?

  • Internal medicine (27.54%)
  • Disease (21.97%)
  • Microglia (4.26%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Internal medicine, Disease, Microglia, Cell biology and Normal pressure hydrocephalus. His studies in Internal medicine integrate themes in fields like Endocrinology and Cardiology. His studies deal with areas such as Stage, Computational biology and Gene as well as Disease.

His research on Gene concerns the broader Genetics. In general Microglia, his work in TREM2 is often linked to Wild type linking many areas of study. His Cell biology research includes elements of Autophagy, Cell, Cell type and Neuroinflammation.

Between 2018 and 2021, his most popular works were:

  • Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation (93 citations)
  • Altered Insulin Signaling in Alzheimer's Disease Brain - Special Emphasis on PI3K-Akt Pathway. (47 citations)
  • BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation. (23 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Enzyme

His primary areas of study are Internal medicine, Disease, Cell biology, Gene and Microglia. In his study, Signal transduction is inextricably linked to Endocrinology, which falls within the broad field of Internal medicine. His Disease research is under the purview of Pathology.

His work deals with themes such as Long-term memory, Cell type and Tauopathy, which intersect with Cell biology. His Gene study integrates concerns from other disciplines, such as Bioinformatics and Amyloid. Mikko Hiltunen interconnects Astrocyte, Prodrug, Dementia, Genetic association and Genetic etiology in the investigation of issues within Microglia.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj.
Nature Genetics (2013)

3630 Citations

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish.
Nature Genetics (2011)

1904 Citations

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi.
PLOS ONE (2014)

1380 Citations

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez.
Nature Genetics (2017)

683 Citations

APOE and Alzheimer disease: a major gene with semi-dominant inheritance

E Genin;D Hannequin;D Wallon;K Sleegers.
Molecular Psychiatry (2011)

614 Citations

Lipoprotein-Associated Phospholipase A2, Platelet-Activating Factor Acetylhydrolase, Is Expressed by Macrophages in Human and Rabbit Atherosclerotic Lesions

Tomi Häkkinen;Jukka S. Luoma;Mikko O. Hiltunen;Colin H. Macphee.
Arteriosclerosis, Thrombosis, and Vascular Biology (1999)

332 Citations

Catheter-Mediated Vascular Endothelial Growth Factor Gene Transfer to Human Coronary Arteries after Angioplasty

Marja Laitinen;Juha Hartikainen;Mikko O. Hiltunen;Jaakko Eranen.
Human Gene Therapy (2000)

314 Citations

Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype.

Antero Salminen;Johanna Ojala;Kai Kaarniranta;Annakaisa Haapasalo.
European Journal of Neuroscience (2011)

306 Citations

Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease

Stacy Steinberg;Hreinn Stefansson;Thorlakur Jonsson;Hrefna Johannsdottir.
Nature Genetics (2015)

298 Citations

DNA hypomethylation and methyltransferase expression in atherosclerotic lesions

Mikko O Hiltunen;Mikko P Turunen;Tomi P Häkkinen;Juha Rutanen.
Vascular Medicine (2002)

297 Citations

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