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Biology and Biochemistry

D-Index
65
Citations
17523
World Ranking
9054
National Ranking
4024

Overview

Heinrich G. Göttlinger is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research primarily focuses on immunology and microbiology, medicine, and biochemistry, genetics, and molecular biology. These fields span across several key subfields including virology, infectious diseases, molecular biology, epidemiology, and cell biology.

The overarching topics in Göttlinger's work center on HIV research and treatment, with specific emphasis on HIV/AIDS drug development and treatment, as well as interventions related to HIV/AIDS. Additional areas of study include CRISPR and genetic engineering, Hepatitis B virus studies, cellular transport and secretion mechanisms, and the complement system in diseases.

Frequent collaborators in Göttlinger's research include:

  • Balaji Olety
  • Paul J. Peters
  • Yuanfei Wu
  • Yoshiko Usami
  • Haiyan Wang

Their published work appears in several recurring scientific venues such as:

  • Science Advances
  • mBio
  • Viruses
  • bioRxiv (Cold Spring Harbor Laboratory)

Notable recent publications in their career include:

  • HIV-1 propagation is highly dependent on basal levels of the restriction factor BST2, 2021, Science Advances
  • AP-2 Adaptor Complex-Dependent Enhancement of HIV-1 Replication by Nef in the Absence of the Nef/AP-2 Targets SERINC5 and CD4, 2023, mBio
  • An Inducible ESCRT-III Inhibition Tool to Control HIV-1 Budding, 2023, Viruses
  • The ectodomain sheddase ADAM10 restricts HIV-1 propagation and is counteracted by Nef, 2025, Science Advances
  • An inducible ESCRT-III inhibition tool to control HIV-1 budding, 2023, bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1

    Heinrich G. Gottlinger;Joseph G. Sodroski;William A. Haseltine

  • AIP1/ALIX Is a Binding Partner for HIV-1 p6 and EIAV p9 Functioning in Virus Budding

    Bettina Strack;Arianna Calistri;Stewart Craig;Elena Popova

  • Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release.

    Heinrich G. Gottlinger;Tatyana Dorfman;Joseph G. Sodroski;William A. Haseltine

  • Functional association of cyclophilin A with HIV-1 virions

    Thali M;Bukovsky A;Kondo E;Rosenwirth B

  • SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef

    Yoshiko Usami;Yuanfei Wu;Heinrich G. Göttlinger

  • Identification of a sequence required for efficient packaging of human immunodeficiency virus type 1 RNA into virions.

    A Lever;H Gottlinger;W Haseltine;J Sodroski

  • A role for ubiquitin ligase recruitment in retrovirus release

    Bettina Strack;Arianna Calistri;Molly A. Accola;Giorgio Palù

  • Efficient particle production by minimal Gag constructs which retain the carboxy-terminal domain of human immunodeficiency virus type 1 capsid-p2 and a late assembly domain.

    Molly A. Accola;Bettina Strack;Heinrich G. Göttlinger

  • Role of the matrix protein in the virion association of the human immunodeficiency virus type 1 envelope glycoprotein.

    T Dorfman;F Mammano;W A Haseltine;H G Göttlinger

  • APOBEC3G Incorporation into Human Immunodeficiency Virus Type 1 Particles

    Véronique Zennou;David Perez-Caballero;Heinrich Göttlinger;Paul D. Bieniasz

  • Helical Structures of ESCRT-III Are Disassembled by VPS4

    Suman Lata;Guy Schoehn;Ankur Jain;Ricardo Pires

  • Mapping of functionally important residues of a cysteine-histidine box in the human immunodeficiency virus type 1 nucleocapsid protein.

    T Dorfman;J Luban;S P Goff;W A Haseltine

  • Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism

    Simone Cowan;Theodora Hatziioannou;Tshaka Cunningham;Mark A. Muesing

  • Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis.

    F Mammano;A Ohagen;S Höglund;H G Göttlinger

  • Efficient HIV-1 replication can occur in the absence of the viral matrix protein

    Heide Reil;Anatoly A. Bukovsky;Hans R. Gelderblom;Heinrich G. Göttlinger

  • Functional domains of the capsid protein of human immunodeficiency virus type 1.

    T Dorfman;A Bukovsky;A Ohagen;S Höglund

  • Structural Basis for Budding by the ESCRT-III Factor CHMP3

    Tadeusz Muzioł;Estela Pineda-Molina;Raimond B. Ravelli;Alessia Zamborlini

  • Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses

    Heinrich G. Gottlinger;Tatyana Dorfman;Eric A. Cohen;William A. Haseltine

  • A Putative α-Helical Structure Which Overlaps the Capsid-p2 Boundary in the Human Immunodeficiency Virus Type 1 Gag Precursor Is Crucial for Viral Particle Assembly

    Molly A. Accola;Stefan Höglund;Heinrich G. Göttlinger

  • Release of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 budding

    Alessia Zamborlini;Yoshiko Usami;Sheli R. Radoshitzky;Elena Popova

Frequent Co-Authors

Joseph Sodroski
Joseph Sodroski Harvard Medical School
Winfried Weissenhorn
Winfried Weissenhorn Grenoble Alpes University
William A. Haseltine
William A. Haseltine Human Genome Sciences (United States)
Andrew M. L. Lever
Andrew M. L. Lever University of Cambridge
Éric A. Cohen
Éric A. Cohen University of Montreal
Giorgio Palù
Giorgio Palù University of Padua
Guy Schoehn
Guy Schoehn Grenoble Alpes University
Bruce D. Walker
Bruce D. Walker Harvard University
Paul D. Bieniasz
Paul D. Bieniasz Rockefeller University
Jeremy Luban
Jeremy Luban University of Massachusetts Chan Medical School

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