What is he best known for?
The fields of study he is best known for:
His primary areas of study are Virology, Virus, Capsid, Reverse transcriptase and Viral protein.
Christopher Aiken has included themes like Virus Integration, Cell culture and Point mutation in his Virology study.
His work on Simian immunodeficiency virus, Murine leukemia virus and Infectivity as part of general Virus study is frequently connected to Pseudotyping, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His work investigates the relationship between Capsid and topics such as Biophysics that intersect with problems in Random hexamer.
His Reverse transcriptase study which covers Virus Uncoating that intersects with Transcription, TRIM5alpha and In vitro.
His research investigates the connection between Viral protein and topics such as Cryo-electron microscopy that intersect with problems in Hydrophobic effect, Capsomere and Crystallography.
His most cited work include:
- Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. (642 citations)
- Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics (534 citations)
- Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics (534 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Capsid, Virology, Cell biology, Virus and Mutant.
His Capsid study combines topics from a wide range of disciplines, such as Reverse transcriptase, Biophysics and Cypa, Cyclophilin A, Molecular biology.
His Virology research is multidisciplinary, incorporating elements of Cell culture and Nuclear transport.
In his study, Protease is strongly linked to Cleavage, which falls under the umbrella field of Cell biology.
In the field of Virus, his study on Murine leukemia virus, Vesicular stomatitis virus and Viral life cycle overlaps with subjects such as Pseudotyping.
His research in Mutant intersects with topics in Mutation, Phenotype, DNA and Cell nucleus.
He most often published in these fields:
- Capsid (57.89%)
- Virology (44.36%)
- Cell biology (34.59%)
What were the highlights of his more recent work (between 2017-2021)?
- Capsid (57.89%)
- Cell biology (34.59%)
- Reverse transcriptase (22.56%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Capsid, Cell biology, Reverse transcriptase, Mutant and Biophysics.
Within the field of Virus and Virology Christopher Aiken studies Capsid.
He interconnects HEK 293 cells, Wild type, In vitro and DNA in the investigation of issues within Cell biology.
He focuses mostly in the field of Reverse transcriptase, narrowing it down to matters related to DNA synthesis and, in some cases, Retrovirus, Endogeny and Viral replication.
Christopher Aiken combines subjects such as Viral life cycle and Viral protein with his study of Mutant.
His work deals with themes such as RNA, Recombinant DNA, Small molecule and Random hexamer, which intersect with Biophysics.
Between 2017 and 2021, his most popular works were:
- Inhibitors of the HIV-1 capsid, a target of opportunity (45 citations)
- PF74 Reinforces the HIV-1 Capsid To Impair Reverse Transcription-Induced Uncoating. (29 citations)
- HIV-1 Engages a Dynein-Dynactin-BICD2 Complex for Infection and Transport to the Nucleus (22 citations)
In his most recent research, the most cited papers focused on:
Christopher Aiken mainly investigates Capsid, Virus, Mutant, Cell biology and Biophysics.
His Capsid study necessitates a more in-depth grasp of Virology.
The various areas that he examines in his Virus study include Reverse transcriptase, Phenotype, Interferon, DNA and Peptide sequence.
His Reverse transcriptase research incorporates themes from Viral life cycle, Viral protein and Recombinant DNA.
His work carried out in the field of Mutant brings together such families of science as RNA, Innate immune system, Small molecule and Cell nucleus.
His Biophysics research includes elements of Cypa, Capsomere, Protein structure and Random hexamer.
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