2023 - Research.com Microbiology in United Kingdom Leader Award
2007 - Fellow of the Royal Society, United Kingdom
Member of the European Molecular Biology Organization (EMBO)
Fellow of The Academy of Medical Sciences, United Kingdom
His main research concerns Virology, Viral replication, APOBEC3G, APOBEC-3G Deaminase and Virus. His Virology research is multidisciplinary, relying on both Cell culture, Gene product and Immune system. His research in Viral replication intersects with topics in Retrovirus, Function, Cell biology, SAMHD1 and Nuclear localization sequence.
His study focuses on the intersection of APOBEC3G and fields such as APOBEC3A with connections in the field of CUL5, Post-translational regulation and Ubiquitin ligase complex. His APOBEC-3G Deaminase study integrates concerns from other disciplines, such as Viral infectivity factor and APOBEC. His study in Virus is interdisciplinary in nature, drawing from both Mutation, Gene, Antibody and Reverse transcriptase.
His primary areas of study are Virology, Virus, Cell biology, Viral replication and Molecular biology. Michael H. Malim focuses mostly in the field of Virology, narrowing it down to matters related to Cell culture and, in some cases, Budding. His Virus research is multidisciplinary, incorporating elements of Visna virus, Antibody and Provirus.
Michael H. Malim has researched Viral replication in several fields, including Retrovirus and Transfection. His work in Molecular biology addresses subjects such as RNA, which are connected to disciplines such as Response element. His studies in APOBEC3G integrate themes in fields like Cytidine, APOBEC and Activation-induced deaminase.
The scientist’s investigation covers issues in Antibody, Cell biology, Serology, Immunology and Internal medicine. His biological study spans a wide range of topics, including Virus, Virology and Antigen. He conducts interdisciplinary study in the fields of Virology and Pandemic through his works.
His Cell biology research includes themes of Interferon, DNA, Deep sequencing, Complementary DNA and Viral replication. He has included themes like Syncytium, Cell fusion and Ion channel in his Viral replication study. His Serology research integrates issues from Infection control, Intensive care medicine, Medical diagnosis and Cohort.
His primary areas of investigation include Cell biology, Serology, Cohort, Immunology and Immune system. His Cell biology study incorporates themes from Interferon, Viral entry and Provirus. His Viral entry study is concerned with Viral replication in general.
In the subject of general Serology, his work in Seroprevalence is often linked to Severe acute respiratory syndrome coronavirus 2, thereby combining diverse domains of study. His work carried out in the field of Immune system brings together such families of science as Mutation, Gene and DNA repair. Michael H. Malim combines subjects such as Innate immune system and Computational biology with his study of Gene.
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Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
Ann M. Sheehy;Nathan C. Gaddis;Jonathan D. Choi;Michael H. Malim;Michael H. Malim.
The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA.
Michael H. Malim;Joachim Hauber;Shu-Yun Le;Jacob V. Maizel.
DNA deamination mediates innate immunity to (retro)viral infection
Michael Malim;Ann Sheehy;Reuben Harris;Kate Bishop.
The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif.
Ann M Sheehy;Nathan C Gaddis;Michael H Malim.
Nature Medicine (2003)
Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-κB control
Zhi-Liang Chu;Timothy A. McKinsey;Lily Liu;Jennifer J. Gentry.
Proceedings of the National Academy of Sciences of the United States of America (1997)
The HIV-1 Rev protein
Victoria W. Pollard;Michael H. Malim.
Annual Review of Microbiology (1998)
Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function
Michael H. Malim;Sabine Böhnlein;Joachim Hauber;Bryan R. Cullen.
Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans.
Jeffrey Seow;Carl Graham;Blair Merrick;Sam Acors.
Nature microbiology (2020)
Human Immunodeficiency Virus Type 1 Spinoculation Enhances Infection through Virus Binding
Una O'Doherty;William J. Swiggard;Michael H. Malim.
Journal of Virology (2000)
HIV-1 Accessory Proteins—Ensuring Viral Survival in a Hostile Environment
Michael H. Malim;Michael Emerman.
Cell Host & Microbe (2008)
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