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Simon Wain-Hobson

Simon Wain-Hobson

D-Index & Metrics

Microbiology

D-Index
74
Citations
22716
World Ranking
1559
National Ranking
89

Research.com Recognitions

  • 2007 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Simon Wain-Hobson is affiliated with the Institut Pasteur in France. Their research primarily spans the fields of Immunology and Microbiology as well as Medicine, with specific focus areas in Immunology, Oncology, Molecular Biology, Virology, and Epidemiology. The scientist's work covers key topics including Immune Cell Function and Interaction, Reproductive System and Pregnancy, HIV Research and Treatment, Systemic Lupus Erythematosus Research, Chronic Lymphocytic Leukemia Research, Monoclonal and Polyclonal Antibodies Research, and Cytokine Signaling Pathways and Interactions.

The scientist has coauthored several papers with frequent collaborators such as MyLinh Duong, Jihyun Park, Henri Bayle, Raphael Ognar, and Vincent Caval. The research output includes publications in a variety of scientific venues. Notable journals and venues where the scientist has published include Blood, Regular and Young Investigator Award Abstracts, Cancer Research, Scientific Reports, and the Journal of Biological Chemistry.

Selected recent papers authored or coauthored by Simon Wain-Hobson include:

  • "Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus" (2021) in Scientific Reports
  • "Engineered Natural Killer Cells Expressing Chimeric Ilt Receptors (CIR) Effectively Target HLA-G Positive AML Tumor Cells" (2023) in Blood
  • "Frame-shifted APOBEC3A encodes two alternative proapoptotic proteins that target the mitochondrial network" (2021) in Journal of Biological Chemistry
  • "Luc Montagnier (1932-2022)" (2022) in Science
  • "251 Targeting HLA-G positive tumors with engineered Natural Killer cells expressing a Chimeric ILT Receptor (CIR)" (2023) in Regular and Young Investigator Award Abstracts

Throughout their career, Simon Wain-Hobson has been recognized with membership in scientific organizations, notably as a Member of the Academia Europaea since 2007 and as a Member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Nucleotide sequence of the AIDS virus, LAV

    Simon Wain-Hobson;Pierre Sonigo;Olivier Danos;Stewart Cole

  • Temporal fluctuations in HIV quasispecies in vivo are not reflected by sequential HIV isolations.

    Andreas Meyerhans;Rémi Cheynier;Jan Albert;Martina Seth

  • AIDS virus-specific cytotoxic T lymphocytes in lung disorders.

    Fernando Plata;Brigitte Autran;Livia Pedroza Martins;Simon Wain-Hobson

  • Genetic variability of the AIDS virus: Nucleotide sequence analysis of two isolates from African patients

    Marc Alizon;Simon Wain-Hobson;Luc Montagnier;Pierre Sonigo

  • DNA recombination during PCR

    Andreas Meyerhans;Jean Pierre Vartanian;Simon Wain-Hobson

  • Nucleotide sequence of the visna lentivirus: relationship to the AIDS virus.

    Pierre Sonigo;Marc Alizon;Katherine Staskus;David Klatzmann

  • Genetic organization of a chimpanzee lentivirus related to HIV-1.

    Thierry Huet;Rémi Cheynier;Andreas Meyerhans;Georges Roelants

  • HIV-1 isolates are rapidly evolving quasispecies: evidence for viral mixtures and preferred nucleotide substitutions.

    M Goodenow;T Huet;W Saurin;S Kwok

  • A novel type of human papillomavirus associated with genital neoplasias.

    Sylvie Beaudenon;Dina Kremsdorf;Odile Croissant;Stefania Jablonska

  • Recombination: Multiply infected spleen cells in HIV patients.

    Andreas Jung;Reinhard Maier;Jean-Pierre Vartanian;Gennady Bocharov

  • Selection, recombination, and G----A hypermutation of human immunodeficiency virus type 1 genomes.

    J P Vartanian;A Meyerhans;B Asjö;S Wain-Hobson

  • Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions.

    Jean-Pierre Vartanian;Denise Guétard;Michel Henry;Simon Wain-Hobson

  • Clonal expansion of human T-cell leukemia virus type I-infected cells in asymptomatic and symptomatic carriers without malignancy.

    E Wattel;J P Vartanian;C Pannetier;S Wain-Hobson

  • Nucleotide sequence of Mason-Pfizer monkey virus: an immunosuppressive D-type retrovirus.

    Pierre Sonigo;Christopher Barker;Eric Hunter;Simon Wain-Hobson

  • Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivo

    Rodolphe Suspène;Denise Guétard;Michel Henry;Peter Sommer

  • Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication

    Marianne Bonvin;François Achermann;Isabell Greeve;Deborah Stroka

  • Cytotoxic T lymphocyte responses in the peripheral blood of children born to human immunodeficiency virus-1-infected mothers.

    Rémi Cheynier;Pierre Langlade-Demoyen;Marie-Rose Marescot;Stephane Blanche

  • HIV and T cell expansion in splenic white pulps is accompanied by infiltration of HIV-specific cytotoxic T lymphocytes

    Rémi Cheynier;Sven Henrichwark;Fabienne Hadida;Eric Pelletier

  • Guidelines for naming nonprimate APOBEC3 genes and proteins.

    Rebecca S. LaRue;Valgerdur Andrésdóttir;Yannick Blanchard;Silvestro G. Conticello

  • Human Retroviruses and AIDS. A compilation and analysis of nucleic acid and amino acid sequences: I--II; III--V

    G. Myers;B. Korber;S. Wain-Hobson;R.F. Smith

  • Virus Dynamics: Mathematical Principles of Immunology and Virology

    Simon Wain-Hobson

Frequent Co-Authors

Luc Montagnier
Luc Montagnier Institut Pasteur
Andreas Meyerhans
Andreas Meyerhans Pompeu Fabra University
Stewart T. Cole
Stewart T. Cole Institut Pasteur
Olivier Danos
Olivier Danos REGENXBIO Inc.
Pierre Tiollais
Pierre Tiollais Institut Pasteur
Raymond A. Dwek
Raymond A. Dwek University of Oxford
Antoine Gessain
Antoine Gessain Institut Pasteur
Anne Dejean
Anne Dejean Institut Pasteur
David Givol
David Givol Weizmann Institute of Science
Eric Oksenhendler
Eric Oksenhendler Université Paris Cité

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