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D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
12510
World Ranking
13776
National Ranking
1078

Overview

Colin Nixon is affiliated with the University of Glasgow in the United Kingdom. Their research spans multiple fields, primarily focusing on biochemistry, genetics, molecular biology, and medicine. Within these broad areas, Nixon has made substantial contributions to molecular biology, oncology, cancer research, immunology, and cell biology.

The scientist's work addresses key topics such as cancer, hypoxia, and metabolism; immune cells in cancer; pancreatic and hepatic oncology research; cell adhesion molecules; cancer immunotherapy and biomarkers; cancer genomics and diagnostics; and cancer cells and metastasis.

Coauthors frequently collaborating with Nixon include Owen J. Sansom, Karen Blyth, Kathryn Gilroy, William Clark, and Andrew D. Campbell.

Nixon has published extensively in a range of venues, with the greatest number of publications appearing in bioRxiv (Cold Spring Harbor Laboratory), followed by Nature Communications, Cancer Research, Research Square (Research Square), and Genes & Development.

The following are selected recent papers authored or coauthored by Colin Nixon, highlighting their research focus and publication record:

  • The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer, 2021, Nature Genetics
  • Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence, 2020, Genes & Development
  • Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer, 2020, Cancer Cell
  • NOTUM from Apc-mutant cells biases clonal competition to initiate cancer, 2021, Nature
  • CXCR2 inhibition enables NASH-HCC immunotherapy, 2022, Gut

Best Publications

  • CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma

    Colin W. Steele;Saadia A. Karim;Joshua D.G. Leach;Peter Bailey

  • p53 status determines the role of autophagy in pancreatic tumour development

    Mathias T. Rosenfeldt;Jim O’Prey;Jennifer P. Morton;Colin Nixon

  • Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.

    Rene Jackstadt;Sander R. van Hooff;Joshua D. Leach;Xabier Cortes-Lavaud

  • The chemokine receptor D6 limits the inflammatory response in vivo

    Thomas Jamieson;Donald N Cook;Robert J B Nibbs;Antal Rot

  • Rab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progression

    Marta A. Dozynkiewicz;Nigel B. Jamieson;Nigel B. Jamieson;Iain MacPherson;Joan Grindlay

  • Mannose impairs tumour growth and enhances chemotherapy

    Pablo Sierra Gonzalez;James O'Prey;Simone Cardaci;Valentin J A Barthet

  • Improving the metabolic fidelity of cancer models with a physiological cell culture medium

    Johan Vande Voorde;Tobias Ackermann;Nadja Pfetzer;David Sumpton

  • Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence

    Maria Grazia Vizioli;Tianhui Liu;Karl N. Miller;Neil A. Robertson

  • Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.

    Simone Cardaci;Liang Zheng;Gillian MacKay;Niels J. F. van den Broek

  • A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression

    Francesca R. Auciello;Vinay Bulusu;Chet Oon;Jacqueline Tait-Mulder

  • Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation

    Vinay Bulusu;Sergey Tumanov;Evdokia Michalopoulou;Niels J. van den Broek

  • Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function.

    Jun-ichi Sakamaki;Simon Wilkinson;Marcel Hahn;Nilgun Tasdemir

  • TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence

    Thomas G. Bird;Thomas G. Bird;Miryam Müller;Luke Boulter;David F. Vincent

  • Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion

    P A J Muller;A G Trinidad;P Timpson;J P Morton

  • TIGAR Is Required for Efficient Intestinal Regeneration and Tumorigenesis

    Eric C. Cheung;Dimitris Athineos;Pearl Lee;Rachel A. Ridgway

  • Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer

    Eric C. Cheung;Gina M. DeNicola;Colin Nixon;Karen Blyth

  • CSF1R+ Macrophages Sustain Pancreatic Tumor Growth through T Cell Suppression and Maintenance of Key Gene Programs that Define the Squamous Subtype.

    Juliana B. Candido;Jennifer P. Morton;Peter Bailey;Andrew D. Campbell

  • Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium

    Steven E. Reid;Emily J. Kay;Lisa J. Neilson;Anne Theres Henze

  • LKB1 Haploinsufficiency Cooperates With Kras to Promote Pancreatic Cancer Through Suppression of p21-Dependent Growth Arrest

    Jennifer P. Morton;Nigel B. Jamieson;Nigel B. Jamieson;Saadia A. Karim;Dimitris Athineos

  • N-WASP coordinates the delivery and F-actin–mediated capture of MT1-MMP at invasive pseudopods

    Xinzi Yu;Tobias Zech;Laura McDonald;Esther Garcia Gonzalez

Frequent Co-Authors

Owen J. Sansom
Owen J. Sansom University of Glasgow
Karen Blyth
Karen Blyth University of Glasgow
Jennifer P. Morton
Jennifer P. Morton University of Glasgow
William C. Clark
William C. Clark Harvard University
Peter D. Adams
Peter D. Adams Sanford Burnham Prebys Medical Discovery Institute
Kevin M. Ryan
Kevin M. Ryan University of Glasgow
Simon T. Barry
Simon T. Barry AstraZeneca (United Kingdom)
Karen H. Vousden
Karen H. Vousden The Francis Crick Institute
Jim C. Norman
Jim C. Norman University of Glasgow
Andrew V. Biankin
Andrew V. Biankin University of Glasgow

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