World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
13597
World Ranking
12454
National Ranking
962

Overview

Karen Blyth is affiliated with the University of Glasgow in the United Kingdom, focusing on research within the broad fields of Biochemistry, Genetics, and Molecular Biology as well as Medicine. Their scholarly contributions span subfields including Molecular Biology, Immunology, Oncology, Cancer Research, and Cell Biology.

Their research encompasses key scientific topics such as Cancer, Hypoxia, and Metabolism; Epigenetics and DNA Methylation; Immune Cell Function and Interaction; Cancer Cells and Metastasis; Cancer-related Molecular Pathways; Immune cells in cancer; and Ubiquitin and proteasome pathways.

The scientist has published extensively in peer-reviewed journals, with frequent contributions to venues like bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Nature Metabolism, Cell Death and Differentiation, and the British Journal of Cancer.

Notable recent papers include:

  • Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy, 2021, Nature Communications
  • Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer, 2020, Cancer Cell
  • Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses, 2020, Cell Reports
  • Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix, 2022, Nature Metabolism
  • Immune-regulated IDO1-dependent tryptophan metabolism is source of one-carbon units for pancreatic cancer and stellate cells, 2021, Molecular Cell

Collaborations are a significant aspect of their work, with frequent co-authors including Colin Nixon, Susan Mason, Dimitris Athineos, Sara Zanivan, and David Sumpton.

Best Publications

  • Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells

    Oliver D. K. Maddocks;Celia R. Berkers;Susan M. Mason;Liang Zheng

  • Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress

    Zachary T. Schug;Barrie Peck;Dylan T. Jones;Qifeng Zhang

  • The runx genes: gain or loss of function in cancer

    Karen Blyth;Ewan R. Cameron;James C. Neil

  • Modulating the therapeutic response of tumours to dietary serine and glycine starvation

    Oliver D. K. Maddocks;Dimitris Athineos;Eric C. Cheung;Pearl Lee

  • Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death

    Gabriel Ichim;Jonathan Lopez;Shafiq U. Ahmed;Nathiya Muthalagu

  • Improving the metabolic fidelity of cancer models with a physiological cell culture medium

    Johan Vande Voorde;Tobias Ackermann;Nadja Pfetzer;David Sumpton

  • Fumarate induces redox-dependent senescence by modifying glutathione metabolism

    Liang Zheng;Simone Cardaci;Livnat Jerby;Elaine D. Mackenzie

  • Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.

    Simone Cardaci;Liang Zheng;Gillian MacKay;Niels J. F. van den Broek

  • Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogene

    M. Stewart;A. Terry;M. Hu;M. O’Hara

  • Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation

    Vinay Bulusu;Sergey Tumanov;Evdokia Michalopoulou;Niels J. van den Broek

  • Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency

    Evangelos Giampazolias;Barbara Zunino;Sandeep Dhayade;Florian Bock

  • CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma.

    Josephine Walton;Julianna Blagih;Darren Ennis;Elaine Leung

  • Gene therapy: X-SCID transgene leukaemogenicity.

    Adrian J. Thrasher;Adrian J. Thrasher;H. Bobby Gaspar;H. Bobby Gaspar;Christopher Baum;Christopher Baum;Ute Modlich

  • TIGAR Is Required for Efficient Intestinal Regeneration and Tumorigenesis

    Eric C. Cheung;Dimitris Athineos;Pearl Lee;Rachel A. Ridgway

  • In vivo models in breast cancer research: progress, challenges and future directions

    Ingunn Holen;Valerie Speirs;Bethny Morrissey;Karen Blyth

  • Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer

    Eric C. Cheung;Gina M. DeNicola;Colin Nixon;Karen Blyth

  • Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy.

    Mylène Tajan;Marc Hennequart;Eric C. Cheung;Fabio Zani

  • Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium

    Steven E. Reid;Emily J. Kay;Lisa J. Neilson;Anne Theres Henze

  • N-WASP coordinates the delivery and F-actin–mediated capture of MT1-MMP at invasive pseudopods

    Xinzi Yu;Tobias Zech;Laura McDonald;Esther Garcia Gonzalez

  • MCL-1 is a prognostic indicator and drug target in breast cancer.

    Kirsteen J. Campbell;Sandeep Dhayade;Nicola Ferrari;Andrew H. Sims

Frequent Co-Authors

James C. Neil
James C. Neil University of Glasgow
Colin Nixon
Colin Nixon University of Glasgow
Owen J. Sansom
Owen J. Sansom University of Glasgow
Karen H. Vousden
Karen H. Vousden The Francis Crick Institute
Stephen W.G. Tait
Stephen W.G. Tait University of Glasgow
Peter D. Adams
Peter D. Adams Sanford Burnham Prebys Medical Discovery Institute
Jennifer P. Morton
Jennifer P. Morton University of Glasgow
Jim C. Norman
Jim C. Norman University of Glasgow
Eyal Gottlieb
Eyal Gottlieb Technion – Israel Institute of Technology

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing a degree in Biology or Biochemistry opens numerous opportunities in healthcare, research, and fitness industries. With the rise of flexible learning, related programs like fitness degrees online make it easier for students to specialize in areas such as exercise science and sports medicine.

For those interested in human movement, kinesiology online programs offer in-depth study of anatomy, physiology, and biomechanics. These programs can lead to careers in physical therapy, rehabilitation, or athletic training.

The healthcare field is evolving rapidly, and some professional pathways now require advanced or specialized credentials. Many students opt for the fastest pmhnp program to quickly become Psychiatric Mental Health Nurse Practitioners. Alternatively, the shortest online nurse practitioner program helps working nurses advance their careers at their own pace.

Exploring these online degrees can lead to rewarding careers in both clinical and non-clinical settings, allowing biology and biochemistry graduates to make a meaningful impact across diverse fields.

Best Scientists Citing Karen Blyth

Trending Scientists

Recently Published Articles