World's Best Scientists 2026 revealed!
Massimiliano Mazzone

Massimiliano Mazzone

D-Index & Metrics

Biology and Biochemistry

D-Index
81
Citations
26360
World Ranking
3848
National Ranking
63

Massimiliano Mazzone publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Massimiliano Mazzone sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 363 publications — 87th percentile

87% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Massimiliano Mazzone D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Massimiliano Mazzone sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 81 D-Index — 81st percentile

81% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Massimiliano Mazzone is affiliated with KU Leuven in Belgium and has notable contributions across several interconnected fields including Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. Their research output covers a broad range of scientific topics, with particular attention to molecular biology, cancer research, immunology, oncology, and pulmonary and respiratory medicine.

The primary topics addressed by their work include:

  • Cancer, Hypoxia, and Metabolism
  • Immune cells in cancer
  • MicroRNA in disease regulation
  • Angiogenesis and VEGF in Cancer
  • Immune Cell Function and Interaction
  • Phagocytosis and Immune Regulation
  • Epigenetics and DNA Methylation

Mazzone has contributed frequently to various publication venues with multiple works appearing particularly in bioRxiv (Cold Spring Harbor Laboratory), Nature Metabolism, Cancer Immunology Research, Science Advances, and Zenodo (CERN European Organization for Nuclear Research).

Collaborative efforts have involved several recurring co-authors, including:

  • Peter Carmeliet
  • Diether Lambrechts
  • Mario Di Matteo
  • Carla Riera-Domingo
  • Guy Eelen

Among recent high-impact papers authored or co-authored by Mazzone are:

  • "An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates" (2020, Cancer Cell)
  • "Mitochondria metabolism sets the species-specific tempo of neuronal development" (2023, Science)
  • "Macrophage-derived glutamine boosts satellite cells and muscle regeneration" (2020, Nature)
  • "Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis" (2020, Cell Metabolism)
  • "PHGDH heterogeneity potentiates cancer cell dissemination and metastasis" (2022, Nature)

The scientist's work integrates complex biological processes such as cellular metabolism, immune system regulation, and cancer microenvironment dynamics. Their role in advancing the understanding of angiogenesis, immune cell function, and cancer progression is reflected in their broad scientific influence.

Massimiliano Mazzone has been recognized as a member of the European Molecular Biology Organization (EMBO), highlighting their engagement with a leading community in molecular biology research.

Best Publications

  • Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene.

    Selma Pennacchietti;Paolo Michieli;Maria Galluzzo;Massimiliano Mazzone

  • Anti-PlGF Inhibits Growth of VEGF(R)-Inhibitor-Resistant Tumors without Affecting Healthy Vessels

    Christian Fischer;Bart Jonckx;Massimiliano Mazzone;Serena Zacchigna

  • Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization

    Massimiliano Mazzone;Massimiliano Mazzone;Daniela Dettori;Daniela Dettori;Daniela Dettori;Rodrigo Leite de Oliveira;Rodrigo Leite de Oliveira;Sonja Loges;Sonja Loges

  • α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming

    Pu-Ste Liu;Haiping Wang;Xiaoyun Li;Tung Chao

  • HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF.

    Charlotte Rolny;Massimiliano Mazzone;Sònia Tugues;Damya Laoui

  • FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?

    Christian Fischer;Massimiliano Mazzone;Massimiliano Mazzone;Bart Jonckx;Bart Jonckx;Peter Carmeliet;Peter Carmeliet

  • Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity

    Andrea Casazza;Damya Laoui;Mathias Wenes;Sabrina Rizzolio

  • Tumour hypoxia causes DNA hypermethylation by reducing TET activity

    Bernard Thienpont;Jessica Steinbacher;Hui Zhao;Flora D’Anna

  • Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

    Julián Aragonés;Martin Schneider;Martin Schneider;Martin Schneider;Katie Van Geyte;Katie Van Geyte;Peter Fraisl;Peter Fraisl

  • Role and Therapeutic Potential of VEGF in the Nervous System

    Carmen Ruiz de Almodovar;Diether Lambrechts;Massimiliano Mazzone;Peter Carmeliet

  • Regulation of Angiogenesis by Oxygen and Metabolism

    Peter Fraisl;Massimiliano Mazzone;Thomas Schmidt;Peter Carmeliet

  • Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited.

    Sonja Loges;Massimiliano Mazzone;Philipp Hohensinner;Peter Carmeliet

  • MET is required for the recruitment of anti-tumoural neutrophils

    Veronica Finisguerra;Giusy Di Conza;Mario Di Matteo;Jens Serneels

  • Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population

    Damya Laoui;Eva Van Overmeire;Giusy Di Conza;Chiara Aldeni

  • Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis

    Mathias Wenes;Min Shang;Mario Di Matteo;Jermaine Goveia

  • The impact of hypoxia on tumor-associated macrophages.

    Anne-Theres Henze;Massimiliano Mazzone

  • Tanycytic VEGF-A boosts blood-hypothalamus barrier plasticity and access of metabolic signals to the arcuate nucleus in response to fasting.

    Fanny Langlet;Barry E. Levin;Barry E. Levin;Serge Luquet;Massimiliano Mazzone

  • An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

    Jermaine Goveia;Katerina Rohlenova;Federico Taverna;Lucas Treps

  • Targeting the tumor and its microenvironment by a dual-function decoy Met receptor.

    Paolo Michieli;Massimiliano Mazzone;Cristina Basilico;Silvia Cavassa

  • Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not?

    Katrien De Bock;Massimiliano Mazzone;Peter Carmeliet

Frequent Co-Authors

Paolo M. Comoglio
Paolo M. Comoglio FIRC Institute of Molecular Oncology
Luca Tamagnone
Luca Tamagnone Catholic University of the Sacred Heart
Jo A. Van Ginderachter
Jo A. Van Ginderachter Vrije Universiteit Brussel
Lena Claesson-Welsh
Lena Claesson-Welsh Uppsala University
Karen Blyth
Karen Blyth University of Glasgow

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