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Bernard Thienpont

Bernard Thienpont

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
16378
World Ranking
17421
National Ranking
291

Overview

Bernard Thienpont is affiliated with KU Leuven in Belgium, with a research focus situated primarily within Biochemistry, Genetics and Molecular Biology as well as Medicine. Their work spans several specialized subfields including Molecular Biology, Cancer Research, Pediatrics, Perinatology and Child Health, Oncology, and Immunology.

The scientist's research covers a range of topics where they have made numerous contributions, especially in areas such as Single-cell and spatial transcriptomics, Epigenetics and DNA Methylation, Cancer Genomics and Diagnostics, Immune cells in cancer, Congenital heart defects research, Cancer, Hypoxia, and Metabolism, and Prenatal Screening and Diagnostics.

Bernard Thienpont has published extensively, with recent notable papers including:

  • Single-Cell Transcriptome Atlas of Murine Endothelial Cells, 2020, published in Cell
  • Methods and applications for single-cell and spatial multi-omics, 2023, published in Nature Reviews Genetics
  • A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling, 2020, published in Cell Research
  • An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates, 2020, published in Cancer Cell
  • Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis, 2020, published in Cell Metabolism

Frequent co-authors collaborating with Bernard Thienpont include Diether Lambrechts, Peter Carmeliet, Guy Eelen, Luc Schoonjans, and Massimiliano Mazzone. This network reflects consistent research partnerships across several projects.

Their research is published in several venues with repeated contributions to bioRxiv (Cold Spring Harbor Laboratory), Nature, Nature Metabolism, Cell Reports, and Cancer Research, indicating an active engagement with both preprint and peer-reviewed scientific literature within prominent journals.

Best Publications

  • Phenotype molding of stromal cells in the lung tumor microenvironment.

    Diether Lambrechts;Els Wauters;Bram Boeckx;Sara Aibar

  • The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells

    Stefanie Seisenberger;Simon Andrews;Felix Krueger;Julia Arand

  • Single-Cell Transcriptome Atlas of Murine Endothelial Cells

    Joanna Kalucka;Laura P.M.H. de Rooij;Jermaine Goveia;Katerina Rohlenova

  • A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain

    Kristofer Davie;Jasper Janssens;Duygu Koldere;Maxime De Waegeneer

  • Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

    Anna Rita Cantelmo;Lena Christin Conradi;Aleksandra Brajic;Jermaine Goveia

  • Tumour hypoxia causes DNA hypermethylation by reducing TET activity

    Bernard Thienpont;Jessica Steinbacher;Hui Zhao;Flora D’Anna

  • A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling.

    Junbin Qian;Siel Olbrecht;Bram Boeckx;Hanne Vos

  • Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing

    Alejandro Sifrim;Marc-Phillip Hitz;Anna Wilsdon;Jeroen Breckpot

  • Emerging patterns of cryptic chromosomal imbalance in patients with idiopathic mental retardation and multiple congenital anomalies: a new series of 140 patients and review of published reports

    B. Menten;N. Maas;B. Thienpont;K. Buysse

  • An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

    Jermaine Goveia;Katerina Rohlenova;Federico Taverna;Lucas Treps

  • The role of fatty acid β-oxidation in lymphangiogenesis

    Brian W. Wong;Xingwu Wang;Annalisa Zecchin;Bernard Thienpont

  • Single-cell chromosomal imbalances detection by array CGH

    Cedric Le Caignec;Claudia Spits;Karen Sermon;Martine De Rycke

  • Submicroscopic chromosomal imbalances detected by array-CGH are a frequent cause of congenital heart defects in selected patients.

    Bernard Thienpont;Luc Mertens;Thomy de Ravel;Benedicte Eyskens

  • Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis

    Joanna Kalucka;Joanna Kalucka;Laura Bierhansl;Nadine Vasconcelos Conchinha;Rindert Missiaen

  • Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis.

    Katerina Rohlenova;Jermaine Goveia;Melissa García-Caballero;Abhishek Subramanian

  • Overcoming immunotherapy resistance in non-small cell lung cancer (NSCLC) - novel approaches and future outlook

    Lena Horvath;Bernard Thienpont;Liyun Zhao;Dominik Wolf

  • Rare Variants in NR2F2 Cause Congenital Heart Defects in Humans

    Saeed Al Turki;Ashok K. Manickaraj;Catherine L. Mercer;Sebastian S. Gerety

  • Lipid availability determines fate of skeletal progenitor cells via SOX9

    Nick van Gastel;Steve Stegen;Guy Eelen;Sandra Schoors

  • HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival

    Steve Stegen;Nick van Gastel;Guy Eelen;Bart Ghesquière

  • A Pan-Cancer Blueprint of the Heterogeneous Tumour Microenvironment Revealed by Single-Cell Profiling

    Junbin Qian;Siel Olbrecht;Bram Boeckx;Hanne Vos

Frequent Co-Authors

Marc Gewillig
Marc Gewillig KU Leuven
Yves Moreau
Yves Moreau KU Leuven
Stein Aerts
Stein Aerts KU Leuven
Geert Mortier
Geert Mortier University of Antwerp
Hiltrud Brauch
Hiltrud Brauch German Cancer Research Center

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