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D-Index & Metrics

Molecular Biology

D-Index
99
Citations
49875
World Ranking
544
National Ranking
300

Research.com Recognitions

  • 2014 - Fellow of the American Academy of Arts and Sciences
  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Geoffrey M. Wahl is affiliated with the Salk Institute for Biological Studies in the United States. Their research focuses primarily on the intersections of biochemistry, genetics, molecular biology, and medicine, with notable contributions in various subfields including molecular biology, cancer research, oncology, surgery, and pulmonary and respiratory medicine.

The scientist's work encompasses several main topics, covering areas such as epigenetics and DNA methylation, cancer biology related to hypoxia and metabolism, RNA modifications in cancer, pancreatic and hepatic oncology, cancer cell behavior and metastasis, ferroptosis linked to cancer prognosis, and pancreatic function with implications for diabetes.

Recent publications by Geoffrey M. Wahl highlight a range of significant biological and oncological questions:

  • Cysteine depletion induces pancreatic tumor ferroptosis in mice, 2020, Science
  • Single-Cell Transcriptomics Reveals a Conserved Metaplasia Program in Pancreatic Injury, 2021, Gastroenterology
  • Structural variants drive context-dependent oncogene activation in cancer, 2022, Nature
  • Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2, 2020, Gastroenterology
  • Stem Cell Determinant SOX9 Promotes Lineage Plasticity and Progression in Basal-like Breast Cancer, 2020, Cell Reports

Frequent collaborators appearing in Geoffrey M. Wahl's publications include Nikki K. Lytle, Kathleen E. DelGiorno, Zhibo Ma, Uri Manor, and Razia F. Naeem. The collaborations span multiple studies and contribute to the depth of investigation in cancer and molecular biology topics.

The publications are often found in prominent venues such as bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, Cancer Research, Gastroenterology, and Nature, reflecting a range of dissemination platforms for early-stage findings as well as peer-reviewed research.

Geoffrey M. Wahl's recognition includes election as a Fellow of the American Academy of Arts and Sciences in 2014 and as a Fellow of the American Association for the Advancement of Science (AAAS) in 2008.

Best Publications

  • Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells.

    Michael F. Clarke;John E. Dick;Peter B. Dirks;Connie J. Eaves

  • Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

    Geoffrey M. Wahl;Michael Stern;George R. Stark

  • Hybridization of nucleic acids immobilized on solid supports

    Judy Meinkoth;Geoffrey Wahl

  • Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

    Franck Toledo;Geoffrey M. Wahl

  • DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts.

    A Di Leonardo;S P Linke;K Clarkin;G M Wahl

  • Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles

    Yuxin Yin;Michael A. Tainsky;Farideh Z. Bischoff;Louise C. Strong

  • Linking the p53 tumour suppressor pathway to somatic cell reprogramming

    Teruhisa Kawamura;Jotaro Suzuki;Jotaro Suzuki;Yunyuan V. Wang;Sergio Menendez

  • MDM2, MDMX and p53 in oncogenesis and cancer therapy.

    Mark Wade;Yao‑Cheng Li;Geoffrey M. Wahl

  • Histone–GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells

    Teru Kanda;Kevin F. Sullivan;Geoffrey M. Wahl

  • Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy

    Mara H. Sherman;Ruth T. Yu;Dannielle D. Engle;Ning Ding

  • c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability.

    Omid Vafa;Mark Wade;Suzanne Kern;Michelle Beeche

  • A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking.

    Jayne M. Stommel;Natalie D. Marchenko;Gretchen S. Jimenez;Ute M. Moll

  • Cysteine depletion induces pancreatic tumor ferroptosis in mice.

    Michael A. Badgley;Daniel M. Kremer;H. Carlo Maurer;H. Carlo Maurer;Kathleen E. DelGiorno

  • Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

    Xu-Rong Jiang;Gretchen Jimenez;Edwin Chang;Maria Frolkis

  • Recombinase-mediated gene activation and site-specific integration in mammalian cells.

    Stephen O'Gorman;Daniel T. Fox;Geoffrey M. Wahl

  • [15] Detection of specific RNAs or specific fragments of DNA by fractionation in gels and transfer to diazobenzyloxymethyl paper

    James C. Alwine;David J. Kemp;Barbara A. Parker;Jakob Reiser

  • A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

    S P Linke;K C Clarkin;A Di Leonardo;A Tsou

  • Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity

    Kristen M. Turner;Viraj Deshpande;Doruk Beyter;Tomoyuki Koga

  • The p53 orchestra: Mdm2 and Mdmx set the tone

    Mark Wade;Yunyuan V. Wang;Geoffrey M. Wahl

  • Patterns of integration of DNA microinjected into cultured mammalian cells: evidence for homologous recombination between injected plasmid DNA molecules.

    K R Folger;E A Wong;G Wahl;M R Capecchi

Frequent Co-Authors

Mark Wade
Mark Wade University of Toronto
George R. Stark
George R. Stark Cleveland Clinic
Leslie E. Orgel
Leslie E. Orgel Salk Institute for Biological Studies
Mirit I. Aladjem
Mirit I. Aladjem National Institutes of Health
Ronald M. Evans
Ronald M. Evans Salk Institute for Biological Studies
Alexandru Almasan
Alexandru Almasan Cleveland Clinic Lerner College of Medicine
Mario R. Capecchi
Mario R. Capecchi University of Utah
Bing Ren
Bing Ren New York Genome Center
Richard L. Klemke
Richard L. Klemke University of California, San Diego
Jian-Hua Mao
Jian-Hua Mao Lawrence Berkeley National Laboratory

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