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Molecular Biology

D-Index
80
Citations
35336
World Ranking
980
National Ranking
521

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Ute M. Moll is affiliated with Stony Brook University in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology, oncology, cancer research, hematology, and radiology.

The scientist has contributed extensively to topics including heat shock proteins research, cancer genomics and diagnostics, acute myeloid leukemia research, DNA repair mechanisms, epigenetics and DNA methylation, cancer-related molecular pathways, and the effects of radiation exposure.

Notable recent publications include:

  • Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers, 2020, Blood
  • The Gain-of-Function p53 R248W Mutant Promotes Migration by STAT3 Deregulation in Human Pancreatic Cancer Cells, 2021, Frontiers in Oncology
  • Suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity, 2021, Nature Communications
  • Dynamics of clonal hematopoiesis under DNA-damaging treatment in patients with ovarian cancer, 2024, Leukemia
  • Epichaperome inhibition targets TP53-mutant AML and AML stem/progenitor cells, 2023, Blood

The scientist frequently publishes in journals such as Blood, bioRxiv (Cold Spring Harbor Laboratory), Leukemia, Cell Death and Differentiation, and Nature Communications.

Collaborative work often involves the following co-authors:

  • Ramona Schulz-Heddergott
  • Jalid Sehouli
  • Isabelle Ray-Coquard
  • Ignace Vergote
  • Elena Ioana Braicu

Ute M. Moll holds membership in the Association of American Physicians. Their contribution to multiple domains within cancer biology and molecular mechanisms is reflected in a considerable body of work across biochemistry, genetics, and medical research.

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • p53 Has a Direct Apoptogenic Role at the Mitochondria

    Motohiro Mihara;Susan H. Erster;Alexander I. Zaika;Oleksi Petrenko

  • Regulation of autophagy by cytoplasmic p53

    Ezgi Tasdemir;M. Chiara Maiuri;M. Chiara Maiuri;M. Chiara Maiuri;Lorenzo Galluzzi;Lorenzo Galluzzi;Lorenzo Galluzzi;Ilio Vitale;Ilio Vitale;Ilio Vitale

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • The MDM2-p53 Interaction

    Ute M Moll;Oleksi Petrenko

  • A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking.

    Jayne M. Stommel;Natalie D. Marchenko;Gretchen S. Jimenez;Ute M. Moll

  • Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

    L. Galluzzi;L. Galluzzi;L. Galluzzi;S. A. Aaronson;J. Abrams;E. S. Alnemri

  • Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion.

    Ute M. Moll;Guy Riou;Arnold J. Levine

  • p53 opens the mitochondrial permeability transition pore to trigger necrosis

    Angelina V. Vaseva;Natalie D. Marchenko;Kyungmin Ji;Stella E. Tsirka

  • The mitochondrial p53 pathway.

    Angelina V. Vaseva;Ute M. Moll

  • Aristolochic acid and the etiology of endemic (Balkan) nephropathy

    Arthur P. Grollman;Shinya Shibutani;Masaaki Moriya;Frederick Miller

  • p63 and p73: roles in development and tumor formation.

    Ute M. Moll;Neda Slade

  • Transcription-independent pro-apoptotic functions of p53.

    Ute M Moll;Sonja Wolff;Daniel Speidel;Wolfgang Deppert

  • p53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest

    Christian J. Braun;Xin Zhang;Irina Savelyeva;Sonja Wolff

  • In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation.

    Susan Erster;Motohiro Mihara;Roger H. Kim;Oleksi Petrenko

  • ΔNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors

    Alex I. Zaika;Neda Slade;Susan H. Erster;Christine Sansome

  • Mr 92,000 Type IV Collagenase Is Increased in Plasma of Patients with Colon Cancer and Breast Cancer

    Stanley Zucker;Rita M. Lysik;Mohammad H. Zarrabi;Ute Moll

  • Cytoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damage.

    U M Moll;A G Ostermeyer;R Haladay;B Winkfield

  • Monoubiquitylation promotes mitochondrial p53 translocation

    Natasha D Marchenko;Sonja Wolff;Susan Erster;Kerstin Becker

  • SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis.

    D Li;N D Marchenko;U M Moll

Frequent Co-Authors

Matthias Dobbelstein
Matthias Dobbelstein University of Göttingen
Lorenzo Galluzzi
Lorenzo Galluzzi Cornell University
Ilio Vitale
Ilio Vitale University of Rome Tor Vergata
Gerry Melino
Gerry Melino University of Rome Tor Vergata
Guido Kroemer
Guido Kroemer Université Paris Cité
Oliver Kepp
Oliver Kepp Institut Gustave Roussy
Gyorgy Szabadkai
Gyorgy Szabadkai University College London
Gustavo Palacios
Gustavo Palacios Icahn School of Medicine at Mount Sinai
Carmen Garrido
Carmen Garrido University of Burgundy
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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