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Molecular Biology

D-Index
58
Citations
33593
World Ranking
2048
National Ranking
166

Overview

Gyorgy Szabadkai is affiliated with University College London in the United Kingdom. Their research primarily focuses on Biochemistry, Genetics, and Molecular Biology, with a notable emphasis on Molecular Biology as a subfield. Other subfields include Cancer Research, Biophysics, Clinical Biochemistry, and Pulmonary and Respiratory Medicine.

The main topics covered by their work involve:

  • Mitochondrial Function and Pathology
  • ATP Synthase and ATPases Research
  • Cancer, Hypoxia, and Metabolism
  • Metabolism and Genetic Disorders
  • RNA modifications and cancer
  • PI3K/AKT/mTOR signaling in cancer
  • Bioinformatics and Genomic Networks

The following recent papers illustrate the scope and focus of their research output:

  • "Mitochondria form contact sites with the nucleus to couple prosurvival retrograde response," 2020, Science Advances
  • "Identification and functional validation of FDA-approved positive and negative modulators of the mitochondrial calcium uniporter," 2021, Cell Reports
  • "Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243 A >G mtDNA mutation," 2021, Nature Communications
  • "Intracellular Chloride Channels Regulate Endothelial Metabolic Reprogramming in Pulmonary Arterial Hypertension," 2022, American Journal of Respiratory Cell and Molecular Biology
  • "PICALM rescues glutamatergic neurotransmission, behavioural function and survival in a Drosophila model of Aβ42 toxicity," 2020, Human Molecular Genetics

Gyorgy Szabadkai has frequently published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science Advances
  • Cancer Research
  • Cell Reports
  • American Journal of Respiratory Cell and Molecular Biology

Collaboration is a significant aspect of their work, with frequent co-authors including:

  • Michael R. Duchen
  • Robert B. Bentham
  • Mariia Yuneva
  • Chih-Yao Chung
  • Kritarth Singh

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels.

    György Szabadkai;Katiuscia Bianchi;Péter Várnai;Diego De Stefani

  • Regulation of autophagy by cytoplasmic p53

    Ezgi Tasdemir;M. Chiara Maiuri;M. Chiara Maiuri;M. Chiara Maiuri;Lorenzo Galluzzi;Lorenzo Galluzzi;Lorenzo Galluzzi;Ilio Vitale;Ilio Vitale;Ilio Vitale

  • Control of Macroautophagy by Calcium, Calmodulin-Dependent Kinase Kinase-β, and Bcl-2

    Maria Høyer-Hansen;Lone Bastholm;Piotr Szyniarowski;Michelangelo Campanella

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • Systems biology of cisplatin resistance: past, present and future

    L Galluzzi;I Vitale;J Michels;C Brenner

  • Calcium and apoptosis: facts and hypotheses.

    Rosario Rizzuto;Paolo Pinton;Davide Ferrari;Mounia Chami

  • Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

    Roberto Bravo;Jose Miguel Vicencio;Jose Miguel Vicencio;Valentina Parra;Rodrigo Troncoso

  • Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase

    Masao Saotome;Dzhamilja Safiulina;György Szabadkai;Sudipto Das

  • Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis.

    György Szabadkai;Anna Maria Simoni;Mounia Chami;Mariusz R. Wieckowski

  • Separating NADH and NADPH fluorescence in live cells and tissues using FLIM.

    Thomas S. Blacker;Zoe F. Mann;Jonathan E. Gale;Mathias Ziegler

  • Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria

    Elena Rapizzi;Paolo Pinton;György Szabadkai;Mariusz R. Wieckowski

  • Mitochondria: the hub of cellular Ca2+ signaling.

    György Szabadkai;Michael R. Duchen

  • Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling

    Clare V Logan;György Szabadkai;György Szabadkai;Jenny A Sharpe;David A Parry

  • Regulation of autophagy by the inositol trisphosphate receptor

    Alfredo Criollo;Maria Chiara Maiuri;Maria Chiara Maiuri;Ezgi Tasdemir;I. Vitale

  • Increased longevity and refractoriness to Ca2+-dependent neurodegeneration in Surf1 knockout mice

    Carlotta Dell'Agnello;Sara Leo;Alessandro Agostino;György Szabadkai

  • The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1

    J M Vicencio;C Ortiz;A Criollo;A W E Jones

  • Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases.

    Carlotta Giorgi;Saverio Marchi;Ines C.M. Simoes;Ziyu Ren

  • Role of SERCA1 Truncated Isoform in the Proapoptotic Calcium Transfer from ER to Mitochondria during ER Stress

    Mounia Chami;Bénédicte Oulès;Bénédicte Oulès;György Szabadkai;György Szabadkai;György Szabadkai;Rachida Tacine;Rachida Tacine

Frequent Co-Authors

Rosario Rizzuto
Rosario Rizzuto University of Padua
Michael R. Duchen
Michael R. Duchen University College London
Guido Kroemer
Guido Kroemer Université Paris Cité
Paolo Pinton
Paolo Pinton University of Ferrara
Michelangelo Campanella
Michelangelo Campanella Royal Veterinary College
Mariusz R. Wieckowski
Mariusz R. Wieckowski Instytut Biologii Doświadczalnej im. Marcelego Nenckiego
Catherine Brenner
Catherine Brenner Université Paris Cité
Lorenzo Galluzzi
Lorenzo Galluzzi Cornell University
Sergio Lavandero
Sergio Lavandero University of Chile
Oliver Kepp
Oliver Kepp Institut Gustave Roussy

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