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Biology and Biochemistry
UK
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
116
Citations
52848
World Ranking
747
National Ranking
40

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2025 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2023 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2007 - Member of Academia Europaea

Overview

Michael R. Duchen is affiliated with University College London in the United Kingdom. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology, Clinical Biochemistry, Cellular and Molecular Neuroscience, Cell Biology, and Biophysics as subfields.

The scientist's main research topics include Mitochondrial Function and Pathology, Metabolism and Genetic Disorders, ATP Synthase and ATPases Research, Endoplasmic Reticulum Stress and Disease, Genetic Neurodegenerative Diseases, Autophagy in Disease and Therapy, and Advanced Fluorescence Microscopy Techniques.

Frequent publication venues for Michael R. Duchen include bioRxiv (Cold Spring Harbor Laboratory), Methods in Molecular Biology, iScience, Autophagy, and Biological Reviews of the Cambridge Philosophical Society.

Their notable recent papers include:

  • The <scp>PERKs</scp> of mitochondria protection during stress: insights for <scp>PERK</scp> modulation in neurodegenerative and metabolic diseases (2022) in Biological reviews/Biological reviews of the Cambridge Philosophical Society
  • MitoSegNet: Easy-to-use Deep Learning Segmentation for Analyzing Mitochondrial Morphology (2020) in iScience
  • The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy (2021) in Autophagy
  • Mitochondria: An Integrative Hub Coordinating Circadian Rhythms, Metabolism, the Microbiome, and Immunity (2020) in Frontiers in Cell and Developmental Biology
  • Excitotoxicity Revisited: Mitochondria on the Verge of a Nervous Breakdown (2021) in Trends in Neurosciences

They have collaborated frequently with several researchers in their field. The most prominent co-authors include Kritarth Singh, Chih-Yao Chung, Gabriel E. Valdebenito, György Szabadkai, and Preethi Sheshadri.

Michael R. Duchen has been recognized as a Member of the Academia Europaea since 2007.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.

    Edward T. Chouchani;Edward T. Chouchani;Victoria R. Pell;Edoardo Gaude;Dunja Aksentijević

  • Mitochondria and calcium: from cell signalling to cell death

    Michael R. Duchen

  • Mitochondria in health and disease: perspectives on a new mitochondrial biology.

    Michael R Duchen

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Cellular and molecular mechanisms of mitochondrial function

    Laura D. Osellame;Thomas S. Blacker;Michael R. Duchen

  • Contributions of Mitochondria to Animal Physiology: From Homeostatic Sensor to Calcium Signalling and Cell Death

    Michael R. Duchen

  • Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation

    Andrey Y. Abramov;Antonella Scorziello;Michael R. Duchen

  • PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-induced Cell Death

    Sonia Gandhi;Alison Wood-Kaczmar;Zhi Yao;Helene Plun-Favreau

  • Unexpected low-dose toxicity of the universal solvent DMSO

    Joana Galvao;Benjamin Davis;Mark Tilley;Eduardo Normando

  • β-Amyloid Peptides Induce Mitochondrial Dysfunction and Oxidative Stress in Astrocytes and Death of Neurons through Activation of NADPH Oxidase

    Andrey Y. Abramov;Laura Canevari;Michael R. Duchen

  • Roles of mitochondria in health and disease.

    Michael R. Duchen

  • Separating NADH and NADPH fluorescence in live cells and tissues using FLIM.

    Thomas S. Blacker;Zoe F. Mann;Jonathan E. Gale;Mathias Ziegler

  • Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia-reperfusion injury.

    Derek J Hausenloy;Michael R Duchen;Derek M Yellon

  • The role of mitochondrial function in the oocyte and embryo.

    Remi Dumollard;Michael R Duchen;John Graham Carroll

  • Maternal diet-induced obesity alters mitochondrial activity and redox status in mouse oocytes and zygotes.

    Natalia Igosheva;Andrey Y. Abramov;Lucilla Poston;Judith J. Eckert

  • The effect of nitric oxide on cell respiration: A key to understanding its role in cell survival or death

    Belén Beltrán;Anthony Mathur;Michael R. Duchen;Jorge D. Erusalimsky

  • Mitochondria: the hub of cellular Ca2+ signaling.

    György Szabadkai;Michael R. Duchen

  • Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing

    Barry Boland;Wai Haung Yu;Olga Corti;Bertrand Mollereau

  • Endothelial Mitochondria Contributing to Vascular Function and Disease

    Sean M. Davidson;Michael R. Duchen

Frequent Co-Authors

Gyorgy Szabadkai
Gyorgy Szabadkai University College London
Andrey Y. Abramov
Andrey Y. Abramov University College London
Michelangelo Campanella
Michelangelo Campanella Royal Veterinary College
Sean M. Davidson
Sean M. Davidson University College London
Derek M. Yellon
Derek M. Yellon University College London
Kenneth Smith
Kenneth Smith University of Nottingham
Francesco Muntoni
Francesco Muntoni University College London
Mervyn Singer
Mervyn Singer University College London
Simon N. Waddington
Simon N. Waddington University College London
Michael P. Murphy
Michael P. Murphy University of Cambridge

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