Andrey Y. Abramov

Overview

Best Publications

• Mechanism of Oxidative Stress in Neurodegeneration

  Sonia Gandhi;Andrey Y. Abramov

  1067
  Citations

• Direct observation of the interconversion of normal and toxic forms of α-synuclein.

  Nunilo Cremades;Samuel I.A. Cohen;Emma Deas;Andrey Y. Abramov

  987
  Citations

• The emerging role of Nrf2 in mitochondrial function.

  Albena T. Dinkova-Kostova;Albena T. Dinkova-Kostova;Andrey Y. Abramov

  862
  Citations

• Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation

  Andrey Y. Abramov;Antonella Scorziello;Michael R. Duchen

  774
  Citations

• PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-induced Cell Death

  Sonia Gandhi;Alison Wood-Kaczmar;Zhi Yao;Helene Plun-Favreau

  770
  Citations

• β-Amyloid Peptides Induce Mitochondrial Dysfunction and Oxidative Stress in Astrocytes and Death of Neurons through Activation of NADPH Oxidase

  Andrey Y. Abramov;Laura Canevari;Michael R. Duchen

  679
  Citations

• Role of mitochondrial ROS in the brain: from physiology to neurodegeneration

  Plamena R. Angelova;Andrey Y. Abramov

  616
  Citations

• Nrf2 regulates ROS production by mitochondria and NADPH oxidase

  Stjepana Kovac;Plamena R. Angelova;Kira M. Holmström;Ying Zhang

  572
  Citations

• PINK1 cleavage at position A103 by the mitochondrial protease PARL

  Emma Deas;Helene Plun-Favreau;Sonia Gandhi;Howard Desmond

  522
  Citations

• Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation

  Serene W. Chen;Srdja Drakulic;Emma Deas;Myriam Ouberai

  514
  Citations

• Maternal diet-induced obesity alters mitochondrial activity and redox status in mouse oocytes and zygotes.

  Natalia Igosheva;Andrey Y. Abramov;Lucilla Poston;Judith J. Eckert

  501
  Citations

• α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease.

  Marthe H. R. Ludtmann;Marthe H. R. Ludtmann;Plamena R. Angelova;Mathew H. Horrocks;Mathew H. Horrocks;Minee L. Choi;Minee L. Choi

  490
  Citations

• Changes in Intracellular Calcium and Glutathione in Astrocytes as the Primary Mechanism of Amyloid Neurotoxicity

  Andrey Y. Abramov;Laura Canevari;Michael R. Duchen

  428
  Citations

• Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration

  Kira M. Holmström;Liam Baird;Ying Zhang;Iain Hargreaves

  411
  Citations

• Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease

  Emma Deas;Nunilo Cremades;Plamena R. Angelova;Marthe H.R. Ludtmann

  403
  Citations

• PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons.

  Alison Wood-Kaczmar;Sonia Gandhi;Zhi Yao;Andrey S. Y. Abramov

  382
  Citations

• Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells

  Alisdair McNeill;Joana Magalhaes;Chengguo Shen;Kai-Yin Chau

  337
  Citations

• The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy

  Victoria S Burchell;David E Nelson;Alvaro Sanchez-Martinez;Alvaro Sanchez-Martinez;Marta Delgado-Camprubi

  336
  Citations

• Expression and modulation of an NADPH oxidase in mammalian astrocytes.

  Andrey Y. Abramov;Jake Jacobson;Frans Wientjes;John Hothersall

  317
  Citations

• Amyloid beta peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase.

  AY Abramov;L Canevari;Duchen

  1
  Citations