D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 70 Citations 20,530 186 World Ranking 1434 National Ranking 29

Research.com Recognitions

Awards & Achievements

The Science Academy Society of Turkey - Bilim Akademisi Neuroscience

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Dopamine

Deniz Kirik mostly deals with Neuroscience, Substantia nigra, Striatum, Dopamine and Parkinson's disease. He interconnects Subventricular zone, Rostral migratory stream and Transplantation in the investigation of issues within Neuroscience. His Substantia nigra research is multidisciplinary, relying on both Glial cell line-derived neurotrophic factor, Alpha-synuclein and Cell biology.

Deniz Kirik has included themes like Lesion, Globus pallidus and Oxidopamine in his Striatum study. His Dopamine research integrates issues from Axoplasmic transport and Neuron. Deniz Kirik has researched Parkinson's disease in several fields, including Cell therapy, Nucleus basalis, Microglia and Immunology.

His most cited work include:

  • Neuronal replacement from endogenous precursors in the adult brain after stroke (2409 citations)
  • Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system. (582 citations)
  • Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat (568 citations)

What are the main themes of his work throughout his whole career to date?

Neuroscience, Dopamine, Parkinson's disease, Striatum and Substantia nigra are his primary areas of study. The study incorporates disciplines such as Glial cell line-derived neurotrophic factor, Neurotrophic factors and Neurodegeneration in addition to Neuroscience. His work in Dopamine covers topics such as Serotonin which are related to areas like Neurotransmitter.

His study looks at the relationship between Parkinson's disease and fields such as Genetic enhancement, as well as how they intersect with chemical problems. His Striatum research is multidisciplinary, relying on both Lesion, Transduction and Oxidopamine. His Substantia nigra research is multidisciplinary, incorporating perspectives in Ventral tegmental area, Axoplasmic transport and Midbrain.

He most often published in these fields:

  • Neuroscience (45.45%)
  • Dopamine (35.35%)
  • Parkinson's disease (31.82%)

What were the highlights of his more recent work (between 2015-2021)?

  • Alpha-synuclein (17.68%)
  • Neurodegeneration (16.16%)
  • Cell biology (14.65%)

In recent papers he was focusing on the following fields of study:

Deniz Kirik focuses on Alpha-synuclein, Neurodegeneration, Cell biology, Phosphorylation and Striatum. His research in Alpha-synuclein intersects with topics in Fibril and Dopaminergic. His study in Neurodegeneration is interdisciplinary in nature, drawing from both Neuroscience, Parkinsonism, In vivo and Green fluorescent protein.

His Neuroscience study frequently draws parallels with other fields, such as Atrophy. Internal medicine, Endocrinology and Dopamine are the two main areas of interest in his Striatum studies. His work carried out in the field of Substantia nigra brings together such families of science as Glial cell line-derived neurotrophic factor, Ventral tegmental area and Midbrain.

Between 2015 and 2021, his most popular works were:

  • How can rAAV-α-synuclein and the fibril α-synuclein models advance our understanding of Parkinson's disease? (54 citations)
  • How is alpha-synuclein cleared from the cell? (38 citations)
  • Gene therapy for Parkinson's disease : Disease modification by GDNF family of ligands (31 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Neuron

Deniz Kirik mainly investigates Alpha-synuclein, Viral vector, Cell biology, Neurotrophic factors and Fibril. His research integrates issues of In vivo and Phosphorylation in his study of Alpha-synuclein. His studies in Viral vector integrate themes in fields like Neurodegeneration and Green fluorescent protein.

His Neurotrophic factors study combines topics in areas such as Endocrinology, Genetic enhancement and Huntingtin. The concepts of his Hyperphosphorylation study are interwoven with issues in Neuroscience and Parkinson's disease. His studies deal with areas such as Dopaminergic and Dopamine as well as Parkinson's disease.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Neuronal replacement from endogenous precursors in the adult brain after stroke

Andreas Arvidsson;Tove Collin;Deniz Kirik;Zaal Kokaia.
Nature Medicine (2002)

3444 Citations

Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

Deniz Kirik;Carl Rosenblad;Corinna Burger;Cecilia Lundberg.
The Journal of Neuroscience (2002)

790 Citations

Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat

Deniz Kirik;Carl Rosenblad;Anders Björklund.
Experimental Neurology (1998)

746 Citations

Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease.

M. Lundblad;M. Andersson;C. Winkler;C. Winkler;D. Kirik.
European Journal of Neuroscience (2002)

739 Citations

Dopamine released from 5-HT terminals is the cause of L-DOPA-induced dyskinesia in parkinsonian rats.

Manolo Carta;Thomas Carlsson;Deniz Kirik;Anders Björklund.
Brain (2007)

668 Citations

Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system.

Deniz Kirik;Carl Rosenblad;Anders Björklund;Ronald J. Mandel.
The Journal of Neuroscience (2000)

610 Citations

Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model.

Anders Björklund;Deniz Kirik;C Rosenblad;B Georgievska.
Brain Research (2000)

485 Citations

L-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of parkinson's disease: relation to motor and cellular parameters of nigrostriatal function.

Christian Winkler;Christian Winkler;Deniz Kirik;Anders Björklund;M.Angela Cenci.
Neurobiology of Disease (2002)

442 Citations

Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: a new primate model of Parkinson's disease.

Deniz Kirik;Lucy E. Annett;Corinna Burger;Nicholas Muzyczka.
Proceedings of the National Academy of Sciences of the United States of America (2003)

440 Citations

Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons

Brian A. Horger;Merry C. Nishimura;Mark P. Armanini;Li-Chong Wang.
The Journal of Neuroscience (1998)

396 Citations

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