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Neuroscience

D-Index
54
Citations
10655
World Ranking
4921
National Ranking
135

Overview

Kay L. Double is affiliated with the University of Sydney in Australia. Their research focuses primarily on Medicine, with a strong emphasis on Neurology, which accounts for the majority of their work. Additional areas of study include Nutrition and Dietetics, Physiology, Cognitive Neuroscience, and Spectroscopy.

Key topics addressed in their publications include:

  • Parkinson's Disease Mechanisms and Treatments
  • Amyotrophic Lateral Sclerosis Research
  • Trace Elements in Health
  • Neurological diseases and metabolism
  • Alzheimer's disease research and treatments
  • Molecular Sensors and Ion Detection
  • Electrochemical Analysis and Applications

The scientist's research outputs have appeared frequently in several publication venues, with multiple papers published in bioRxiv (Cold Spring Harbor Laboratory), Acta Neuropathologica Communications, and PLoS ONE. Other notable venues include Angewandte Chemie International Edition and the Journal of Neural Transmission.

Notable recent papers by Kay L. Double include:

  • "Superoxide Dismutase 1 in Health and Disease: How a Frontline Antioxidant Becomes Neurotoxic," 2020, Angewandte Chemie International Edition
  • "A brief history of brain iron accumulation in Parkinson disease and related disorders," 2022, Journal of Neural Transmission
  • "Co-deposition of SOD1, TDP-43 and p62 proteinopathies in ALS: evidence for multifaceted pathways underlying neurodegeneration," 2022, Acta Neuropathologica Communications
  • "Near-Infrared Ratiometric Fluorescent Probe for Detecting Endogenous Cu2+ in the Brain," 2024, ACS Sensors
  • "Simultaneous structural and elemental nano-imaging of human brain tissue," 2020, Chemical Science

Frequent collaborators include Benjamin G. Trist, Veronica Cottam, Dominic J. Hare, Peter J. Crouch, and Amr H. Abdeen, with the highest number of joint publications attributed to Benjamin G. Trist.

Best Publications

  • Oxidative stress in the aging substantia nigra and the etiology of Parkinson's disease

    Benjamin G. Trist;Dominic J. Hare;Dominic J. Hare;Kay L. Double

  • Brain iron pathways and their relevance to Parkinson's disease.

    D Berg;M. Gerlach;M. B. H. Youdim;K. L. Double

  • Neuromelanin in human dopamine neurons: comparison with peripheral melanins and relevance to Parkinson's disease.

    H Fedorow;F Tribl;G Halliday;M Gerlach

  • Language-associated Cortical Regions Are Proportionally Larger in the Female Brain

    Jenny Harasty;Kay L. Double;Glenda M. Halliday;Jillian J. Kril

  • The relevance of iron in the pathogenesis of Parkinson's disease.

    Mario E. Götz;Kay Double;Manfred Gerlach;Moussa B. H. Youdim

  • Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson's disease.

    Hélène Hall;Stefanie Reyes;Natalie Landeck;Chris Bye

  • Regional Specificity of Brain Atrophy in Huntington's Disease

    G.M. Halliday;D.A. McRitchie;V. Macdonald;K.L. Double

  • Iron and dopamine: a toxic couple

    Dominic J. Hare;Dominic J. Hare;Kay L. Double

  • Topography of brain atrophy during normal aging and alzheimer's disease

    K.L. Double;G.M. Halliday;G.M. Halliday;J.J. Krill;J.J. Krill;J.A. Harasty

  • Copper pathology in vulnerable brain regions in Parkinson's disease.

    Katherine M. Davies;Katherine M. Davies;Sylvain Bohic;Sylvain Bohic;Sylvain Bohic;Asunción Carmona;Asunción Carmona;Richard Ortega;Richard Ortega

  • α-Synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease

    Glenda M. Halliday;Anita Ophof;Melissa Broe;Poul H. Jensen

  • Identifying the pattern of olfactory deficits in Parkinson disease using the brief smell identification test.

    Kay L Double;Dominic B Rowe;Michael Hayes;Daniel K. Y Chan

  • Iron-binding characteristics of neuromelanin of the human substantia nigra.

    Kay L. Double;Manfred Gerlach;Volker Schünemann;Alfred X. Trautwein

  • The comparative biology of neuromelanin and lipofuscin in the human brain

    K L Double;V N Dedov;H Fedorow;E Kettle

  • Dopamine receptor agonists in current clinical use: comparative dopamine receptor binding profiles defined in the human striatum.

    M. Gerlach;K. Double;K. Double;T. Arzberger;F. Leblhuber

  • In Vitro Studies of Ferritin Iron Release and Neurotoxicity

    K. L. Double;M. Maywald;M. Schmittel;P. Riederer

  • Superoxide Dismutase 1 in Health and Disease: How a Frontline Antioxidant Becomes Neurotoxic.

    Benjamin G Trist;James B Hilton;Dominic J Hare;Dominic J Hare;Dominic J Hare;Peter J Crouch

  • Brain iron pathways and their relevance to Parkinson's disease.

    Unknown

  • Localization of copper and copper transporters in the human brain.

    Katherine M. Davies;Dominic J. Hare;Veronica Cottam;Nicholas Chen

  • A53T-Alpha-Synuclein Overexpression Impairs Dopamine Signaling and Striatal Synaptic Plasticity in Old Mice

    Alexander Kurz;Kay L. Double;Isabel Lastres-Becker;Alessandro Tozzi

  • Selective cell death in neurodegeneration: Why are some neurons spared in vulnerable regions?

    K.L. Double;S. Reyes;E.L. Werry;G.M. Halliday

  • Structural Characteristics of Human Substantia Nigra Neuromelanin and Synthetic Dopamine Melanins

    K L Double;L Zecca;P Costi;M Mauer

Frequent Co-Authors

Glenda M. Halliday
Glenda M. Halliday University of Sydney
Moussa B.H. Youdim
Moussa B.H. Youdim Technion – Israel Institute of Technology
Olivier Piguet
Olivier Piguet University of Sydney
Simon J.G. Lewis
Simon J.G. Lewis Macquarie University
Luigi Zecca
Luigi Zecca National Academies of Sciences, Engineering, and Medicine
Caroline Rae
Caroline Rae Neuroscience Research Australia
Daniela Berg
Daniela Berg University Hospital Schleswig-Holstein
Deniz Kirik
Deniz Kirik Lund University
Janet L. Taylor
Janet L. Taylor Edith Cowan University
Georg Auburger
Georg Auburger Goethe University Frankfurt

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