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Neuroscience

D-Index
36
Citations
6869
World Ranking
8942
National Ranking
496

Overview

Manolo Carta is affiliated with the University of Cagliari in Italy and has conducted extensive research primarily in the fields of Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology. Their work extensively covers subfields such as Neurology, Cellular and Molecular Neuroscience, Molecular Biology, Physiology, and Cognitive Neuroscience.

The scientist's research topics focus on:

  • Parkinson's Disease Mechanisms and Treatments
  • Neuroscience and Neuropharmacology Research
  • Neurological disorders and treatments
  • Autism Spectrum Disorder Research
  • Amino Acid Enzymes and Metabolism
  • Neurogenetic and Muscular Disorders Research
  • RNA modifications and cancer

Manolo Carta has collaborated frequently with several researchers, including:

  • Sara Corsi
  • Roberto Stancampiano
  • Roberto Frau
  • Simona Scheggi
  • Silvia Fanni

Research outputs have been published in various scientific venues, with recurring contributions to:

  • Neurobiology of Disease
  • Experimental Neurology
  • Annals of the Rheumatic Diseases
  • European Journal of Neurology
  • Journal of the Neurological Sciences

Some of the notable papers authored include:

  • "Efficacy and safety of 5-hydroxytryptophan on depression and apathy in Parkinson's disease: a preliminary finding" (2020), published in European Journal of Neurology
  • "Homeostasis of serine enantiomers is disrupted in the post-mortem caudate putamen and cerebrospinal fluid of living Parkinson's disease patients" (2023), published in Neurobiology of Disease
  • "Efficacy and safety of 5-Hydroxytryptophan on levodopa-induced motor complications in Parkinson's disease: A preliminary finding" (2020), published in Journal of the Neurological Sciences
  • "Preliminary finding of a randomized, double-blind, placebo-controlled, crossover study to evaluate the safety and efficacy of 5-hydroxytryptophan on REM sleep behavior disorder in Parkinson's disease" (2021), published in Sleep And Breathing
  • "Serotonin/dopamine interaction in the induction and maintenance of L-DOPA-induced dyskinesia: An update" (2021), published in Progress in brain research

Best Publications

  • Dopamine released from 5-HT terminals is the cause of L-DOPA-induced dyskinesia in parkinsonian rats.

    Manolo Carta;Thomas Carlsson;Deniz Kirik;Anders Björklund

  • Transplantation of human embryonic stem cell-derived cells to a rat model of Parkinson's disease: effect of in vitro differentiation on graft survival and teratoma formation.

    Anke Brederlau;Ana Sofia Correia;Sergey V. Anisimov;Muna Elmi

  • Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease.

    Matthieu F. Bastide;Wassilios G. Meissner;Barbara Picconi;Stefania Fasano

  • Critical Involvement of cAMP/DARPP-32 and Extracellular Signal-Regulated Protein Kinase Signaling in l-DOPA-Induced Dyskinesia

    Emanuela Santini;Emmanuel Valjent;Alessandro Usiello;Manolo Carta

  • Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons

    Banafsheh Kadkhodaei;Takehito Ito;Eliza Joodmardi;Bengt Mattsson

  • Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPA-induced dyskinesia.

    Ana Muñoz;Qin Li;Fabrizio Gardoni;Elena Marcello

  • Vitamin A deficiency produces spatial learning and memory impairment in rats.

    S Cocco;Giacomo Diaz;Roberto Stancampiano;Andrea Diana

  • Pharmacological validation of a mouse model of l-DOPA-induced dyskinesia

    M Lundblad;A Usiello;Manolo Carta;K Hakansson

  • Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease.

    Thomas Carlsson;Manolo Carta;Christian Winkler;Anders Björklund

  • Role of striatal L-DOPA in the production of dyskinesia in 6-hydroxydopamine lesioned rats.

    Manolo Carta;Hanna S. Lindgren;Martin Lundblad;Roberto Stancampiano

  • Transcriptome analysis in a rat model of l-DOPA-induced dyskinesia

    Christine Konradi;Jenny E. Westin;Manolo Carta;Molly E. Eaton

  • Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia

    Erwan Bezard;Elisabetta Tronci;Elsa Y. Pioli;Qin Li

  • Serotonin-dopamine interaction in the induction and maintenance of L-DOPA-induced dyskinesias.

    Manolo Carta;Thomas Carlsson;Ana Muñoz;Deniz Kirik

  • Impact of grafted serotonin and dopamine neurons on development of l-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration

    Thomas Carlsson;Manolo Carta;Ana Muñoz;Bengt Mattsson

  • Contribution of pre-synaptic mechanisms to l-DOPA-induced dyskinesia

    Manolo Carta;E Bezard

  • Ventral tegmental area dopamine neurons are resistant to human mutant alpha-synuclein overexpression.

    Matthew Maingay;Marina Romero-Ramos;Manolo Carta;Deniz Kirik

  • Serotonin neuron-dependent and -independent reduction of dyskinesia by 5-HT1A and 5-HT1B receptor agonists in the rat Parkinson model

    Ana Muñoz;Thomas Carlsson;Elisabetta Tronci;Deniz Kirik

  • The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons

    Francesco Errico;Emanuela Santini;Sara Migliarini;Anders Borgkvist

  • Serotonin System Implication in l-DOPA-Induced Dyskinesia: From Animal Models to Clinical Investigations

    Manolo Carta;Elisabetta Tronci

  • Role of serotonin neurons in the induction of levodopa- and graft-induced dyskinesias in Parkinson's disease.

    Manolo Carta;Thomas Carlsson;Ana Muñoz;Deniz Kirik

Frequent Co-Authors

Anders Björklund
Anders Björklund Lund University
Alessandro Usiello
Alessandro Usiello University of Campania "Luigi Vanvitelli"
Deniz Kirik
Deniz Kirik Lund University
Marco Bortolato
Marco Bortolato University of Florida
Gilberto Fisone
Gilberto Fisone Karolinska Institute
Qin Li
Qin Li Peking Union Medical College Hospital
Fabrizio Gardoni
Fabrizio Gardoni University of Milan
Paola Devoto
Paola Devoto University of Cagliari
Roberto Frau
Roberto Frau University of Cagliari
M. Angela Cenci
M. Angela Cenci Lund University

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