D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 82 Citations 17,430 248 World Ranking 11139 National Ranking 437

Overview

What is he best known for?

The fields of study he is best known for:

  • Dopamine
  • Parkinson's disease
  • Neurotransmitter

Jonathan M. Brotchie mostly deals with Parkinson's disease, Neuroscience, Dyskinesia, Levodopa and Dopamine. His Parkinson's disease research incorporates themes from Dopaminergic and Endocrinology. His research integrates issues of Disease, Parkinsonism and Subthalamic nucleus in his study of Neuroscience.

His research in Dyskinesia intersects with topics in Serotonergic and Pharmacology. His biological study spans a wide range of topics, including NMDA receptor, Opioid receptor and Cannabinoid Receptor Agonists. His study in Dopamine is interdisciplinary in nature, drawing from both Degeneration and 5-HT receptor.

His most cited work include:

  • Pathophysiology of levodopa-induced dyskinesia: Potential for new therapies (405 citations)
  • Relationship between the Appearance of Symptoms and the Level of Nigrostriatal Degeneration in a Progressive 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Lesioned Macaque Model of Parkinson's Disease (402 citations)
  • Levodopa-induced dyskinesias. (351 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Parkinson's disease, Dyskinesia, Neuroscience, Pharmacology and Dopamine. His studies deal with areas such as Dopaminergic and Endocrinology as well as Parkinson's disease. Jonathan M. Brotchie has researched Dyskinesia in several fields, including Levodopa, Parkinsonism and MPTP.

Jonathan M. Brotchie studies Neuroscience, focusing on Basal ganglia in particular. His Pharmacology study combines topics from a wide range of disciplines, such as Receptor, Antagonist and Dihydroxyphenylalanine. His Dopamine research incorporates themes from NMDA receptor and Opioid peptide.

He most often published in these fields:

  • Parkinson's disease (46.85%)
  • Dyskinesia (41.34%)
  • Neuroscience (35.83%)

What were the highlights of his more recent work (between 2014-2021)?

  • Parkinson's disease (46.85%)
  • Pharmacology (35.43%)
  • Neuroscience (35.83%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Parkinson's disease, Pharmacology, Neuroscience, Dyskinesia and Dopaminergic. The Parkinson's disease study combines topics in areas such as Dopamine and Parkinsonism. His Pharmacology research integrates issues from Peripheral blood mononuclear cell, Potency, Kinase and LRRK2.

His Neuroscience research is multidisciplinary, relying on both Pathophysiology and Disease. The various areas that Jonathan M. Brotchie examines in his Dyskinesia study include Levodopa, Cognition and MPTP. Endocrinology and Internal medicine are the main topics of his Dopaminergic study.

Between 2014 and 2021, his most popular works were:

  • Animal models of [alpha]-synucleinopathy for Parkinson disease drug development (85 citations)
  • α-Synuclein-Based Animal Models of Parkinson's Disease: Challenges and Opportunities in a New Era (71 citations)
  • Management of impulse control disorders in Parkinson's disease: Controversies and future approaches (66 citations)

In his most recent research, the most cited papers focused on:

  • Dopamine
  • Neurotransmitter
  • Internal medicine

Jonathan M. Brotchie spends much of his time researching Parkinson's disease, Dopaminergic, Neuroscience, Dopamine and Pharmacology. His Parkinson's disease study frequently links to other fields, such as Neurodegeneration. His Neuroscience study frequently links to related topics such as Disease.

In his work, Anatomy and Nigrostriatal pathway is strongly intertwined with Macaque, which is a subfield of Dopamine. His Pharmacology research incorporates elements of Neurotoxicity, Trehalose, Dyskinesia, Neurochemical and Reuptake inhibitor. His research investigates the connection with Dyskinesia and areas like MPTP which intersect with concerns in Receptor antagonist.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Relationship between the Appearance of Symptoms and the Level of Nigrostriatal Degeneration in a Progressive 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Lesioned Macaque Model of Parkinson's Disease

Erwan Bezard;Erwan Bezard;Sandra Dovero;Caroline Prunier;Paula Ravenscroft.
The Journal of Neuroscience (2001)

642 Citations

Pathophysiology of levodopa-induced dyskinesia: Potential for new therapies

Erwan Bezard;Jonathan M. Brotchie;Christian E. Gross.
Nature Reviews Neuroscience (2001)

619 Citations

Levodopa-induced dyskinesias.

Giovanni Fabbrini;Jonathan M. Brotchie;Francisco Grandas;Masahiro Nomoto.
Movement Disorders (2007)

554 Citations

Presymptomatic compensation in Parkinson's disease is not dopamine-mediated

Erwan Bezard;Christian E. Gross;Jonathan M. Brotchie.
Trends in Neurosciences (2003)

388 Citations

Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's disease.

Vincenzo Di Marzo;Michael P. Hill;Tiziana Bisogno;Alan R. Crossman.
The FASEB Journal (2000)

372 Citations

Novel pharmacological targets for the treatment of Parkinson's disease

Anthony H V Schapira;Erwan Bezard;Jonathan Brotchie;Frédéric Calon.
Nature Reviews Drug Discovery (2006)

372 Citations

Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease: a pilot study.

K.A. Sieradzan;S.H. Fox;M. Hill;J.P.R. Dick.
Neurology (2001)

371 Citations

The Pharmacology of l-DOPA-Induced Dyskinesia in Parkinson’s Disease

Philippe Huot;Tom H. Johnston;James B. Koprich;Susan H. Fox.
Pharmacological Reviews (2013)

301 Citations

Alleviation of parkinsonism by antagonism of excitatory amino acid transmission in the medial segment of the globus pallidus in rat and primate.

Jonathan M. Brotchie;Ian J. Mitchell;Michael A. Sambrook;Alan R. Crossman.
Movement Disorders (1991)

284 Citations

Characterization of enhanced behavioral responses to L-DOPA following repeated administration in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease.

Brian Henry;Alan R. Crossman;Jonathan M. Brotchie.
Experimental Neurology (1998)

272 Citations

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