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Thérèse Di Paolo

Thérèse Di Paolo

D-Index & Metrics

Medicine

D-Index
73
Citations
14656
World Ranking
19730
National Ranking
836

Overview

Thérèse Di Paolo is affiliated with Université Laval in Canada, focusing primarily on neuroscience and medicine. Their research extensively explores the mechanisms and treatments of Parkinson's disease, delving into neuroinflammation, neurodegeneration, and the neuroimmune system's role in neurological disorders.

The scientist's work spans multiple fields, most notably:

  • Neuroscience
  • Medicine

Within these broad categories, Di Paolo has contributed to several key subfields including:

  • Neurology
  • Cellular and Molecular Neuroscience
  • Molecular Biology
  • Physiology
  • Endocrinology, Diabetes and Metabolism

The core topics addressed in Di Paolo's research cover:

  • Parkinson's Disease Mechanisms and Treatments
  • Nuclear Receptors and Signaling
  • Neuroscience and Neuropharmacology Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Nerve injury and regeneration
  • Neurological disorders and treatments
  • Long-Term Effects of COVID-19

Di Paolo's publication record includes several recent papers that illustrate the scope and focus of their research. These include:

  • "Microglial Implications in SARS-CoV-2 Infection and COVID-19: Lessons From Viral RNA Neurotropism and Possible Relevance to Parkinson's Disease," 2021, Frontiers in Cellular Neuroscience
  • "Levodopa partially rescues microglial numerical, morphological, and phagolysosomal alterations in a monkey model of Parkinson's disease," 2020, Brain Behavior and Immunity
  • "Neuroactive steroids and Parkinson's disease: Review of human and animal studies," 2023, Neuroscience & Biobehavioral Reviews
  • "Impact of sex on neuroimmune contributions to Parkinson's disease," 2023, Brain Research Bulletin
  • "Remodeling microglia to a protective phenotype in Parkinson's disease?," 2020, Neuroscience Letters

Their research is frequently published in several specialized venues, including:

  • Brain Research Bulletin
  • Cells
  • Frontiers in Cellular Neuroscience
  • Neuroscience & Biobehavioral Reviews
  • Brain Behavior and Immunity

Collaboration plays a significant role in Di Paolo's work. Frequent co-authors include:

  • Mélanie Bourque
  • Marc Morissette
  • Denis Soulet
  • Marie-Ève Tremblay
  • Jérôme Lamontagne-Proulx

Best Publications

  • Neuroprotective actions of sex steroids in Parkinson's disease.

    Mélanie Bourque;Dean E. Dluzen;Thérèse Di Paolo

  • Increased adenosine A2A receptors in the brain of Parkinson’s disease patients with dyskinesias

    Frédéric Calon;Mehdi Dridi;Oleh Hornykiewicz;Paul J Bédard

  • Levodopa-induced motor complications are associated with alterations of glutamate receptors in Parkinson's disease.

    Frédéric Calon;Ali H Rajput;Oleh Hornykiewicz;Oleh Hornykiewicz;Paul J Bédard

  • 17β-estradiol at a physiological dose acutely increases dopamine turnover in rat brain

    Thérése Di Paolo;Claude Rouillard;Paul Bédard

  • Control of ACTH secretion by the central nucleus of the amygdala: implication of the serotoninergic system and its relevance to the glucocorticoid delayed negative feedback mechanism.

    Serge Beaulieu;Thérèse Di Paolo;Nicholas Barden

  • Estrogenic modulation of brain activity: implications for schizophrenia and Parkinson's disease.

    Michel Cyr;Frederic Calon;Marc Morissette;Thérèse Di Paolo

  • Neuroprotective properties of 17beta-estradiol, progesterone, and raloxifene in MPTP C57Bl/6 mice.

    Sophie Callier;Sophie Callier;Marc Morissette;Michelle Grandbois;Didier Pélaprat

  • Ovarian steroids and selective estrogen receptor modulators activity on rat brain NMDA and AMPA receptors.

    Michel Cyr;Othman Ghribi;Caroline Thibault;Marc Morissette

  • Defective dentate nucleus GABA receptors in essential tremor

    Sarah Paris-Robidas;Elodie Brochu;Marion Sintes;Vincent Emond

  • AFQ056 treatment of levodopa-induced dyskinesias: Results of 2 randomized controlled trials

    Daniela Berg;Jana Godau;Claudia Trenkwalder;Karla Eggert

  • Rapid conversion of high into low striatal D2-dopamine receptor agonist binding states after an acute physiological dose of 17β-estradiol

    Daniel Lévesque;Thérèse Di Paolo

  • Brain dopamine transporter: Gender differences and effect of chronic haloperidol

    Robert Rivest;Pierre Falardeau;Thérèse Di Paolo

  • Increase of preproenkephalin mRNA levels in the putamen of Parkinson disease patients with levodopa-induced dyskinesias.

    Frédéric Calon;Sam Birdi;Ali H. Rajput;Oleh Hornykiewicz

  • Effect of chronic estradiol and haloperidol treatment on striatal dopamine receptors.

    Thérèse Di Paolo;Patrick Poyet;Fernand Labrie

  • Steroids-dopamine interactions in the pathophysiology and treatment of CNS disorders.

    Maria Gabriela Sánchez;Mélanie Bourque;Marc Morissette;Thérèse Di Paolo

  • mGluR5 metabotropic glutamate receptors and dyskinesias in MPTP monkeys

    Pershia Samadi;Laurent Grégoire;Marc Morissette;Fréderic Calon

  • Role of adenosine A2A receptors in parkinsonian motor impairment and l-DOPA-induced motor complications.

    Micaela Morelli;Therese Di Paolo;Jadwiga Wardas;Frederic Calon

  • Preproenkephalin mRNA expression in the caudate-putamen of MPTP monkeys after chronic treatment with the D2 agonist U91356A in continuous or intermittent mode of administration: comparison with L-DOPA therapy.

    Marc Morissette;Martin Goulet;Jean-Jacques Soghomonian;Pierre J Blanchet

  • Estrogen and SERM neuroprotection in animal models of Parkinson's disease

    Marc Morissette;Sara Al Sweidi;Sophie Callier;Thérèse Di Paolo

  • Stereospecific prevention by 17beta-estradiol of MPTP-induced dopamine depletion in mice.

    Sophie Callier;Sophie Callier;Marc Morissette;Michelle Grbois;Thérèse Di Paolo

Frequent Co-Authors

Marc Morissette
Marc Morissette Université Laval
Paul J. Bédard
Paul J. Bédard Université Laval
Laurent Grégoire
Laurent Grégoire Université Laval
Frédéric Calon
Frédéric Calon Université Laval
Dean E. Dluzen
Dean E. Dluzen John A. Logan College
Claude Rouillard
Claude Rouillard Université Laval
Martin Parent
Martin Parent Université Laval
Fernand Labrie
Fernand Labrie Université Laval
Richard Grondin
Richard Grondin University of Kentucky
Marie-Ève Tremblay
Marie-Ève Tremblay University of Victoria

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