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Frédéric Calon

Frédéric Calon

D-Index & Metrics

Neuroscience

D-Index
76
Citations
17687
World Ranking
1953
National Ranking
112

Overview

Frédéric Calon is affiliated with Université Laval in Canada. Their research focuses on multiple areas within medicine and neuroscience, with significant contributions in physiology, neurology, cancer research, cellular and molecular neuroscience, and cardiology and cardiovascular medicine.

Their primary research topics include:

  • Alzheimer's disease research and treatments
  • Cancer, lipids, and metabolism
  • Lipid metabolism and disorders
  • Neuroinflammation and neurodegeneration mechanisms
  • Diet and metabolism studies
  • Neuroscience and neuropharmacology research
  • Fatty acid research and health

Key recent papers authored or coauthored by Frédéric Calon include:

  • "Tetrahydrobioterin (BH4) Pathway: From Metabolism to Neuropsychiatry" (2020), published in Current Neuropharmacology
  • "Cerebrovascular insulin receptors are defective in Alzheimer's disease" (2022), published in Brain
  • "State of the Science on Brain Insulin Resistance and Cognitive Decline Due to Alzheimer's Disease" (2023), published in Aging and Disease
  • "Neuroligin-1 is altered in the hippocampus of Alzheimer's disease patients and mouse models, and modulates the toxicity of amyloid-beta oligomers" (2020), published in Scientific Reports
  • "Higher angiotensin-converting enzyme 2 (ACE2) levels in the brain of individuals with Alzheimer's disease" (2023), published in Acta Neuropathologica Communications

Frequent coauthors collaborating with Calon include Cyntia Tremblay, Manon Leclerc, Nabil G. Seidah, Vincent Émond, and David A. Bennett.

The major journals and publication venues frequently featuring Calon's work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alzheimer's & Dementia
  • Research Square (Research Square)
  • Journal of Clinical Oncology
  • Scientific Reports

Best Publications

  • A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model.

    Giselle P. Lim;Frédéric Calon;Takashi Morihara;Fusheng Yang

  • Docosahexaenoic Acid Protects from Dendritic Pathology in an Alzheimer's Disease Mouse Model

    Frédéric Calon;Giselle P. Lim;Giselle P. Lim;Fusheng Yang;Fusheng Yang;Takashi Morihara;Takashi Morihara

  • Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease.

    Carl Julien;Cyntia Tremblay;Vincent Émond;Meryem Lebbadi

  • Novel pharmacological targets for the treatment of Parkinson's disease

    Anthony H V Schapira;Erwan Bezard;Jonathan Brotchie;Frédéric Calon

  • Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease.

    Lixia Zhao;Qiu-Lan Ma;Qiu-Lan Ma;Frédéric Calon;Marni E Harris-White;Marni E Harris-White

  • Neuroprotective action of omega-3 polyunsaturated fatty acids against neurodegenerative diseases: evidence from animal studies.

    Frédéric Calon;Greg Cole;Greg Cole

  • High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model.

    Carl Julien;Cyntia Tremblay;Alix Phivilay;Line Berthiaume

  • Aberrant Lipid Metabolism in the Forebrain Niche Suppresses Adult Neural Stem Cell Proliferation in an Animal Model of Alzheimer’s Disease

    Laura K. Hamilton;Martin Dufresne;Sandra E. Joppé;Sarah Petryszyn

  • Cerebrovascular and blood-brain barrier impairments in Huntington's disease : Potential implications for its pathophysiology

    Janelle Drouin-Ouellet;Stephen J Sawiak;Giulia Cisbani;Marie Lagacé

  • Docosahexaenoic acid-derived neuroprotectin D1 induces neuronal survival via secretase- and PPARγ-mediated mechanisms in Alzheimer's disease models.

    Yuhai Zhao;Frederic Calon;Carl Julien;Jeremy W. Winkler

  • Beneficial effects of dietary omega-3 polyunsaturated fatty acid on toxin-induced neuronal degeneration in an animal model of Parkinson’s disease

    M. Bousquet;M. Saint-Pierre;C. Julien;N. Salem

  • Dietary n-3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's disease.

    Frédéric Calon;Giselle P. Lim;Giselle P. Lim;Takashi Morihara;Takashi Morihara;Fusheng Yang;Fusheng Yang

  • Intravenous nonviral gene therapy causes normalization of striatal tyrosine hydroxylase and reversal of motor impairment in experimental parkinsonism.

    Yun Zhang;Frederic Calon;Chunni Zhu;Ruben J. Boado

  • Increased adenosine A2A receptors in the brain of Parkinson’s disease patients with dyskinesias

    Frédéric Calon;Mehdi Dridi;Oleh Hornykiewicz;Paul J Bédard

  • Diffusion of docosahexaenoic and eicosapentaenoic acids through the blood-brain barrier: An in situ cerebral perfusion study.

    Melissa Ouellet;Vincent Emond;Chuck T. Chen;Carl Julien

  • Insulin Reverses the High-Fat Diet–Induced Increase in Brain Aβ and Improves Memory in an Animal Model of Alzheimer Disease

    Milene Vandal;Phillip J. White;Cyntia Tremblay;Isabelle St-Amour;Isabelle St-Amour

  • Levodopa-induced motor complications are associated with alterations of glutamate receptors in Parkinson's disease.

    Frédéric Calon;Ali H Rajput;Oleh Hornykiewicz;Oleh Hornykiewicz;Paul J Bédard

  • miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo

    Pascal Y. Smith;Julia Hernandez-Rapp;Francis Jolivette;Cynthia Lecours

  • Estrogenic modulation of brain activity: implications for schizophrenia and Parkinson's disease.

    Michel Cyr;Frederic Calon;Marc Morissette;Thérèse Di Paolo

  • DHA improves cognition and prevents dysfunction of entorhinal cortex neurons in 3xTg-AD mice.

    Dany Arsenault;Carl Julien;Cyntia Tremblay;Frédéric Calon

Frequent Co-Authors

Paul J. Bédard
Paul J. Bédard Université Laval
Marc Morissette
Marc Morissette Université Laval
Francesca Cicchetti
Francesca Cicchetti Université Laval
Emmanuel Planel
Emmanuel Planel Université Laval
Greg M. Cole
Greg M. Cole University of California, Los Angeles
Sophie Layé
Sophie Layé University of Bordeaux
David A. Bennett
David A. Bennett Rush University Medical Center
Richard Grondin
Richard Grondin University of Kentucky
Julie A. Schneider
Julie A. Schneider Rush University Medical Center
Yves Desjardins
Yves Desjardins Université Laval

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