World's Best Scientists 2026 revealed!
Francesca Cicchetti

Francesca Cicchetti

D-Index & Metrics

Neuroscience

D-Index
57
Citations
9226
World Ranking
4416
National Ranking
253

Overview

Francesca Cicchetti is affiliated with Université Laval in Canada and conducts research primarily in neuroscience, medicine, and biochemistry, genetics, and molecular biology. Their work spans various subfields including molecular biology, cellular and molecular neuroscience, neurology, physiology, and developmental neuroscience.

The scientist's research topics cover:

  • Genetic Neurodegenerative Diseases
  • Mitochondrial Function and Pathology
  • Neurological disorders and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Parkinson's Disease Mechanisms and Treatments
  • Muscle Physiology and Disorders
  • Neuroscience and Neuropharmacology Research

Francesca Cicchetti has published extensively in several scientific journals. Frequent publication venues include:

  • Neurobiology of Disease
  • Molecular Psychiatry
  • Journal of Neurology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Therapy

Selected recent papers demonstrate their focus on neurodegenerative mechanisms, neuroinflammation, and neurological disease models:

  • Neuronal interleukin-1 receptors mediate pain in chronic inflammatory diseases, 2020, The Journal of Experimental Medicine
  • Microglial physiological properties and interactions with synapses are altered at presymptomatic stages in a mouse model of Huntington's disease pathology, 2020, Journal of Neuroinflammation
  • Sox6 expression distinguishes dorsally and ventrally biased dopamine neurons in the substantia nigra with distinctive properties and embryonic origins, 2021, Cell Reports
  • The contribution of inflammatory astrocytes to BBB impairments in a brain-chip model of Parkinson's disease, 2023, Nature Communications
  • A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease, 2022, PLoS Biology

The scientist collaborates frequently with several coauthors, including Melanie Alpaugh, Hélèna L. Denis, Martine Saint-Pierre, Aurélie de Rus Jacquet, and Abid Oueslati. These collaborations span a range of topics within neurological and molecular studies.

Best Publications

  • Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?

    Francesca Cicchetti;Janelle Drouin-Ouellet;Robert E. Gross

  • Defining Midbrain Dopaminergic Neuron Diversity by Single-Cell Gene Expression Profiling

    Jean Francois Poulin;Jian Zou;Janelle Drouin-Ouellet;Kwang Youn A. Kim

  • Transplanted fetal striatum in Huntington's disease: Phenotypic development and lack of pathology

    Thomas B. Freeman;Francesca Cicchetti;Robert A. Hauser;Terrence W. Deacon

  • Cerebrovascular and blood-brain barrier impairments in Huntington's disease : Potential implications for its pathophysiology

    Janelle Drouin-Ouellet;Stephen J Sawiak;Giulia Cisbani;Marie Lagacé

  • Beneficial effects of dietary omega-3 polyunsaturated fatty acid on toxin-induced neuronal degeneration in an animal model of Parkinson’s disease

    M. Bousquet;M. Saint-Pierre;C. Julien;N. Salem

  • Chemical anatomy of striatal interneurons in normal individuals and in patients with Huntington’s disease

    Francesca Cicchetti;Lucı́a Prensa;Ying Wu;André Parent

  • Rotenone induces non-specific central nervous system and systemic toxicity

    Nicolas Lapointe;Michel St-Hilaire;Maria-Grazia Martinoli;Julie Blanchet

  • Systemic exposure to paraquat and maneb models early Parkinson's disease in young adult rats.

    Francesca Cicchetti;Nicolas Lapointe;Antoine Roberge-Tremblay;Martine Saint-Pierre

  • Cellular and molecular mechanisms of action of transcranial direct current stimulation: evidence from in vitro and in vivo models.

    Simon J. Pelletier;Francesca Cicchetti

  • Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration

    F. Cicchetti;S. Saporta;R. A. Hauser;M. Parent

  • The current model of basal ganglia organization under scrutiny

    Unknown

  • Mutant huntingtin is present in neuronal grafts in Huntington disease patients.

    Francesca Cicchetti;Steve Lacroix;Giulia Cisbani;Nicolas Vallières

  • Human-to-mouse prion-like propagation of mutant huntingtin protein

    Iksoo Jeon;Francesca Cicchetti;Giulia Cisbani;Suji Lee

  • Differences between subacute and chronic MPTP mice models: investigation of dopaminergic neuronal degeneration and α‐synuclein inclusions

    Claire Gibrat;Martine Saint-Pierre;Mélanie Bousquet;Daniel Lévesque

  • Modulation of brain-derived neurotrophic factor as a potential neuroprotective mechanism of action of omega-3 fatty acids in a parkinsonian animal model

    M. Bousquet;C. Gibrat;M. Saint-Pierre;C. Julien

  • Toll-Like Receptor Expression in the Blood and Brain of Patients and a Mouse Model of Parkinson’s Disease

    Janelle Drouin-Ouellet;Isabelle St-Amour;Martine Saint-Pierre;Jérôme Lamontagne-Proulx

  • The role of tau in the pathological process and clinical expression of Huntington's disease.

    Romina Vuono;Sophie Winder-Rhodes;Sophie Winder-Rhodes;Rohan de Silva;Giulia Cisbani

  • Impact of omega-3 fatty acids in Parkinson's disease

    Mélanie Bousquet;Frédéric Calon;Francesca Cicchetti

  • microRNA-132/212 deficiency enhances Aβ production and senile plaque deposition in Alzheimer's disease triple transgenic mice.

    Julia Hernandez-Rapp;Sara Rainone;Claudia Goupil;Véronique Dorval

  • The different effects of LPS and poly I:C prenatal immune challenges on the behavior, development and inflammatory responses in pregnant mice and their offspring.

    Dany Arsenault;Isabelle St-Amour;Giulia Cisbani;Louis-Simon Rousseau

  • Neuronal degeneration in the basal ganglia and loss of pallido-subthalamic synapses in mice with targeted disruption of the Huntington's disease gene

    John R O'Kusky;Jamal Nasir;Francesca Cicchetti;Andre Parent

  • Cerebral PET imaging and histological evidence of transglutaminase inhibitor cystamine induced neuroprotection in transgenic R6/2 mouse model of Huntington's disease

    Xukui Wang;Aparajita Sarkar;Francesca Cicchetti;Meixiang Max Yu

Frequent Co-Authors

Roger A. Barker
Roger A. Barker University of Cambridge
Frédéric Calon
Frédéric Calon Université Laval
André Parent
André Parent Université Laval
Claude Rouillard
Claude Rouillard Université Laval
Marie-Ève Tremblay
Marie-Ève Tremblay University of Victoria
Emmanuel Planel
Emmanuel Planel Université Laval
Anna-Liisa Brownell
Anna-Liisa Brownell Harvard University
Martin Parent
Martin Parent Université Laval
Jeffrey H. Kordower
Jeffrey H. Kordower Arizona State University
Diego Mantovani
Diego Mantovani Université Laval

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a career in neuroscience can begin with an array of online degree options tailored to fit different goals and lifestyles. For those eager to enter the workforce swiftly, accelerated programs allow students to complete their studies faster while maintaining rigorous academic standards.

It’s important to consider your long-term professional prospects when choosing a major. If you’re wondering what bachelors degree should I get, many neuroscience-related fields align with some of the most sought-after specializations in science, healthcare, and technology.

In addition, degrees that fall under most profitable degrees often include programs in biological sciences, cognitive science, and related disciplines—making neuroscience a strong candidate for both passion and profitability.

Cost is another key factor. You can pursue your studies without breaking the bank by attending fafsa approved online colleges. These institutions typically offer greater access to financial aid, making an online neuroscience degree more affordable and accessible.

Best Scientists Citing Francesca Cicchetti

Trending Scientists