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Michael W. McBurney

Michael W. McBurney

D-Index & Metrics

Molecular Biology

D-Index
80
Citations
28843
World Ranking
988
National Ranking
31

Overview

Michael W. McBurney is affiliated with the University of Ottawa in Canada. Their research encompasses several areas within medicine and biological sciences, with a particular focus on molecular and cellular mechanisms related to aging, metabolism, and protease regulation.

The scientist has contributed to fields including:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, McBurney's work also addresses specific subfields such as:

  • Geriatrics and Gerontology
  • Cell Biology
  • Physiology

Their research topics show a concentration on biochemical processes and metabolic regulation, including:

  • Sirtuins and Resveratrol in Medicine
  • Calpain Protease Function and Regulation
  • Adipose Tissue and Metabolism

One recent publication by McBurney is titled "Resveratrol Inhibits Neointimal Growth after Arterial Injury in High-Fat-Fed Rodents: The Roles of SIRT1 and AMPK", published in 2020 in the Journal of Vascular Research. This paper investigates the molecular pathways involving SIRT1 and AMPK in the context of vascular injury and the effects of resveratrol, a compound frequently studied for its role in aging and metabolism.

The scientist has ongoing collaborations with multiple co-authors, reflecting a multi-disciplinary approach to their research. Frequent collaborators include:

  • June Guo
  • Troy J. Pereira
  • Yusaku Mori
  • Marel Gonzalez Medina
  • Danna M. Breen

Publications by McBurney are largely found in the Journal of Vascular Research, indicating a consistent engagement with vascular biology and related biomedical research areas.

Best Publications

  • Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma.

    Frédéric Picard;Martin Kurtev;Namjin Chung;Acharawan Topark-Ngarm

  • Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation of subependymal cells

    Cindi M. Morshead;Brent A. Reynolds;Constance G. Craig;Michael W. McBurney

  • Mammalian SIRT1 Represses Forkhead Transcription Factors

    Maria Carla Motta;Nullin Divecha;Madeleine Lemieux;Christopher Kamel

  • Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells.

    E M Jones-Villeneuve;M W McBurney;K A Rogers;V I Kalnins

  • Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells.

    Laura Bordone;Maria Carla Motta;Frédéric Picard;Ashley Robinson

  • Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt

    Marcella Fulco;Yana Cen;Po Zhao;Eric P. Hoffman

  • AMP-Activated Protein Kinase–Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

    Jee Hyun Um;Sung-Jun Park;Hyeog Kang;Shutong Yang

  • Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade

    Joy Hsu;Jonathan J. Hodgins;Malvika Marathe;Chris J. Nicolai

  • The Mammalian SIR2α Protein Has a Role in Embryogenesis and Gametogenesis

    Michael W. McBurney;Xiaofeng Yang;Karen Jardine;Mary Hixon

  • Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line

    M. W. McBurney;E. M. V. Jones-Villeneuve;M. K. S. Edwards;P. J. Anderson

  • Identification of XAF1 as an antagonist of XIAP anti-Caspase activity.

    Peter Liston;Wai Gin Fong;N. Lynn Kelly;Shingo Toji

  • SIRT1 is essential for normal cognitive function and synaptic plasticity

    Shaday Michán;Ying Li;Maggie Meng Hsiu Chou;Edoardo Parrella

  • Isolation of male embryonal carcinoma cells and their chromosome replication patterns

    Michael W. McBurney;Brenda J. Rogers

  • P19 embryonal carcinoma cells.

    M W McBurney

  • Fate of teratocarcinoma cells injected into early mouse embryos

    Papaioannou Ve;McBurney Mw;Gardner Rl;Evans Mj

  • SirT1 regulates energy metabolism and response to caloric restriction in mice.

    Gino Boily;Erin L. Seifert;Lisa Bevilacqua;Xiao Hong He

  • Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter.

    Chaker N. Adra;Poppo H. Boer;Michael W. McBurney

  • Retinoic acid-induced neural differentiation of embryonal carcinoma cells.

    E. M. V. Jones-Villeneuve;M. A. Rudnicki;J. F. Harris;M. W. Mcburney

  • SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons.

    Ying Li;Wei Xu;Michael W. McBurney;Valter D. Longo

  • SIRT1 Negatively Regulates the Mammalian Target of Rapamycin

    Hiyaa Singhee Ghosh;Michael McBurney;Paul D. Robbins

Frequent Co-Authors

John C. Bell
John C. Bell University of Ottawa
Michael A. Rudnicki
Michael A. Rudnicki Ottawa Hospital Research Institute
Wei Gu
Wei Gu Columbia University
Irfan Rahman
Irfan Rahman University of Rochester
Richard G. Pestell
Richard G. Pestell The Wistar Institute
Hongwei Yao
Hongwei Yao Brown University
René St-Arnaud
René St-Arnaud Shriners Hospitals for Children - Erie
Kim Boekelheide
Kim Boekelheide Brown University
Ruth S. Slack
Ruth S. Slack University of Ottawa

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