World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
90
Citations
36520
World Ranking
1063
National Ranking
19

Medicine

D-Index
91
Citations
36983
World Ranking
11611
National Ranking
470

Overview

John C. Bell is affiliated with the University of Ottawa in Canada. Their research focuses on several fields within biology and medicine, prominently including biochemistry, genetics and molecular biology, and medicine. The scientist's work spans multiple subfields such as genetics, molecular biology, oncology, infectious diseases, and immunology.

Key topics covered in their research include:

  • Virus-based gene therapy research
  • CAR-T cell therapy research
  • SARS-CoV-2 and COVID-19 research
  • Cancer research and treatments
  • Animal virus infections studies
  • Immunotherapy and immune responses
  • Viral infectious diseases and gene expression in insects

John C. Bell has contributed to a number of recent scholarly articles. These include:

  • Viral Delivery of CAR Targets to Solid Tumors Enables Effective Cell Therapy, 2020, Molecular Therapy - Oncolytics
  • Extracellular Vesicles and Viruses: Two Intertwined Entities, 2023, International Journal of Molecular Sciences
  • Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination, 2021, Nature Communications
  • Engineering and combining oncolytic measles virus for cancer therapy, 2020, Cytokine & Growth Factor Reviews
  • Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy, 2022, Nature Communications

The scientist works collaboratively with several frequent co-authors, including Carolina S. Ilkow, Taha Azad, Mathieu J. F. Crupi, Stephen Boulton, and Ragunath Singaravelu.

Their publications appear regularly in several scientific venues. Frequent publication outlets comprise:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Molecular Therapy
  • Nature Communications
  • Cancer Immunology Research

Best Publications

  • An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress

    Heather P. Harding;Yuhong Zhang;Huiquing Zeng;Isabel Novoa

  • Regulation of cell adhesion and anchorage-dependent growth by a new β1-integrin-linked protein kinase

    Gregory E. Hannigan;Chungyee Leung-Hagesteijn;Linda Fitz-Gibbon;Marc G. Coppolino;Marc G. Coppolino

  • Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus.

    David F. Stojdl;Brian Lichty;Shane Knowles;Ricardo Marius

  • VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents

    David F Stojdl;Brian D Lichty;Benjamin R tenOever;Jennifer M Paterson

  • ER stress‐regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

    Meixia Bi;Christine Naczki;Marianne Koritzinsky;Diane Fels

  • Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer

    Jeong Heo;Tony Reid;Leyo Ruo;Caroline J. Breitbach

  • ONCOLYTIC VIROTHERAPY

    Unknown

  • Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade

    Joy Hsu;Jonathan J. Hodgins;Malvika Marathe;Chris J. Nicolai

  • The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution.

    Karen Colwill;Tony Pawson;Brenda Andrews;Jayendra Prasad

  • Recent progress in the battle between oncolytic viruses and tumours.

    Kelley A. Parato;Donna Senger;Peter A. J. Forsyth;John C. Bell

  • Going viral with cancer immunotherapy

    Brian D. Lichty;Caroline J. Breitbach;David F. Stojdl;John C. Bell

  • Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans

    Caroline J. Breitbach;James Burke;Derek Jonker;Derek Jonker;Joe Stephenson

  • Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial

    Byeong Ho Park;Taeho Hwang;Taeho Hwang;Ta Chiang Liu;Daniel Y. Sze

  • Activating transcription factor 4 is translationally regulated by hypoxic stress.

    Jaime D. Blais;Vasilisa Filipenko;Meixia Bi;Heather P. Harding

  • Vesicular stomatitis virus: re-inventing the bullet

    Brian D Lichty;Anthony T Power;David F Stojdl;John C Bell

  • Oncolytic viruses as engineering platforms for combination immunotherapy.

    Kwame Twumasi-Boateng;Jessica L Pettigrew;Y Y Eunice Kwok;John C Bell;John C Bell

  • Targeted Inflammation During Oncolytic Virus Therapy Severely Compromises Tumor Blood Flow

    Caroline J Breitbach;Jennifer M Paterson;Chantal G Lemay;Theresa J Falls

  • Translational control of the innate immune response through IRF-7

    Rodney Colina;Mauro Costa-Mattioli;Ryan J. O. Dowling;Maritza Jaramillo

  • Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress

    Jaime D. Blais;Christina L. Addison;Robert Edge;Theresa Falls

  • Cloning and characterization of a second member of the mouse mdr gene family.

    P Gros;M Raymond;J Bell;D Housman

  • Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR.

    Ninan Abraham;David F. Stojdl;Peter I. Duncan;Nathalie Méthot

Frequent Co-Authors

Brian D. Lichty
Brian D. Lichty McMaster University
David Kirn
David Kirn University of California, Berkeley
John Hiscott
John Hiscott Istituto Pasteur
Nahum Sonenberg
Nahum Sonenberg McGill University
Barbara C. Vanderhyden
Barbara C. Vanderhyden University of Ottawa
Brad H. Nelson
Brad H. Nelson University of British Columbia
Grant McFadden
Grant McFadden Arizona State University
Michael W. McBurney
Michael W. McBurney University of Ottawa
Alan Melcher
Alan Melcher Institute of Cancer Research
Christof von Kalle
Christof von Kalle Charité - University Medicine Berlin

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