2004 - Fellow of the Royal Society of Canada Academy of Science
His primary areas of study are Virology, Myxoma virus, Virus, Immune system and Molecular biology. The Virology study combines topics in areas such as Innate immune system, Virulence and Cell biology. His work carried out in the field of Myxoma virus brings together such families of science as Tumor necrosis factor alpha, Apoptosis, Interferon, Glycoprotein and Ankyrin repeat.
The concepts of his Virus study are interwoven with issues in Leporipoxvirus, Poxviridae and Gene. His research integrates issues of Host, Secretory protein and Antibody in his study of Immune system. His Molecular biology research integrates issues from CCL21, Chemokine receptor, CCR1, Serpin and Receptor.
Grant McFadden focuses on Myxoma virus, Virology, Virus, Oncolytic virus and Molecular biology. While the research belongs to areas of Myxoma virus, Grant McFadden spends his time largely on the problem of Tumor necrosis factor alpha, intersecting his research to questions surrounding Receptor and Cytokine. The study incorporates disciplines such as Gene, Virulence, Poxviridae and Immune system in addition to Virology.
He works mostly in the field of Virus, limiting it down to concerns involving Cell biology and, occasionally, Apoptosis. His studies in Oncolytic virus integrate themes in fields like Cancer cell and Glioma. His Molecular biology research includes elements of Plasmid, DNA, Inverted repeat, Mutant and Peptide sequence.
His scientific interests lie mostly in Myxoma virus, Oncolytic virus, Virology, Virus and Cancer research. His research in Myxoma virus intersects with topics in Ex vivo, Leporipoxvirus, Cell biology, Myxomatosis and Programmed cell death. Grant McFadden interconnects Cancer cell and Glioma in the investigation of issues within Oncolytic virus.
His work deals with themes such as Myxoma and Viral vector, which intersect with Virology. His work on Vaccinia expands to the thematically related Virus. His study on Tumor microenvironment is often connected to Soft tissue sarcoma as part of broader study in Cancer research.
Grant McFadden mainly investigates Oncolytic virus, Myxoma virus, Virology, Virus and Cancer research. He has included themes like Cancer cell and Ex vivo in his Oncolytic virus study. His study in Myxoma virus is interdisciplinary in nature, drawing from both Leporipoxvirus, Glioma, Metastasis, Cell killing and Receptor expression.
His work on Tropism, Viral replication and Host factor as part of general Virology study is frequently connected to Stress granule, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His Virus study integrates concerns from other disciplines, such as European rabbit, Vaccinia, Poxviridae and Virulence. His Cancer research research is multidisciplinary, relying on both Inflammasome, Uveitis, Lung cancer, Programmed cell death and Immunotherapy.
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Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB.
Morgan Sheng;Grant McFadden;Michael E. Greenberg.
Anti-Immunology: Evasion of the Host Immune System by Bacterial and Viral Pathogens
B. Brett Finlay;Grant McFadden.
Poxviruses and Immune Evasion
Bruce T. Seet;J.B. Johnston;Craig R. Brunetti;John W. Barrett.
Annual Review of Immunology (2003)
Apoptosis: an innate immune response to virus infection.
Helen Everett;Grant McFadden.
Trends in Microbiology (1999)
Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences.
M Sheng;S T Dougan;G McFadden;M E Greenberg.
Molecular and Cellular Biology (1988)
Encoding of a homolog of the IFN-gamma receptor by myxoma virus.
Chris Upton;Karen Mossman;Grant McFadden.
Neutrophils Recruited to Sites of Infection Protect from Virus Challenge by Releasing Neutrophil Extracellular Traps
Craig N Jenne;Connie Hoi Yee Wong;Franz J Zemp;Braedon McDonald.
Cell Host & Microbe (2013)
Modulation of NF-κB signalling by microbial pathogens
Masmudur M. Rahman;Grant McFadden.
Nature Reviews Microbiology (2011)
The T1/35kDa family of poxvirus-secreted proteins bind chemokines and modulate leukocyte influx into virus-infected tissues.
Kathryn A. Graham;Alshad S. Lalani;Joanne L. Macen;Traci L. Ness.
The complete DNA sequence of myxoma virus.
Cheryl Cameron;Cheryl Cameron;Sheela Hota-Mitchell;Ling Chen;John Barrett.
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