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Microbiology

D-Index
75
Citations
19398
World Ranking
1506
National Ranking
656

Overview

Klaus Früh is affiliated with Oregon Health & Science University in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a focus on Epidemiology, Immunology, Virology, Infectious Diseases, and Oncology.

The scientist's main topics of work include:

  • Cytomegalovirus and herpesvirus research
  • Immune Cell Function and Interaction
  • Herpesvirus Infections and Treatments
  • T-cell and B-cell Immunology
  • HIV Research and Treatment
  • Parvovirus B19 Infection Studies
  • Immunotherapy and Immune Responses

Frequent publication venues for Klaus Früh include:

  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science Immunology
  • PLoS Pathogens
  • Trends in Immunology

Frequent co-authors working with Klaus Früh are:

  • Daniel Malouli
  • Scott G. Hansen
  • Louis J. Picker
  • David Morrow
  • Husam Taher

Notable recent papers include:

  • Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy, 2021, Science
  • Cytomegaloviral determinants of CD8 + T cell programming and RhCMV/SIV vaccine efficacy, 2021, Science Immunology
  • HLA-E-restricted, Gag-specific CD8 + T cells can suppress HIV-1 infection, offering vaccine opportunities, 2021, Science Immunology
  • Programming cytomegalovirus as an HIV vaccine, 2023, Trends in Immunology
  • In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome, 2020, PLoS Pathogens

Best Publications

  • A viral inhibitor of peptide transporters for antigen presentation

    Klaus Früh;Kwangseog Ahn;Hakim Djaballah;Pascal Sempé

  • Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin.

    Marion Moos;Roland Tacke;Herta Scherer;David Teplow

  • Immune clearance of highly pathogenic SIV infection

    Scott G. Hansen;Michael Piatak;Abigail B. Ventura;Colette M. Hughes

  • The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP.

    Kwangseog Ahn;Albrecht Gruhler;Begona Galocha;Thomas R Jones

  • Human cytomegalovirus inhibits antigen presentation by a sequential multistep process

    Kwangseog Ahn;Ana Angulo;Peter Ghazal;Per A. Peterson

  • Cytomegalovirus Vectors Violate CD8+ T Cell Epitope Recognition Paradigms

    Scott G. Hansen;Jonah B. Sacha;Colette M. Hughes;Julia C. Ford

  • Vpu Directs the Degradation of the Human Immunodeficiency Virus Restriction Factor BST-2/Tetherin via a βTrCP-Dependent Mechanism

    Janet L. Douglas;Kasinath Viswanathan;Matthew N. McCarroll;Jean K. Gustin

  • Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47.

    Kwaangseog Ahn;Thomas H. Meyer;Stephan Uebel;Pascal Sempé

  • Interaction of MHC class I molecules with the transporter associated with antigen processing

    Woong Kyung Suh;Myrna F. Cohen-Doyle;Klaus Fruh;Kena Wang

  • Downregulation of Major Histocompatibility Complex Class I by Human Ubiquitin Ligases Related to Viral Immune Evasion Proteins

    Eric Bartee;Mandana Mansouri;Bianca T. Hovey Nerenberg;Kristine Gouveia

  • Antigen presentation by MHC class I and its regulation by interferon γ

    Klaus Früh;Young Yang

  • IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling

    Helen M. Lazear;Alissa Lancaster;Courtney Wilkins;Mehul S. Suthar;Mehul S. Suthar

  • Evasion of CD8+ T cells is critical for superinfection by cytomegalovirus.

    Scott G. Hansen;Colin J. Powers;Rebecca Richards;Abigail B. Ventura

  • Molecular Mechanism of BST2/Tetherin Downregulation by K5/MIR2 of Kaposi's Sarcoma-Associated Herpesvirus

    Mandana Mansouri;Kasinath Viswanathan;Janet L. Douglas;Jennie Hines

  • Broadly targeted CD8⁺ T cell responses restricted by major histocompatibility complex E.

    Scott G. Hansen;Helen L. Wu;Benjamin J. Burwitz;Colette M. Hughes

  • Displacement of housekeeping proteasome subunits by MHC-encoded LMPs: a newly discovered mechanism for modulating the multicatalytic proteinase complex.

    Klaus Früh;Manfred Gossen;Kena Wang;Hermann Bujard

  • Peptide length and sequence specificity of the mouse TAP1/TAP2 translocator.

    Ton N.M. Schumacher;Devang V. Kantesaria;Marie Therese Heemels;Philip G. Ashton-Rickardt

  • West Nile virus infection activates the unfolded protein response, leading to CHOP induction and apoptosis.

    Guruprasad R. Medigeshi;Alissa M. Lancaster;Alec J. Hirsch;Thomas Briese

  • Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine.

    Scott G Hansen;Daniel E Zak;Guangwu Xu;Julia C Ford

  • Quantitative membrane proteomics reveals new cellular targets of viral immune modulators.

    Eric Bartee;Ashley McCormack;Klaus Früh

  • In Vivo Assembly of the Proteasomal Complexes, Implications for Antigen Processing

    Young Yang;Klaus Früh;Kwangseog Ahn;Per A. Peterson

  • Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B

    Kenneth A. Simmen;Jasbir Singh;B. G. Mattias Luukkonen;Matt Lopper

Frequent Co-Authors

Louis J. Picker
Louis J. Picker Oregon Health & Science University
Michael K. Axthelm
Michael K. Axthelm Oregon National Primate Research Center
Jay A. Nelson
Jay A. Nelson Oregon Health & Science University
Jonah B. Sacha
Jonah B. Sacha Oregon Health & Science University
Per A. Peterson
Per A. Peterson Scripps Research Institute
Daniel N. Streblow
Daniel N. Streblow Oregon Health & Science University
Hermann Bujard
Hermann Bujard Heidelberg University
Andrea Crisanti
Andrea Crisanti University of Padua
Jacob D. Estes
Jacob D. Estes Oregon Health & Science University
Emmanuel J. H. J. Wiertz
Emmanuel J. H. J. Wiertz Utrecht University

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