Peter-M. Kloetzel

Overview

Best Publications

• Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells

  Annabell Bachem;Steffen Güttler;Evelyn Hartung;Frédéric Ebstein

  1162
  Citations

• Antigen processing by the proteasome

  Peter-M. Kloetzel

  878
  Citations

• The base of the proteasome regulatory particle exhibits chaperone-like activity.

  Beate C. Braun;Michael Glickman;Regine Kraft;Burkhardt Dahlmann

  705
  Citations

• Immunoproteasomes Preserve Protein Homeostasis upon Interferon-Induced Oxidative Stress

  Ulrike Seifert;Lukasz P. Bialy;Frédéric Ebstein;Dawadschargal Bech-Otschir

  620
  Citations

• A role for the proteasome regulator PA28α in antigen presentation

  Marcus Groettrup;Andrea Soza;Maren Eggers;Lothar Kuehn

  460
  Citations

• Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes.

  B Boes;H Hengel;T Ruppert;G Multhaup

  437
  Citations

• Green Tea Epigallocatechin-3-Gallate Mediates T Cellular NF-κB Inhibition and Exerts Neuroprotection in Autoimmune Encephalomyelitis

  Orhan Aktas;Timour Prozorovski;Alina Smorodchenko;Nicolai E. Savaskan

  402
  Citations

• Modeling the MHC class I pathway by combining predictions of proteasomal cleavage, TAP transport and MHC class I binding.

  S. Tenzer;B. Peters;S. Bulik;O. Schoor

  384
  Citations

• Coordinated Dual Cleavages Induced by the Proteasome Regulator PA28 Lead to Dominant MHC Ligands

  Tobias P. Dick;Thomas Ruppert;Marcus Groettrup;Peter M. Kloetzel

  372
  Citations

• IFN-γ-induced immune adaptation of the proteasome system is an accelerated and transient response

  Sylvia Heink;Daniela Ludwig;Peter-M. Kloetzel;Elke Krüger

  363
  Citations

• Inhibition of Proteasome Activity Induces Concerted Expression of Proteasome Genes and de Novo Formation of Mammalian Proteasomes

  Silke Meiners;Dirk Heyken;Andrea Weller;Antje Ludwig

  360
  Citations

• The role of the proteasome in the generation of MHC class I ligands and immune responses

  E. J. A. M. Sijts;P.-M. Kloetzel

  345
  Citations

• Interferon-gamma, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing.

  Britta Strehl;Ulrike Seifert;Elke Krüger;Sylvia Heink

  313
  Citations

• The Interferon-Gamma-inducible 11 S Regulator (PA28) and the LMP2/LMP7 Subunits Govern the Peptide Production by the 20 S Proteasome in Vitro

  Marcus Groettrup;Thomas Ruppert;Lothar Kuehn;Michael Seeger

  307
  Citations

• An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope.

  Ulrike Seifert;Concepcion Maranon;Ayelet Shmueli;Jean-Francois Desoutter

  299
  Citations

• Peptide antigen production by the proteasome: complexity provides efficiency

  Marcus Groettrup;Andrea Soza;Ulrike Kuckelkorn;Peter-M. Kloetzel

  290
  Citations

• The ubiquitin-domain protein HERP forms a complex with components of the endoplasmic reticulum associated degradation pathway.

  Andrea Schulze;Sybille Standera;Elke Buerger;Marjolein Kikkert

  286
  Citations

• Defined Flanking Spacers and Enhanced Proteolysis Is Essential for Eradication of Established Tumors by an Epitope String DNA Vaccine

  Markwin P. Velders;Sanne Weijzen;Gretchen L. Eiben;Amira G. Elmishad

  279
  Citations

• The proteasome and MHC class I antigen processing.

  Peter-M. Kloetzel

  270
  Citations

• Different proteasome subtypes in a single tissue exhibit different enzymatic properties

  Burkhardt Dahlmann;Thomas Ruppert;Lothar Kuehn;Simone Merforth

  267
  Citations