World's Best Scientists 2026 revealed!
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Animal Science and Veterinary
USA
2026

D-Index & Metrics

Animal Science and Veterinary

D-Index
95
Citations
28876
World Ranking
23
National Ranking
8

Immunology

D-Index
95
Citations
29017
World Ranking
911
National Ranking
503

Research.com Recognitions

  • 2026 - Research.com Animal Science and Veterinary in United States Leader Award
  • 2025 - Research.com Animal Science and Veterinary in United States Leader Award
  • 2023 - Research.com Animal Science and Veterinary in United States Leader Award

Overview

Barry T. Rouse is affiliated with the University of Tennessee at Knoxville in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a significant focus on subfields such as Immunology, Infectious Diseases, Epidemiology, Molecular Biology, and Cardiology and Cardiovascular Medicine.

The scientist's work addresses a variety of main topics, including:

  • COVID-19 Clinical Research Studies
  • Herpesvirus Infections and Treatments
  • SARS-CoV-2 and COVID-19 Research
  • Immune Cell Function and Interaction
  • Interferon and Immune Responses
  • Viral Infections and Immunology Research
  • Immune Response and Inflammation

Barry T. Rouse has contributed to multiple recent papers, among which are:

  • Host-Directed Antiviral Therapy, 2020, Clinical Microbiology Reviews
  • Virus Infections and Host Metabolism-Can We Manage the Interactions?, 2021, Frontiers in Immunology
  • Did Climate Change Influence the Emergence, Transmission, and Expression of the COVID-19 Pandemic?, 2021, Frontiers in Medicine
  • Supplementing the Diet with Sodium Propionate Suppresses the Severity of Viral Immuno-inflammatory Lesions, 2020, Journal of Virology
  • Climate change: how it impacts the emergence, transmission, resistance and consequences of viral infections in animals and plants, 2021, Critical Reviews in Microbiology

The scientist has published frequently in venues such as:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Microbes and Infection
  • Frontiers in Immunology
  • Clinical Microbiology Reviews
  • Journal of Virology

Collaborations feature prominently in their work, with frequent co-authors including Engin Berber, Deepak Sumbria, Sharvan Sehrawat, Naveen Kumar, and Shalini Sharma. These partnerships have contributed to advancing studies in their areas of research interest.

Best Publications

  • Natural regulatory T cells in infectious disease

    Yasmine Belkaid;Yasmine Belkaid;Barry T Rouse

  • CD4+CD25+ T Cells Regulate Virus-specific Primary and Memory CD8+ T Cell Responses

    Susmit Suvas;Uday Kumaraguru;Christopher D. Pack;Sujin Lee

  • Immunity and immunopathology to viruses: what decides the outcome?

    Barry T. Rouse;Sharvan Sehrawat

  • Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

    Henry Radziewicz;Chris C. Ibegbu;Marina L. Fernandez;Kimberly A. Workowski

  • Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsiveness.

    T. A. Banks;B. T. Rouse;M. K. Kerley;P. J. Blair

  • Target-sensitive immunoliposomes- preparation and characterization

    Leaf Huang

  • CD4+CD25+ regulatory T cells control the severity of viral immunoinflammatory lesions.

    Susmit Suvas;Ahmet Kursat Azkur;Bum Seok Kim;Uday Kumaraguru

  • Genetic immunization against herpes simplex virus. Protection is mediated by CD4+ T lymphocytes.

    E. Manickan;R. J. D. Rouse;Zhiya Yu;W. S. Wire

  • Inhibition of Ocular Angiogenesis by siRNA Targeting Vascular Endothelial Growth Factor Pathway Genes : Therapeutic Strategy for Herpetic Stromal Keratitis

    Bumseok Kim;Qingquan Tang;Partha S. Biswas;Jun Xu

  • Regulatory T cells in virus infections.

    Barry T. Rouse;Pranita P. Sarangi;Susmit Suvas

  • On the essential involvement of neutrophils in the immunopathologic disease: herpetic stromal keratitis.

    J Thomas;S Gangappa;S Kanangat;B T Rouse

  • Regression of tumors in mice vaccinated with professional antigen-presenting cells pulsed with tumor extracts.

    Smita K. Nair;David Snyder;Barry T. Rouse;Eli Gilboa

  • Soluble proteins delivered to dendritic cells via pH-sensitive liposomes induce primary cytotoxic T lymphocyte responses in vitro

    S Nair;F Zhou;R Reddy;L Huang

  • Induction of mucosal immunity against herpes simplex virus by plasmid DNA immunization.

    N Kuklin;M Daheshia;K Karem;E Manickan

  • Role of regulatory T cells during virus infection.

    Tamara Veiga-Parga;Sharvan Sehrawat;Barry T. Rouse

  • Predominance of Th1 cells in ocular tissues during herpetic stromal keratitis.

    M G Niemialtowski;B T Rouse

  • Contribution of Vascular Endothelial Growth Factor in the Neovascularization Process during the Pathogenesis of Herpetic Stromal Keratitis

    Mei Zheng;Shilpa Deshpande;Sujin Lee;Napoleone Ferrara

  • CD4+CD8- T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse.

    P J Blair;S J Bultman;J C Haas;B T Rouse

  • Immunosuppression in Viral Infections

    Barry T. Rouse;David W. Horohov

  • Herpes simplex virus-induced stromal keratitis: role of T-lymphocyte subsets in immunopathology.

    C K Newell;S Martin;D Sendele;C M Mercadal

  • Virological and Immunological Outcomes of Coinfections

    Naveen Kumar;Shalini Sharma;Sanjay Barua;Bhupendra N. Tripathi

  • Differentiation of memory B and T cells.

    Vandana Kalia;Surojit Sarkar;Tania S Gourley;Barry T Rouse

  • Early events in HSV keratitis—setting the stage for a blinding disease

    Partha S. Biswas;Barry T. Rouse

  • Role of T-lymphocytes in the pathogenesis of herpetic stromal keratitis.

    R G Russell;M P Nasisse;H S Larsen;B T Rouse

  • Cytotoxic T lymphocytes. Their relevance in herpesvirus infections.

    Stephen Martin;Ed Cantin;Barry T. Rouse

  • Role of matrix metalloproteinase-9 in angiogenesis caused by ocular infection with herpes simplex virus.

    Sujin Lee;Mei Zheng;Bumseok Kim;Barry T. Rouse

  • Enhancement of immune response to naked DNA vaccine by immunization with transfected dendritic cells.

    Eianchezhiyan Manickan;Sivadasan Kanangat;Richard J. D. Rouse;Zhiya Yu

  • Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response.

    Sharvan Sehrawat;Pradeep B J Reddy;Naveen K. Rajasagi;Amol Suryawanshi

Frequent Co-Authors

Smita Nair
Smita Nair Duke University
Leaf Huang
Leaf Huang University of North Carolina at Chapel Hill
Lorne A. Babiuk
Lorne A. Babiuk University of Alberta
Mitsuomi Hirashima
Mitsuomi Hirashima Kagawa University
Kevin L. Karem
Kevin L. Karem Centers for Disease Control and Prevention
Rafi Ahmed
Rafi Ahmed Emory University
Tim Sparwasser
Tim Sparwasser Johannes Gutenberg University of Mainz
Hermann Wagner
Hermann Wagner Technical University of Munich
Stefan H. E. Kaufmann
Stefan H. E. Kaufmann Max Planck Institute for Infection Biology
Scott N. Mueller
Scott N. Mueller University of Melbourne

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