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Immunology

D-Index
58
Citations
7533
World Ranking
3572
National Ranking
1654

Overview

Lbachir BenMohamed is affiliated with the University of California, Irvine in the United States. Their research primarily centers on medicine, with a significant focus on infectious diseases, epidemiology, and immunology, alongside contributions to molecular biology and neurology.

The scientist's work addresses multiple aspects of viral infections, immune responses, and vaccine development. Major themes in their research include SARS-CoV-2 and COVID-19 studies, herpesvirus infections and treatments, COVID-19 clinical research, long-term effects of COVID-19, cytomegalovirus and herpesvirus research, immunotherapy, and inflammation related to immune response.

The following papers reflect key recent contributions:

  • Genome-Wide B Cell, CD4+, and CD8+ T Cell Epitopes That Are Highly Conserved between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Targets for Preemptive Pan-Coronavirus Vaccines (2021, The Journal of Immunology)
  • SARS-CoV-2 Envelope (E) Protein Binds and Activates TLR2 Pathway: A Novel Molecular Target for COVID-19 Interventions (2022, Viruses)
  • Cross-protection induced by highly conserved human B, CD4+, and CD8+ T-cell epitopes-based vaccine against severe infection, disease, and death caused by multiple SARS-CoV-2 variants of concern (2024, Frontiers in Immunology)
  • Combinatorial Herpes Simplex Vaccine Strategies: From Bedside to Bench and Back (2022, Frontiers in Immunology)
  • High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4+ and CD8+ memory T cells are associated with protection from symptomatic and fatal SARS-CoV-2 infections in unvaccinated COVID-19 patients (2024, Frontiers in Immunology)

Frequently collaborating with other researchers, BenMohamed has worked extensively with Swayam Prakash, Hawa Vahed, Nisha R. Dhanushkodi, Afshana Quadiri, and Ruchi Srivastava, highlighting a network of academic partnerships.

BenMohamed has published in prominent scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory) with 20 publications
  • Frontiers in Immunology with 6 publications
  • Journal of Virology with 6 publications
  • The Journal of Immunology with 4 publications
  • Viruses with 3 publications

The scientist's fields of study demonstrate a comprehensive engagement with infectious diseases and related biomedical disciplines, as evidenced by 95 publications in medicine with notable work in infectious diseases (41), epidemiology (31), immunology (26), molecular biology (14), and neurology (10).

Best Publications

  • Lipopeptide vaccines—yesterday, today, and tomorrow

    Lbachir BenMohamed;Steven L Wechsler;Anthony B Nesburn

  • Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3.

    P. Daubersies;A.W. Thomas;P. Millet;K. Brahimi

  • A Fully Synthetic Therapeutic Vaccine Candidate Targeting Carcinoma-Associated Tn Carbohydrate Antigen Induces Tumor-Specific Antibodies in Nonhuman Primates

    Richard Lo-Man;Sophie Vichier-Guerre;Ronald Perraut;Edith Dériaud

  • The wide utility of rabbits as models of human diseases

    Pedro J. Esteves;Joana Abrantes;Hanna Mari Baldauf;Lbachir BenMohamed

  • Lipopeptide immunization without adjuvant induces potent and long-lasting B, T helper, and cytotoxic T lymphocyte responses against a malaria liver stage antigen in mice and chimpanzees

    Lbachir Benmohamed;Héléne Gras-Masse;André Tartar;Pierre Daubersies

  • Plasmodium falciparum liver stage antigen-1 is well conserved and contains potent B and T cell determinants

    D A Fidock;H Gras-Masse;J P Lepers;K Brahimi

  • HLA-A*0201-restricted CD8+ cytotoxic T lymphocyte epitopes identified from herpes simplex virus glycoprotein D

    Aziz Alami Chentoufi;Xiuli Zhang;Kasper Lamberth;Gargi Dasgupta

  • A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challenge.

    X Zhang;A A Chentoufi;G Dasgupta;A B Nesburn

  • Lipopeptide epitopes extended by an Nepsilon-palmitoyl-lysine moiety increase uptake and maturation of dendritic cells through a Toll-like receptor-2 pathway and trigger a Th1-dependent protective immunity.

    Xiaoming Zhu;Thomas V. Ramos;Helene Gras‐Masse;Bruce E. Kaplan

  • The Role of LAT in Increased CD8+ T Cell Exhaustion in Trigeminal Ganglia of Mice Latently Infected with Herpes Simplex Virus 1

    Sariah J. Allen;Pedram Hamrah;David M. Gate;Kevin R. Mott

  • Identification of Novel Immunodominant CD4+ Th1-Type T-Cell Peptide Epitopes from Herpes Simplex Virus Glycoprotein D That Confer Protective Immunity

    Lbachir BenMohamed;Georges Bertrand;Cory D. McNamara;Helene Gras-Masse

  • Towards a Self‐Adjuvanting Multivalent B and T cell Epitope Containing Synthetic Glycolipopeptide Cancer Vaccine

    Olivier Renaudet;Lbachir BenMohamed;Gargi Dasgupta;Ilham Bettahi

  • The Herpes Simplex Virus Type 1 Latency-Associated Transcript Can Protect Neuron-Derived C1300 and Neuro2A Cells from Granzyme B-Induced Apoptosis and CD8 T-Cell Killing

    Xianzhi Jiang;Aziz Alami Chentoufi;Chinhui Hsiang;Dale Carpenter

  • Level of Herpes Simplex Virus Type 1 Latency Correlates with Severity of Corneal Scarring and Exhaustion of CD8+ T Cells in Trigeminal Ganglia of Latently Infected Mice

    Kevin R. Mott;Catherine J. Bresee;Sariah J. Allen;Lbachir BenMohamed

  • Boosting Immunity to Small Tumor-Associated Carbohydrates with Bacteriophage Qβ Capsids

    Zhaojun Yin;Marta Comellas-Aragones;Sudipa Chowdhury;Philip Bentley

  • Th-cytotoxic T-lymphocyte chimeric epitopes extended by Nepsilon-palmitoyl lysines induce herpes simplex virus type 1-specific effector CD8+ Tc1 responses and protect against ocular infection.

    Xiuli Zhang;Annie Issagholian;Eric A. Berg;Jordan B. Fishman

  • A Novel HLA (HLA-A*0201) Transgenic Rabbit Model for Preclinical Evaluation of Human CD8+ T Cell Epitope-Based Vaccines against Ocular Herpes

    Aziz A. Chentoufi;Gargi Dasgupta;Neil D. Christensen;Jiafen Hu

  • High immunogenicity in chimpanzees of peptides and lipopeptides derived from four new Plasmodium falciparum pre-erythrocytic molecules.

    Lbachir Benmohamed;Alan Thomas;Marc Bossus;Karima Brahimi

  • A novel Plasmodium falciparum sporozoite and liver stage antigen (SALSA) defines major B, T helper, and CTL epitopes.

    E Bottius;L BenMohamed;K Brahimi;H Gras

  • Systemic immune responses induced by mucosal administration of lipopeptides without adjuvant

    Lbachir BenMohamed;Yasmine Belkaid;Estelle Loing;Karima Brahimi

Frequent Co-Authors

Anthony B. Nesburn
Anthony B. Nesburn University of California, Irvine
Steven L. Wechsler
Steven L. Wechsler University of California, Irvine
Pierre Druilhe
Pierre Druilhe Institut Pasteur
Clinton Jones
Clinton Jones Oklahoma State University
James V. Jester
James V. Jester University of California, Irvine
Guey Chuen Perng
Guey Chuen Perng National Cheng Kung University
John Sidney
John Sidney La Jolla Institute For Allergy & Immunology
Alan W. Thomas
Alan W. Thomas Biomedical Primate Research Centre
Neil D. Christensen
Neil D. Christensen Pennsylvania State University
Laura E. Via
Laura E. Via National Institutes of Health

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