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Benoît Van den Eynde

Benoît Van den Eynde

D-Index & Metrics

Immunology

D-Index
78
Citations
24519
World Ranking
1740
National Ranking
23

Medicine

D-Index
78
Citations
24578
World Ranking
17976
National Ranking
227

Overview

Benoît Van den Eynde is affiliated with Ludwig Cancer Research in Belgium. Their research spans multiple areas within the biomedical sciences, focusing primarily on medicine, immunology, and molecular biology.

The main fields of study of Benoît Van den Eynde include:

  • Medicine
  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Subfields of study feature a concentration in oncology and immunology, with additional work in molecular biology and biological psychiatry. Specific subfields include:

  • Oncology
  • Immunology
  • Molecular Biology
  • Biological Psychiatry
  • Psychiatry and Mental Health

The primary research topics covered in Van den Eynde's work focus on immune mechanisms and cancer therapies with detail on immune responses and cell function. Major topics include:

  • Immunotherapy and Immune Responses
  • Cancer Immunotherapy and Biomarkers
  • Immune Cell Function and Interaction
  • CAR-T Cell Therapy Research
  • Tryptophan and Brain Disorders
  • Cancer, Stress, Anesthesia, and Immune Response
  • Ubiquitin and Proteasome Pathways

Recent publications illustrate the diversity and scope of Van den Eynde's research contributions. Selected recent papers include:

  • Preclinical murine tumor models: A structural and functional perspective, 2020, eLife
  • Tumour immune rejection triggered by activation of α2-adrenergic receptors, 2023, Nature
  • Systemic tryptophan homeostasis, 2022, Frontiers in Molecular Biosciences
  • Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression, 2023, Journal for ImmunoTherapy of Cancer
  • Functional Differences between Proteasome Subtypes, 2022, Cells

Benoît Van den Eynde frequently collaborates with several co-authors, reflecting a network of scientific partnerships. Frequent co-authors include:

  • Jingjing Zhu
  • Stefan Naulaerts
  • Vincent Stroobant
  • Carol S. Leung
  • Nathalie Vigneron

The scientist's work is regularly published in journals emphasizing cancer immunotherapy and translational research. Frequent publication venues include:

  • Journal for ImmunoTherapy of Cancer
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Immunology Research
  • Zenodo (CERN European Organization for Nuclear Research)
  • Science Translational Medicine

Best Publications

  • Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

    Catherine Uyttenhove;Luc Pilotte;Ivan Théate;Ivan Théate;Vincent Stroobant

  • Tumor-antigens recognized by T-lymphocytes

    Thierry Boon;Jean-Charles Cerottini;Benoît Van den Eynde;Pierre van der Bruggen

  • Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy.

    Pierre G. Coulie;Benoît J. Van den Eynde;Pierre van der Bruggen;Thierry Boon

  • HUMAN T CELL RESPONSES AGAINST MELANOMA

    Thierry Boon;Pierre G Coulie;Benoît J Van den Eynde;Pierre van der Bruggen

  • T cell defined tumor antigens

    Benoît J Van den Eynde;Pierre van der Bruggen

  • Tryptophan catabolism in cancer: beyond IDO and tryptophan depletion.

    Michael Platten;Wolfgang Wick;Benoît J. Van den Eynde;Benoît J. Van den Eynde

  • Tumor antigens recognized by T cells

    Thierry Boon;Pierre G. Coulie;Benoît Van den Eynde

  • Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

    Luc Pilotte;Pierre Larrieu;Vincent Stroobant;Didier Colau

  • Classification of current anticancer immunotherapies

    Lorenzo Galluzzi;Erika Vacchelli;José Manuel Bravo-San Pedro;Aitziber Buqué

  • Tumor-specific shared antigenic peptides recognized by human T cells

    Pierre van der Bruggen;Yi Zhang;Pascal Chaux;Vincent Stroobant

  • Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells.

    Sandra Morel;Frédéric Lévy;Odile Burlet-Schiltz;Francis Brasseur

  • An Antigenic Peptide Produced by Peptide Splicing in the Proteasome

    Nathalie Vigneron;Vincent Stroobant;Jacques Chapiro;Annie Ooms

  • Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death

    Abhishek D. Garg;Lorenzo Galluzzi;Lionel Apetoh;Lionel Apetoh;Thais Baert

  • Extensive Profiling of the Expression of the Indoleamine 2,3-Dioxygenase 1 Protein in Normal and Tumoral Human Tissues

    Ivan Théate;Ivan Théate;Nicolas van Baren;Nicolas van Baren;Luc Pilotte;Luc Pilotte;Pierre Moulin

  • Integrating Next-Generation Dendritic Cell Vaccines into the Current Cancer Immunotherapy Landscape

    Abhishek D. Garg;Pierre G. Coulie;Benoit J. Van den Eynde;Patrizia Agostinis

  • Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules

    Benoît Guillaume;Jacques Chapiro;Vincent Stroobant;Didier Colau

  • Differential processing of class-I-restricted epitopes by the standard proteasome and the immunoproteasome

    Benoı̂t J Van den Eynde;Sandra Morel

  • An antigen produced by splicing of noncontiguous peptides in the reverse order

    Edus H. Warren;Edus H. Warren;Nathalie J. Vigneron;Nathalie J. Vigneron;Marc A. Gavin;Marc A. Gavin;Pierre G. Coulie

  • Resistance to cancer immunotherapy mediated by apoptosis of tumor-infiltrating lymphocytes.

    Jingjing Zhu;Jingjing Zhu;Céline G. Powis de Tenbossche;Céline G. Powis de Tenbossche;Stefania Cané;Stefania Cané;Didier Colau;Didier Colau

  • Antigen Spreading Contributes to MAGE Vaccination-Induced Regression of Melanoma Metastases

    Véronique Corbière;Jacques Chapiro;Vincent Stroobant;Wenbin Ma

  • A new gene coding for an antigen recognized by autologous cytolytic T lymphocytes on a human renal carcinoma.

    Béatrice Gaugler;Nathalie Brouwenstijn;Valérie Vantomme;Jean-Pierre Szikora

  • Reversal of Tumoral Immune Resistance by Inhibition of Tryptophan 2,3-Dioxygenase (TDO): Design, Synthesis and Preclinical Evaluation of a Novel TDO Inhibitor.

    Eduard Dolušić;Pierre Larrieu;Laurence Moineaux;Vincent Stroobant

Frequent Co-Authors

Pierre van der Bruggen
Pierre van der Bruggen Université Catholique de Louvain
Thierry Boon
Thierry Boon Ludwig Cancer Research
Vincent Stroobant
Vincent Stroobant Ludwig Cancer Research
Pierre Coulie
Pierre Coulie Université Catholique de Louvain
Johan Wouters
Johan Wouters University of Namur
Catherine Uyttenhove
Catherine Uyttenhove Ludwig Cancer Research
Francis Brasseur
Francis Brasseur Ludwig Cancer Research
Catia Traversari
Catia Traversari MolMed (Italy)
Moreno Galleni
Moreno Galleni University of Liège
Anne-Marie Schmitt-Verhulst
Anne-Marie Schmitt-Verhulst Centre d’Immunologie de Marseille-Luminy

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