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Moreno Galleni

Moreno Galleni

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
13298
World Ranking
8816
National Ranking
154

Overview

Moreno Galleni is affiliated with the University of Liège in Belgium. Their research portfolio predominantly spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine, with significant work in related subfields such as Molecular Medicine, Molecular Biology, Pharmacology, Infectious Diseases, and Epidemiology.

The scientist's work focuses on several core topics, including:

  • Antibiotic Resistance in Bacteria
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Tuberculosis Research and Epidemiology
  • Antibiotics Pharmacokinetics and Efficacy
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Genomics and Phylogenetic Studies
  • Monoclonal and Polyclonal Antibodies Research

Galleni has contributed extensively to the scientific literature, with a notable presence in journals such as Antimicrobial Agents and Chemotherapy, bioRxiv (Cold Spring Harbor Laboratory), Microbiology Spectrum, European Journal of Medicinal Chemistry, and Biomolecules. The following is a selection of recent papers authored or coauthored by them, highlighting diverse aspects of metallo-β-lactamase inhibitors and bacterial enzyme research:

  • 4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors, 2020, European Journal of Medicinal Chemistry
  • 4-(N-Alkyl- and -Acyl-amino)-1,2,4-triazole-3-thione Analogs as Metallo-β-Lactamase Inhibitors: Impact of 4-Linker on Potency and Spectrum of Inhibition, 2020, Biomolecules
  • di-Cysteine Residues of the Arabidopsis thaliana HMA4 C-Terminus Are Only Partially Required for Cadmium Transport, 2020, Frontiers in Plant Science
  • 4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors, 2021, Bioorganic Chemistry
  • An Extended Reservoir of Class-D Beta-Lactamases in Non-Clinical Bacterial Strains, 2022, Microbiology Spectrum

The scientist has frequently collaborated with colleagues such as Paola Sandra Mercuri, Frédéric Kerff, Laurent Gavara, Laurent Sevaille, and Filomena De Luca, producing a body of work marked by repeated partnerships.

Galleni's publication venues reflect a breadth of engagement with the scientific community, with the most publications appearing in Antimicrobial Agents and Chemotherapy (4 works), followed by bioRxiv (3 works) and Microbiology Spectrum (2 works).

Best Publications

  • The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold.

    A. Carfi;S. Pares;E. Duée;Moreno Galleni

  • Standard Numbering Scheme for Class B β-Lactamases

    Moreno Galleni;Josette Lamotte-Brasseur;Gian Maria Rossolini;Jim Spencer

  • Beta-lactamase inhibitors derived from single-domain antibody fragments elicited in the camelidae.

    Katja E. Conrath;Marc Lauwereys;Moreno Galleni;André Matagne

  • Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor.

    Néstor O. Concha;Cheryl A. Janson;Pam Rowling;Stewart Pearson

  • Update of the Standard Numbering Scheme for Class B β-Lactamases

    Gianpiero Garau;Isabel García-Sáez;Carine Bebrone;Christine Anne

  • Biochemical characterization of the Pseudomonas aeruginosa 101/1477 metallo-beta-lactamase IMP-1 produced by Escherichia coli.

    Nezha Laraki;Nicola Franceschini;Gian Maria Rossolini;Pasqualino Santucci

  • A metallo-beta-lactamase enzyme in action: crystal structures of the monozinc carbapenemase CphA and its complex with biapenem.

    Gianpiero Garau;Carine Bebrone;Christine Anne;Moreno Galleni

  • The beta-lactamase cycle: a tale of selective pressure and bacterial ingenuity.

    André Matagne;Alain Dubus;Moreno Galleni;Jean-Marie Frère

  • Zn(Ii) Dependence of the Aeromonas Hydrophila Ae036 Metallo-Beta-Lactamase Activity and Stability

    M. Hernandez Valladares;A. Felici;Georges Weber;H. W. Adolph

  • Metallo-β-lactamases as emerging resistance determinants in Gram-negative pathogens: open issues

    Giuseppe Cornaglia;Murat Akova;Gianfranco Amicosante;Rafael Cantón

  • Structure of In31, a blaIMP-containing Pseudomonas aeruginosa integron phyletically related to In5, which carries an unusual array of gene cassettes

    Nezha Laraki;Moreno Galleni;Iris Thamm;Maria Letizia Riccio

  • Chromosome-Encoded CTX-M-3 from Kluyvera ascorbata: a Possible Origin of Plasmid-Borne CTX-M-1-Derived Cefotaximases

    María Margarita Rodríguez;Pablo Power;Marcela Radice;Carlos Vay

  • A survey of the kinetic parameters of class C beta-lactamases. Cephalosporins and other beta-lactam compounds.

    Moreno Galleni;G. Amicosante;Jean-Marie Frère

  • Sequence and comparative analysis of three Enterobacter cloacae ampC beta-lactamase genes and their products.

    Moreno Galleni;F. Lindberg;S. Normark;S. Cole

  • 1.85 A resolution structure of the zinc (II) beta-lactamase from Bacillus cereus.

    Andrea Carfi;Emile Duée;Moreno Galleni;Jean-Marie Frère

  • Polyolefin matrixes with permanent antibacterial activity: preparation, antibacterial activity, and action mode of the active species

    Sandrine Lenoir;Christophe Pagnoulle;Moreno Galleni;Philippe Compère

  • Metal ion binding and coordination geometry for wild type and mutants of metallo-beta -lactamase from Bacillus cereus 569/H/9 (BcII): a combined thermodynamic, kinetic, and spectroscopic approach.

    Dominique de Seny;Uwe Heinz;Sandra Wommer;Martin Kiefer

  • CENTA as a Chromogenic Substrate for Studying β-Lactamases

    Carine Bebrone;Catherine Moali;Florence Mahy;Sandrine Rival

  • Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-β-lactamases

    Patricia Lassaux;Matthieu Hamel;Mihaela Gulea;Heinrich Delbrück

  • The 1.5-Å Structure of Chryseobacterium meningosepticum Zinc β-Lactamase in Complex with the Inhibitor, D-Captopril

    Isabel García-Sáez;Julie Hopkins;Cyril Papamicael;Nicola Franceschini

Frequent Co-Authors

Jean-Marie Frère
Jean-Marie Frère University of Liège
Gianfranco Amicosante
Gianfranco Amicosante University of L'Aquila
Gian Maria Rossolini
Gian Maria Rossolini University of Florence
Otto Dideberg
Otto Dideberg Centre national de la recherche scientifique, CNRS
Bernard Joris
Bernard Joris University of Liège
Johan Wouters
Johan Wouters University of Namur
Benoît Van den Eynde
Benoît Van den Eynde Ludwig Cancer Research
Jozef Van Beeumen
Jozef Van Beeumen Ghent University
Bart Devreese
Bart Devreese Ghent University
Jean Denis Docquier
Jean Denis Docquier University of Siena

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