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Immunology

D-Index
71
Citations
20370
World Ranking
2298
National Ranking
29

Overview

Pierre van der Bruggen is affiliated with Université Catholique de Louvain in Belgium and specializes in research at the intersection of immunology, microbiology, and medicine. Their scholarly work primarily focuses on immune cells in cancer and immunotherapy, targeting mechanisms involving immune cell function and interaction as well as galectins and cancer biology.

Their main research fields include:

  • Immunology and Microbiology
  • Medicine

Van der Bruggen's subfields of study encompass:

  • Immunology
  • Oncology
  • Molecular Biology
  • Radiology, Nuclear Medicine and Imaging
  • Cell Biology

Key topics covered in their research are:

  • Immune cells in cancer
  • Immune Cell Function and Interaction
  • Galectins and Cancer Biology
  • Immunotherapy and Immune Responses
  • Immune Response and Inflammation
  • CAR-T cell therapy research
  • T-cell and B-cell Immunology

They have contributed to several peer-reviewed papers including:

  • "Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166," 2020, published in Nature Communications
  • "A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability," 2020, Cancer Research
  • "MDSC in Mice and Men: Mechanisms of Immunosuppression in Cancer," 2021, Journal of Clinical Medicine
  • "Identification of an Immature Subset of PMN-MDSC Correlated to Response to Checkpoint Inhibitor Therapy in Patients with Metastatic Melanoma," 2021, Cancers
  • "Immunosuppressive low-density neutrophils in the blood of cancer patients display a mature phenotype," 2023, Life Science Alliance

Frequent collaborators include:

  • Thibault Hirsch
  • Christophe Vanhaver
  • Alexandre Bayard
  • Annika M. Bruger
  • Mathieu Luyckx

Van der Bruggen's research has been disseminated in various scientific journals, with repeated publications in venues such as Nature Communications, Cancer Research, Journal of Clinical Medicine, Life Science Alliance, and Cell Reports.

Best Publications

  • Tumor-antigens recognized by T-lymphocytes

    Thierry Boon;Jean-Charles Cerottini;Benoît Van den Eynde;Pierre van der Bruggen

  • Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy.

    Pierre G. Coulie;Benoît J. Van den Eynde;Pierre van der Bruggen;Thierry Boon

  • Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1

    M Marchand;N van Baren;N van Baren;P Weynants;P Weynants;V Brichard;V Brichard;V Brichard

  • Structure, Chromosomal Localization, and Expression of 12 Genes of the Mage Family

    Etienne De Plaen;Etienne De Plaen;Catia Traversari;Catia Traversari;José J.J. Gaforio;José J.J. Gaforio;Jean Pierre Szikora;Jean Pierre Szikora

  • HUMAN T CELL RESPONSES AGAINST MELANOMA

    Thierry Boon;Pierre G Coulie;Benoît J Van den Eynde;Pierre van der Bruggen

  • T cell defined tumor antigens

    Benoît J Van den Eynde;Pierre van der Bruggen

  • Bage - a New Gene Encoding An Antigen Recognized On Human Melanomas By Cytolytic T-lymphocytes

    Pascale Boël;Claude Wildmann;Maria Luisa Sensi;Robert Brasseur

  • Tumor-specific shared antigenic peptides recognized by human T cells

    Pierre van der Bruggen;Yi Zhang;Pascal Chaux;Vincent Stroobant

  • A peptide encoded by human gene MAGE-3 and presented by HLA-A2 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE-3.

    P van der Bruggen;J Bastin;T Gajewski;T Gajewski;P G Coulie

  • A CASP-8 Mutation Recognized by Cytolytic T Lymphocytes on a Human Head and Neck Carcinoma

    Susanna Mandruzzato;Francis Brasseur;Guy Andry;Thierry Boon

  • An Antigenic Peptide Produced by Peptide Splicing in the Proteasome

    Nathalie Vigneron;Vincent Stroobant;Jacques Chapiro;Annie Ooms

  • Identification of MAGE-3 Epitopes Presented by HLA-DR Molecules to CD4+ T Lymphocytes

    Pascal Chaux;Valérie Vantomme;Vincent Stroobant;Kris Thielemans

  • Autologous Human Monocyte-Derived Dendritic Cells Genetically Modified to Express Melanoma Antigens Elicit Primary Cytotoxic T Cell Responses In Vitro: Enhancement by Cotransfection of Genes Encoding the Th1-Biasing Cytokines IL-12 and IFN-α

    Thomas Tüting;Cara C. Wilson;Dina M. Martin;Yvette L. Kasamon

  • Genes coding for tumor-antigens recognized by cytolytic T-lymphocytes

    Aline Van Pel;Pierre Van Der Bruggen;Pierre G. Coulie;Vincent G. Brichard

  • Autologous cytolytic T lymphocytes recognize a MAGE-1 nonapeptide on melanomas expressing HLA-Cw*1601

    Pierre Van Der Bruggen;Jean Pierre Szikora;Pascale Boël;Claude Wildmann

  • Treatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II-Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3.

    Yong Chen Lu;Linda L. Parker;Tangying Lu;Zhili Zheng

  • Messenger RNA-electroporated dendritic cells presenting MAGE-A3 simultaneously in HLA class I and class II molecules.

    Aude Bonehill;Carlo Heirman;Sandra Tuyaerts;Annelies Michiels

  • Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients

    Aude Bonehill;An M.T. Van Nuffel;Jurgen Corthals;Sandra Tuyaerts

  • Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes.

    Nathalie Demotte;Nathalie Demotte;Vincent Stroobant;Vincent Stroobant;Pierre J. Courtoy;Patrick Van Der Smissen

  • Database of T cell-defined human tumor antigens: the 2013 update.

    Nathalie Vigneron;Vincent Stroobant;Vincent Stroobant;Benoît J. Van den Eynde;Benoît J. Van den Eynde;Pierre van der Bruggen;Pierre van der Bruggen

  • Characterization of the GAGE genes that are expressed in various human cancers and in normal testis.

    Olivier De Backer;Karen C. Arden;Mauro Boretti;Valérie Vantomme

  • Human Gene MAGE-3 Codes for an Antigen Recognized on a Melanoma by Autologous Cytolytic T Lymphocytes By Btatrice Gaugler,* Benoit Van den Eynde,*

    Pierre van der Bruggen;Pedro Romero;Jose Juan Gaforio;Etienne De Plaen

Frequent Co-Authors

Thierry Boon
Thierry Boon Ludwig Cancer Research
Benoît Van den Eynde
Benoît Van den Eynde Ludwig Cancer Research
Pierre Coulie
Pierre Coulie Université Catholique de Louvain
Vincent Stroobant
Vincent Stroobant Ludwig Cancer Research
Kris Thielemans
Kris Thielemans Vrije Universiteit Brussel
Francis Brasseur
Francis Brasseur Ludwig Cancer Research
Catia Traversari
Catia Traversari MolMed (Italy)
Carlo Heirman
Carlo Heirman Vrije Universiteit Brussel
Jean-Christophe Renauld
Jean-Christophe Renauld Université Catholique de Louvain
Gerold Schuler
Gerold Schuler University of Erlangen-Nuremberg

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Related Online Degrees & Career Pathways

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