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Immunology

D-Index
65
Citations
12466
World Ranking
2875
National Ranking
38

Overview

Karine Breckpot is affiliated with Vrije Universiteit Brussel in Belgium. Their research spans multiple fields within biomedical sciences, with a focus on Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology.

Their work covers a variety of subfields including Immunology, Oncology, Molecular Biology, Radiology, Nuclear Medicine and Imaging, and Genetics.

Key topics of their research include:

  • Immunotherapy and Immune Responses
  • Monoclonal and Polyclonal Antibodies Research
  • CAR-T cell therapy research
  • Cancer Immunotherapy and Biomarkers
  • Immune Cell Function and Interaction
  • RNA Interference and Gene Delivery
  • Radiopharmaceutical Chemistry and Applications

Karine Breckpot's frequent co-authors have included:

  • Nick Devoogdt
  • Cleo Goyvaerts
  • Marleen Keyaerts
  • Kim De Veirman
  • Thomas Ertveldt

Their publications have appeared predominantly in venues such as:

  • Frontiers in Immunology
  • International Journal of Molecular Sciences
  • Journal of Nuclear Medicine
  • Journal of Controlled Release
  • Journal for ImmunoTherapy of Cancer

Among their recent papers are:

  • "Immunogenicity Risk Profile of Nanobodies" (2021, Frontiers in Immunology)
  • "The Next-Generation Immune Checkpoint LAG-3 and Its Therapeutic Potential in Oncology: Third Time's a Charm" (2020, International Journal of Molecular Sciences)
  • "Challenges in neoantigen-directed therapeutics" (2022, Cancer Cell)
  • "mRNA-LNP vaccines tuned for systemic immunization induce strong antitumor immunity by engaging splenic immune cells" (2022, Molecular Therapy)
  • "Neo-Antigen mRNA Vaccines" (2020, Vaccines)

Best Publications

  • Consensus guidelines for the detection of immunogenic cell death

    Oliver Kepp;Laura Senovilla;Ilio Vitale;Erika Vacchelli

  • Lentiviral vectors in gene therapy: their current status and future potential.

    David Escors;Karine Breckpot;Karine Breckpot

  • Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death

    Abhishek D. Garg;Lorenzo Galluzzi;Lionel Apetoh;Lionel Apetoh;Thais Baert

  • Combinatorial Strategies for the Induction of Immunogenic Cell Death

    Lucillia Bezu;Ligia C. Gomes-de-Silva;Heleen Dewitte;Karine Breckpot

  • PDL1 Signals through Conserved Sequence Motifs to Overcome Interferon-Mediated Cytotoxicity.

    Maria Gato-Cañas;Miren Zuazo;Hugo Arasanz;Maria Ibañez-Vea

  • Nanobody-Based Targeting of the Macrophage Mannose Receptor for Effective In Vivo Imaging of Tumor-Associated Macrophages

    Kiavash Movahedi;Steve Schoonooghe;Damya Laoui;Isabelle Houbracken

  • PD1 signal transduction pathways in T cells

    Hugo Arasanz;Maria Gato-Cañas;Miren Zuazo;Maria Ibañez-Vea

  • CD83 expression on dendritic cells and T cells: correlation with effective immune responses.

    Cindy Aerts-Toegaert;Carlo Heirman;Sandra Tuyaerts;Jurgen Corthals

  • Messenger RNA-electroporated dendritic cells presenting MAGE-A3 simultaneously in HLA class I and class II molecules.

    Aude Bonehill;Carlo Heirman;Sandra Tuyaerts;Annelies Michiels

  • Preclinical Evaluation of TriMix and Antigen mRNA-Based Antitumor Therapy

    Sandra Van Lint;Cleo Goyvaerts;Sarah Maenhout;Lode Goethals

  • Current approaches in dendritic cell generation and future implications for cancer immunotherapy.

    Sandra Tuyaerts;Joeri L. Aerts;Jurgen Corthals;Bart Neyns

  • Lentivirally transduced dendritic cells as a tool for cancer immunotherapy.

    Karine Breckpot;Melissa Dullaers;Aude Bonehill;Sonja Van Meirvenne

  • Role of non-classical MHC class I molecules in cancer immunosuppression

    Grazyna Kochan;David Escors;Karine Breckpot;David Guerrero-Setas

  • Turn Back the TIMe: Targeting Tumor Infiltrating Myeloid Cells to Revert Cancer Progression

    Robin Maximilian Awad;Yannick De Vlaeminck;Johannes Maebe;Cleo Goyvaerts

  • mRNA-based dendritic cell vaccines

    Daphné Benteyn;Carlo Heirman;Aude Bonehill;Kris Thielemans

  • Immunogenicity Risk Profile of Nanobodies

    Chloé Ackaert;Natalia Smiejkowska;Catarina Xavier;Yann G J Sterckx;Yann G J Sterckx

  • Lentiviral vectors for cancer immunotherapy: transforming infectious particles into therapeutics.

    Karine Breckpot;Joeri Aerts;Kris Thielemans

  • mRNA-LNP vaccines tuned for systemic immunization induce strong antitumor immunity by engaging splenic immune cells

    Unknown

  • HIV-1 Lentiviral vector immunogenicity is mediated by Toll-Like Receptor 3 (TLR3) and TLR7

    Karine Breckpot;David Escors;Frederick Arce;Lucienne Lopes

  • Generation of large numbers of dendritic cells in a closed system using Cell Factories.

    Sandra Tuyaerts;Sofie M. Noppe;Jurgen Corthals;Karine Breckpot

  • Dynamic bioluminescence imaging for quantitative tumour burden assessment using IV or IP administration of D: -luciferin: effect on intensity, time kinetics and repeatability of photon emission

    Marleen Keyaerts;Jacob Verschueren;Tomas J. Bos;Lea Olive Tchouate-Gainkam

Frequent Co-Authors

Carlo Heirman
Carlo Heirman Vrije Universiteit Brussel
Kris Thielemans
Kris Thielemans Vrije Universiteit Brussel
Geert Raes
Geert Raes Vrije Universiteit Brussel
Stefaan C. De Smedt
Stefaan C. De Smedt Ghent University
Patrick De Baetselier
Patrick De Baetselier Vrije Universiteit Brussel
Jo A. Van Ginderachter
Jo A. Van Ginderachter Vrije Universiteit Brussel
Karin Vanderkerken
Karin Vanderkerken Vrije Universiteit Brussel
Oliver Kepp
Oliver Kepp Institut Gustave Roussy
Serge Muyldermans
Serge Muyldermans Vrije Universiteit Brussel
Guido Kroemer
Guido Kroemer Université Paris Cité

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Related Online Degrees & Career Pathways

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