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Patrick De Baetselier

Patrick De Baetselier

D-Index & Metrics

Immunology

D-Index
86
Citations
25335
World Ranking
1273
National Ranking
15

Medicine

D-Index
86
Citations
26066
World Ranking
14174
National Ranking
178

Overview

Patrick De Baetselier is affiliated with the Vrije Universiteit Brussel in Belgium and specializes in immunology and microbiology, with a particular focus on the interactions between parasites and host immune responses. Their research spans fields including immunology, epidemiology, molecular biology, parasitology, and public health.

The scientist's recent publications include studies on the functions and regulation of immune cells during infections and cancer. Notable papers are:

  • "Ontogeny, functions and reprogramming of Kupffer cells upon infectious disease" (2023) published in Frontiers in Immunology
  • "The Role of MIF and IL-10 as Molecular Yin-Yang in the Modulation of the Host Immune Microenvironment During Infections: African Trypanosome Infections as a Paradigm" (2022) published in Frontiers in Immunology
  • "Infection history imprints prolonged changes to the epigenome, transcriptome and function of Kupffer cells" (2024) published in Journal of Hepatology
  • "Monocytic myeloid-derived suppressor cells home to tumor-draining lymph nodes via CCR2 and locally modulate the immune response" (2021) published in Cellular Immunology
  • "Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection" (2020) published in PLoS Pathogens

The core topics of Patrick De Baetselier's research include Trypanosoma species and their implications, immune cells involvement in cancer, macrophage migration inhibitory factor, parasites and host interactions, leishmaniasis studies, immune response and inflammation, and sphingolipid metabolism and signaling.

Coauthors frequently collaborating with Patrick De Baetselier include Jo A. Van Ginderachter, Benoît Stijlemans, Kiavash Movahedi, Stefan Magez, and Carl De Trez.

Publications have appeared predominantly in venues such as Frontiers in Immunology, PLoS Pathogens, Journal of Hepatology, Nature Communications, and Cellular Immunology.

Best Publications

  • Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell–suppressive activity

    Kiavash Movahedi;Martin Guilliams;Jan Van den Bossche;Rafael Van den Bergh

  • Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

    Kiavash Movahedi;Damya Laoui;Conny Gysemans;Martijn Baeten

  • Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

    Charlotte L Scott;Fang Zheng;Fang Zheng;Patrick De Baetselier;Liesbet Martens

  • Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor κB

    Chiara Porta;Monica Rimoldi;Geert Raes;Lea Brys

  • Apolipoprotein L-I is the trypanosome lytic factor of human serum

    Luc Vanhamme;Françoise Paturiaux-Hanocq;Philippe Poelvoorde;Derek P. Nolan;Derek P. Nolan

  • Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages

    Geert Raes;Patrick De Baetselier;Wim Noël;Alain Beschin

  • Efficient Cancer Therapy with a Nanobody-Based Conjugate

    Virna Cortez-Retamozo;Natalija Backmann;Peter D. Senter;Ullrich Wernery

  • A VSG Expression Site-Associated Gene Confers Resistance to Human Serum in Trypanosoma rhodesiense

    Hoang Van Xong;Luc Vanhamme;Mustapha Chamekh;Chibeka Evelyn Chimfwembe

  • Classical and alternative activation of mononuclear phagocytes: picking the best of both worlds for tumor promotion.

    Jo A. Van Ginderachter;Kiavash Movahedi;Gholamreza Hassanzadeh Ghassabeh;Sofie Meerschaut

  • Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population

    Damya Laoui;Eva Van Overmeire;Giusy Di Conza;Chiara Aldeni

  • Efficient tumor targeting by single-domain antibody fragments of camels.

    Virna Cortez-Retamozo;Marc Lauwereys;Gholamreza Hassanzadeh Gh.;Martine Gobert

  • Alternatively activated macrophages during parasite infections.

    Wim Noël;Geert Raes;Gholamreza Hassanzadeh Ghassabeh;Patrick De Baetselier

  • Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions

    Damya Laoui;Kiavash Movahedi;Eva Van Overmeire;Jan Van den Bossche

  • Nanobodies as novel agents for cancer therapy

    Hilde Revets;Patrick De Baetselier;Serge Muyldermans

  • Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm

    Benoît Stijlemans;Katja Conrath;Virna Cortez-Retamozo;Hoang Van Xong

  • Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells.

    Geert Raes;Rafaël Van den Bergh;Patrick De Baetselier;Gholamreza Hassanzadeh Ghassabeh

  • Nanobody-Based Targeting of the Macrophage Mannose Receptor for Effective In Vivo Imaging of Tumor-Associated Macrophages

    Kiavash Movahedi;Steve Schoonooghe;Damya Laoui;Isabelle Houbracken

  • Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation.

    Geert Raes;Lea Brys;Bhola K. Dahal;Jef Brandt

  • Comparison of the Biodistribution and Tumor Targeting of Two 99mTc-Labeled Anti-EGFR Nanobodies in Mice, Using Pinhole SPECT/Micro-CT

    Lea Olive Tchouate Gainkam;Lieven Huang;Vicky Caveliers;Marleen Keyaerts

  • The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity.

    Damya Laoui;Jiri Keirsse;Yannick Morias;Eva Van Overmeire

  • Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T-CELL suppressive activity

    Kiavash Movahedi;Martin Guiliams;Jan Van den Bossche;Rafael Van den Bergh

Frequent Co-Authors

Geert Raes
Geert Raes Vrije Universiteit Brussel
Alain Beschin
Alain Beschin Vrije Universiteit Brussel
Stefan Magez
Stefan Magez Ghent University
Jo A. Van Ginderachter
Jo A. Van Ginderachter Vrije Universiteit Brussel
Serge Muyldermans
Serge Muyldermans Vrije Universiteit Brussel
Martin Guilliams
Martin Guilliams Ghent University
Rudolf Lucas
Rudolf Lucas Augusta University
Etienne Pays
Etienne Pays Université Libre de Bruxelles
Frank Brombacher
Frank Brombacher University of Cape Town
Kris Thielemans
Kris Thielemans Vrije Universiteit Brussel

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